Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

End-of-life care documentation helps in emergency treatment decisions

When Heather Rubesch was a teenager, her aunt died in need of a kidney transplant. In later family discussions, Heather's mother, Linda, expressed some of her views about end-of-life care—for instance, her belief in organ donation.

19 Apr 2010

Heart transplant patient skis to the North Pole

They made it! In what is believed to be a world-first, a heart transplant patient along with his transplant doctor skied over 100 miles, over ice, snow drifts, across open water, through gale-force winds and freezing temperatures to make it to the North Pole early Thursday morning.

17 Apr 2010

Research roundup: Revamping NCI Clinical Trials, reducing malpractice suits, health disparities persist

A National Cancer Clinical Trials System For The 21st Century: Reinvigorating The NCI Cooperative Group Program - The "system for conducting cancer clinical trials in the United States is approaching a state of crisis," according to this report on inefficiencies and funding issues faced by the NCI's Clinical Trials Cooperative Group Program - which comprises 10 groups, more than 3,100 institutions, 14,000 investigators and more than 25,000 patients in clinical trials each year.

17 Apr 2010

Researchers study effectiveness of TeleCare in keeping individuals healthy

Like the bleeps of an alarm clock, TeleCare, a home monitoring device, gives the chronically ill a wake-up call: "It's time to take your vitals."

17 Apr 2010

Results of study comparing REMICADE to azathioprine for Crohn's disease published

Findings published today in The New England Journal of Medicine from a first-of-its-kind comparator trial evaluating the anti-tumor necrosis factor (TNF)-alpha biologic treatment REMICADE (infliximab) in the treatment of moderately to severely active Crohn's disease in patients who were naive to immunomodulator and biologic therapy, showed that a significantly greater proportion of patients receiving REMICADE achieved steroid-free remission and mucosal healing compared with patients receiving azathioprine.

16 Apr 2010

Embryos with two mums to remove the risk of hereditary diseases: new research

New research published in the journal Nature, could pave the way to world’s first genetically modified human baby. The research involves making embryos with genes from one man and two women. There are hundreds or families around the world who are left childless or have serious ill babies because they carry genes for hereditary illnesses. This research may bring hope to such couples. According to scientists on the team, within the next three years these women will be able to avail such techniques. There has been skepticism regarding ethical issues attached to making of “designer babies”.

16 Apr 2010

Watson Laboratories' ANDA for generic Toprol XL tablets receives FDA approval

Watson Pharmaceuticals, Inc., today announced that its subsidiary, Watson Laboratories, Inc. - Florida, has received approval from the United States Food and Drug Administration on its Abbreviated New Drug Application for metoprolol succinate extended-release tablets USP in the 100 and 200 mg strengths, the generic equivalent to AstraZeneca's Toprol XL® tablets.

16 Apr 2010

Regulus Therapeutics' metabolic disease program data presented at Diabetes Keystone Symposium

Regulus Therapeutics Inc. today announced that new data from its metabolic disease program were presented at the "Diabetes" Keystone Symposium held April 12-17 in Whistler, British Columbia. The new pre-clinical research findings showed that therapeutic oligonucleotides targeting microRNA are able to improve insulin resistance and normalize plasma glucose in mouse models of diabetes while having no significant effect on glucose or insulin levels in normal mice.

16 Apr 2010

Ibuprofen demonstrates efficacy over acetaminophen for treatment of pain and fever

Cumberland Pharmaceuticals Inc. today announced results from a meta-analysis comparing the efficacy and safety of ibuprofen and acetaminophen, which was published in the March edition of the peer-reviewed journal The Annals of Pharmacotherapy. The publication notes that in a majority of evaluated studies ibuprofen demonstrated superior efficacy compared to acetaminophen for the treatment of pain and fever, and found no significant safety differences between the drugs.

15 Apr 2010

Successful stem cell therapy performed on CHF patients in Mexico

Bioheart, Inc. announced that treatment with stem cell therapy on two congestive heart failure (CHF) patients was performed successfully at the Hospital Angeles Tijuana, Mexico, through Bioheart's Center of Excellence program with Regenerative Medicine Institute.

15 Apr 2010

$SBUMC adds Toshiba Aquilion ONE \320-detector row CT system with pediatric imaging capabilities$

SBUMC adds Toshiba Aquilion ONE \320-detector row CT system with pediatric imaging capabilities

A new state-of-the art computed tomography (CT) scanner that provides physicians with precise images of internal organs with a single rotation of the gantry is now in operation at Stony Brook University Medical Center (SBUMC), adding to the hospital's advanced scanner technology.

15 Apr 2010

Beckman Coulter awarded new agreement with Premier Purchasing Partners for laboratory systems and supplies

Beckman Coulter, Inc., a leading developer, manufacturer, and marketer of products that simplify, automate, and innovate complex biomedical testing, announced that effective April 1, 2010, it has been awarded a new agreement with Premier Purchasing Partners, the group purchasing unit of Premier, Inc., to provide a full range of core laboratory systems and supplies. Premier is one of the nation's largest healthcare purchasing networks, with more than 2,300 member hospitals and 64,000 additional healthcare sites.

From Beckman Coulter Diagnostics 15 Apr 2010

New research indicates exercise-based rehabilitation can benefit heart failure patients

Your heart is an incredible muscle, pumping an estimated 2,000 gallons of blood through about 60,000 million miles of blood vessels — and beating maybe 100,000 times a day, year after year after year.

15 Apr 2010

Family support critical for managing patients with chronic health problems

Almost 40 percent of chronically ill older adults in the U.S. live alone, and a majority of those who are married have spouses with at least one chronic illness that can affect their ability to provide support, according to a U-M study published in the journal Chronic Illness.

15 Apr 2010

Trevena commences Phase I trial of TRV120027 biased ligand for acute decompensated heart failure

Trevena Inc., a leader in the discovery of G-protein coupled receptor (GPCR) biased ligands, today announced the initiation of a Phase I clinical trial of TRV120027, a titratable i.v. agent designed for the treatment of acute decompensated heart failure. TRV120027 is a biased ligand that targets the angiotensin II type 1 receptor (AT1R) and induces a unique mode of signaling.

15 Apr 2010

XOMA expands anti-inflammatory antibody intellectual property portfolio

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced that the U.S. Patent and Trademark Office has issued two new patents that significantly expand the company's intellectual property portfolio relating to its anti-inflammatory antibody, XOMA 052, that targets interleukin-1 beta (IL-1 beta).

13 Apr 2010

Older patients more likely to die in hospital following implantation of defibrillators: Report

Older patients may be more likely to die in the hospital following the implantation of defibrillators or pacemakers, according to a report in the April 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

13 Apr 2010

Researchers evaluate new treatment for coronary heart disease

Some patients with heart muscles seriously affected by coronary heart disease may soon be able to benefit from an innovative treatment.

13 Apr 2010

Transgenic mouse model study confirms passage of maternal thyroid hormones to fetus

Until now there were only indirect evidence of the transfer of thyroid hormones from mother to fetus through the placenta during pregnancy. That event is very important because the maternal thyroid hormones appear to play a key role in the development of the nervous system and other organs of the fetus; so it's true that in case of maternal thyroid disease, such hypothyroidism, have a direct bearing on the unborn child with reduction, also significant, to its Q.I..

12 Apr 2010

Idaho man fourth in country to receive Levacor- VAD implant

After receiving only the fourth U.S. implant of a new-generation, Utah-made ventricular assist (VAD ) device, an Idaho man with heart failure is looking forward to resuming an active life following an operation on March 17 at University of Utah Hospital.

9 Apr 2010

Heart Failure News and Research

Further Reading

End-of-life care documentation helps in emergency treatment decisions

Heart transplant patient skis to the North Pole

Research roundup: Revamping NCI Clinical Trials, reducing malpractice suits, health disparities persist

Researchers study effectiveness of TeleCare in keeping individuals healthy

Results of study comparing REMICADE to azathioprine for Crohn's disease published

Embryos with two mums to remove the risk of hereditary diseases: new research

Watson Laboratories' ANDA for generic Toprol XL tablets receives FDA approval

Regulus Therapeutics' metabolic disease program data presented at Diabetes Keystone Symposium

Ibuprofen demonstrates efficacy over acetaminophen for treatment of pain and fever

Successful stem cell therapy performed on CHF patients in Mexico

SBUMC adds Toshiba Aquilion ONE \320-detector row CT system with pediatric imaging capabilities

Beckman Coulter awarded new agreement with Premier Purchasing Partners for laboratory systems and supplies

New research indicates exercise-based rehabilitation can benefit heart failure patients

Family support critical for managing patients with chronic health problems

Trevena commences Phase I trial of TRV120027 biased ligand for acute decompensated heart failure

XOMA expands anti-inflammatory antibody intellectual property portfolio

Older patients more likely to die in hospital following implantation of defibrillators: Report

Researchers evaluate new treatment for coronary heart disease

Transgenic mouse model study confirms passage of maternal thyroid hormones to fetus

Idaho man fourth in country to receive Levacor- VAD implant

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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