Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Study: Medication adherence alone may not benefit employees with chronic conditions

Medication adherence alone may not be enough to impact the productivity of employees with chronic conditions such as depression, diabetes, hypertension and coronary artery disease.

2 Mar 2011

CRT-D therapy benefits heart failure patients with left bundle branch block

Mild heart failure patients with a particular condition that results in disorganized electrical activity throughout the heart benefit substantially from cardiac resynchronization therapy with defibrillator (CRT-D), according to a study published in the American Heart Association journal Circulation.

2 Mar 2011

Geron's hESC derived GRNCM1 halts remodeling process and preserves cardiac function in acute heart damage

Geron Corporation today announced preclinical study data showing positive effects of GRNCM1, Geron's cardiomyocyte product derived from human embryonic stem cells (hESCs), in a small animal model of acute heart damage. Administering GRNCM1 by injection into the heart resulted in greater resistance to induced arrhythmias, halted adverse cardiac remodeling and preserved mechanical function compared to controls.

2 Mar 2011

High blood pressure medications useful even in those without hypertension: Study

Researchers have studied existing evidence to suggest that people who have had a stroke or a heart attack might benefit from taking blood pressure medications, even if they do not have high blood. They noted that for every 1,000 people taking the drugs in clinical trials, on average 15 fewer died from heart disease than when the patients got dummy treatment. The study however could not explain the cause for this benefit. The study, which was funded by Tulane University and the National Institutes of Health, was published in the March 2 issue of the Journal of the American Medical Association.

1 Mar 2011

Routine blood test can reduce hospital readmissions in patients with heart failure

An inexpensive, routine blood test could hold the key to why some patients with congestive heart failure do well after being discharged from the hospital and why others risk relapse, costly readmission or death within a year, new Johns Hopkins research suggests.

1 Mar 2011

Decision Resources: 52% of surveyed cardiologists identify furosemide as efficacious acute heart failure therapy

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the highest proportion of surveyed cardiologists identify furosemide as the most efficacious agent for the treatment of acute heart failure when compared to other available therapies.

1 Mar 2011

Nile plans to develop novel therapeutics for ADHF

Nile Therapeutics, Inc., a biopharmaceutical company focused on the development of novel therapeutics for cardiovascular disease, announced plans to pursue a new indication in the field of heart failure.

1 Mar 2011

CellSeed, LA BioMed enter two-year research agreement to study core technology in regenerative medicine

Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and CellSeed Inc., a Japanese biotechnology firm, have entered into a two-year research agreement to study CellSeed's proprietary core technology in regenerative medicine, "Cell Sheet Engineering," LA BioMed President and CEO David I. Meyer, PhD, announced today.

28 Feb 2011

Free radicals make the heart to beat with the correct force

Fear of free radicals may be exaggerated, according to scientists from the Swedish medical university Karolinska Institutet. A new study, published in the Journal of Physiology, shows that free radicals act as signal substances that cause the heart to beat with the correct force.

28 Feb 2011

New study: Free radicals play a key role in heart physiology

Fear of free radicals may be exaggerated, according to scientists from the Swedish medical university Karolinska Institutet. A new study, published in The Journal of Physiology, shows that free radicals act as signal substances that cause the heart to beat with the correct force.

28 Feb 2011

Dizziness, nausea and achiness are symptoms of heart attack in females

Dizziness, nausea and achiness – no, these are not symptoms of the flu but signs of a heart attack in females. While heart attacks affect both men and women, the symptoms of a heart attack are surprisingly different between the genders. Virginia Health Information (VHI) this week released its Cardiac Care Report which provides consumers information comparing heart healthcare in Virginia. This year's report reveals women undergoing open heart surgery continued a five year trend of higher than expected readmission rates.

25 Feb 2011

Genentech granted FDA hearing on Avastin for metastatic breast cancer

Genentech, a member of the Roche Group, today announced the U.S. Food and Drug Administration (FDA) has granted a hearing to allow the company the opportunity to present its views on why Avastin® (bevacizumab) should remain FDA-approved for metastatic breast cancer (mBC). The FDA has scheduled the hearing for June 28 to 29, 2011.

25 Feb 2011

PHA partners with NORD, EURORDIS to raise global awareness about PH

Pulmonary hypertension is a rare, under-diagnosed disease that can strike people at any time, affecting newborns to the elderly or anyone in between. To raise global awareness of this invisible disease, the Pulmonary Hypertension Association is partnering with the National Organization for Rare Disorders and Rare Diseases Europe on Feb. 28, 2011, to observe Rare Disease Day.

25 Feb 2011

FN-EDA protein can reduce damage after heart attack

Scientists have identified a protein that plays a key role in debilitating changes that occur in the heart after a heart attack, according to research reported in Circulation Research: Journal of the American Heart Association.

25 Feb 2011

Study finds link between fasting serum glucose levels and in-hospital mortality in elderly non-diabetic patients

A two-country hospital study of 808 elderly patients found a strong association between high, undiagnosed blood glucose in non-diabetic patients and increased hospital death rates, according to the March issue of IJCP, the International Journal of Clinical Practice.

24 Feb 2011

Trevena commences TRV120027 Phase 2a trial in patients with acute heart failure

Trevena Inc., the leader in G-protein coupled receptor biased ligand drug discovery, today announced the initiation of a Phase 2a clinical trial with its lead program, TRV120027, a beta-arrestin biased angiotensin II type 1 receptor ligand, the first biased ligand designed to treat patients with acute heart failure.

23 Feb 2011

Dual lab tests accurately predict vein graft blood clots in patients during CABG

A team of heart experts at Johns Hopkins has found that dual lab tests of blood clotting factors accurately predict the patients whose blood vessels, in particular veins implanted to restore blood flow to the heart during coronary artery bypass grafting, are more likely to fail or become clogged within six months.

23 Feb 2011

HealthGrades recognizes America's 50 Best Hospitals for 2011

HealthGrades America's 50 Best Hospitals for 2011 were identified in a report issued today by the leading independent healthcare ratings organization. These hospitals demonstrated superior and sustained clinical quality over an eleven year time period, based on an analysis of more than 140 million Medicare patient records.

23 Feb 2011

Researchers find endothelial dysfunction can predict risk of coronary heart disease

A new study from the Libin Cardiovascular Institute at the University of Calgary's Faculty of Medicine is shedding light on an underlying cause of heart disease.

22 Feb 2011

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Congenital heart diseases affect approximately one in 100 patients, making them the most common type of birth defect and the number-one cause of pediatric deaths.

21 Feb 2011

Heart Failure News and Research

Further Reading

Study: Medication adherence alone may not benefit employees with chronic conditions

CRT-D therapy benefits heart failure patients with left bundle branch block

Geron's hESC derived GRNCM1 halts remodeling process and preserves cardiac function in acute heart damage

High blood pressure medications useful even in those without hypertension: Study

Routine blood test can reduce hospital readmissions in patients with heart failure

Decision Resources: 52% of surveyed cardiologists identify furosemide as efficacious acute heart failure therapy

Nile plans to develop novel therapeutics for ADHF

CellSeed, LA BioMed enter two-year research agreement to study core technology in regenerative medicine

Free radicals make the heart to beat with the correct force

New study: Free radicals play a key role in heart physiology

Dizziness, nausea and achiness are symptoms of heart attack in females

Genentech granted FDA hearing on Avastin for metastatic breast cancer

PHA partners with NORD, EURORDIS to raise global awareness about PH

FN-EDA protein can reduce damage after heart attack

Study finds link between fasting serum glucose levels and in-hospital mortality in elderly non-diabetic patients

Trevena commences TRV120027 Phase 2a trial in patients with acute heart failure

Dual lab tests accurately predict vein graft blood clots in patients during CABG

HealthGrades recognizes America's 50 Best Hospitals for 2011

Researchers find endothelial dysfunction can predict risk of coronary heart disease

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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