Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Herceptin does not increase heart failure in patients long-term

Risk of congestive heart failure in women treated with trastuzumab (Herceptin) and combination chemotherapy for early-stage breast cancer did not increase over time according to a five-year follow-up of National Surgical Adjuvant Breast and Bowel Project (NSABP) trial B-31, presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

5 Jun 2007

Benefits of Herceptin are lasting

An updated analysis of two large randomized clinical trials has found that breast cancer patients who received the monoclonal antibody trastuzumab (Herceptin) along with chemotherapy are living longer and with less risk of recurrent disease, compared to patients treated with chemotherapy alone.

5 Jun 2007

Simple exercise test predicts mortality risk in heart failure patients

A simple exercise test may help predict mortality risk in patients with heart failure and help doctors to better tailor treatment strategies, according to new research from Wake Forest University Baptist Medical Center.

1 Jun 2007

More considered approach to the safety of rosiglitazone needed

A calmer and more considered approach to the safety of rosiglitazone (Avandia) - the GlaxoSmithKline treatment for type 2 diabetes - is needed to avoid unnecessary panic among patients, says an Editorial published online and in an upcoming edition of The Lancet.

28 May 2007

Heart-assist device gives Culver City man a better quality of life

Mark Heiner of Culver City reads books, paints artistically, takes walks and does laundry – activities that would be considered routine except for the fact that a four-pound disk implanted in his abdominal cavity is keeping his blood flowing.

28 May 2007

Gene therapy used to reverse heart failure in animals

Heart researchers at the Center for Translational Medicine at Jefferson Medical College have used gene therapy to reverse heart failure in animals.

24 May 2007

Study of VentrAssist heart support device as a bridge to transplantation

Doctors at UPMC have begun a study using an investigational cardiac device, the VentrAssist, Left Ventricular Assist System (LVAD) to see whether it can be used safely and effectively in patients with end-stage heart failure.

23 May 2007

Combination of medicines best for blood pressure control

Millions of Americans take medications for hypertension but do not achieve control of their blood pressure.

22 May 2007

FDA in trouble over widely used diabetic drug Avandia

A diabetes pill which has been widely used since 1999 is now suspected of increasing the risk of heart attacks for those taking it.

22 May 2007

First beating heart transplant procedure in the US

Protected by its own nutrients and blood supply, a beating heart supported by an investigational organ preservation device was successfully transplanted into a 47-year-old man with congestive heart failure and pulmonary hypertension on Sunday, April 8.

18 May 2007

Quality improvement effort pays off in diabetes care

Spending money to improve diabetes care at federally qualified community health centers is a sound investment, according to one of the first studies to examine the clinical and economic impact of quality improvement on diabetes care.

18 May 2007

Pycnogenol natural pine bark extract reduces heart failure

A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart.

17 May 2007

Low tar cigarettes as damaging as regular tar

Low tar "lite" cigarettes impair blood flow through the heart as severely as regular cigarettes, reveals a small study published ahead of print in the journal Heart.

16 May 2007

Gender disparities in heart disease and diabetes managed care

Women with heart disease and diabetes are less likely to receive several types of routine outpatient medical care than men who have similar health problems, according to a RAND Corporation study issued today.

16 May 2007

Online heart disease education program helps patients

Patients who used the American Heart Association's online heart disease education program were more aware of treatment options than other patients, researchers reported at the American Heart Association's 8th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke.

16 May 2007

Single-tablet combination of atorvastatin and amlodipine for high blood pressure effective

Adults with high blood pressure and additional risk factors for heart disease may benefit more from taking one tablet rather than two, if their current treatment combines the lipid-lowering medication atorvastatin with the blood pressure-lowering medication amlodipine, researchers reported at the American Heart Association's 8th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke.

16 May 2007

Heart-failure patients take their medicine more reliably when under the care of a pharmacist

...resulting in fewer emergency-room visits and hospital stays as well as lower health-care costs, according to a study from the University of North Carolina at Chapel Hill School of Pharmacy.

15 May 2007

Mending broken hearts

The causes of "broken heart syndrome" remain a mystery, but doctors will soon have an easier time recognizing and treating this rare, life-threatening condition, thanks to data being reported at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI), May 9-12, 2007, in Orlando, FL.

11 May 2007

Catheter-based aortic valve replacement is set to take off

Twenty years ago, few interventional cardiologists could have imagined that during their professional careers it would be possible to replace a diseased aortic valve using catheter-based techniques, rather than open-chest surgery.

11 May 2007

Percutaneous aortic valve replacement safe

Catheter techniques are expanding into new territory, successfully aiding in the replacement of narrowed, calcified aortic valves in patients too sick to withstand open-chest surgery.

11 May 2007