Heart Transplantation News and Research

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A heart transplant is an operation in which the diseased heart in a person is replaced with a healthy heart from a deceased donor. Ninety percent of heart transplants are performed on patients with end-stage heart failure.

Heart failure is a condition in which the heart is damaged or weakened and can't pump enough blood to meet the body's needs. "End-stage" means the condition has become so severe that all treatments, other than heart transplant, have failed.

Study finds benefits, less organ rejection using immunosuppressive combination for heart transplants

A new study led by researchers at the UCLA Heart Transplant Program showed that one particular combination using tacrolimus (TAC or PrografÒ also known as FK506) had significant anti-rejection benefits for heart transplant patients over other combinations.

22 May 2005

Mutated gene causes serious heart disease in newborns

The research group of professor Manfred Kilimann at the Department of Cell and Molecular Biology has elucidated the genetic cause of a severe heart disease in newborn children. This result will be published in the June issue of the American Journal of Human Genetics this week.

3 May 2005

FDA expert panel to review Abiomed's artificial heart

Abiomed, Inc. today announced that the U.S. Food and Drug Administration (FDA) will convene an expert panel of cardiovascular surgeons and cardiologists to review the groundbreaking technologies and clinical trial data behind the AbioCor artificial heart.

20 Apr 2005

Heart transplant patients benefit from new technology

New technology for cardiac transplant patients indicates a patient's risk of organ rejection with a simple blood test. News of this revolutionary testing method will be presented today at the International Society for Heart and Lung Transplantation's (ISHLT) Annual Meeting and Scientific Session in Philadelphia.

6 Apr 2005

Infants under one year of age can accept heart transplants from donors of different blood groups

A study showing that infants under one year of age can accept heart transplants from donors of different blood groups without the risk of organ rejection means a better chance of survival for infant patients and more efficient use of donor organs overall.

4 Apr 2005

Small hearts make big difference for young transplant recipients

When a young child is in need of a heart transplant, the problem is not the intricate surgery, but the scarcity of donors.

1 Mar 2005

Older heart transplant recipients fare just as well as their younger counterparts

Policy makers who use age as a discriminating factor in determining eligibility for heart transplant surgery may want to reconsider their rules in the light of new research at the University of Alberta.

14 Feb 2005

Basic biochemical composition of heart valves in patients with congestive heart failure are markedly different than those with healthy hearts

Surprising new findings in the Journal of the American College of Cardiology show that the basic biochemical composition of heart valves in patients with congestive heart failure are markedly different than those with healthy hearts, a finding that may explain the mixed success of surgery to repair valve dysfunction in these patients.

25 Jan 2005

Two hearts are better than one for toddler

Camila Gonzalez now has two hearts beating separate rhythms inside her tiny chest. At 22 months of age, she became the youngest child in the United States to receive a donor’s heart while also retaining her original one.

25 Oct 2004

Study suggests intramyocardial injection of cells from bone marrow might be an alternative for heart transplantation

Cardiovascular disease remains the leading cause of morbidity and mortality around the world and patients with end-stage ischemic heart failure carry the highest morbid-mortality rate.

30 Aug 2004

Artificial heart can keep patients awaiting heart transplant alive

The results of the nine-year study of the CardioWest Total Artificial Heart have concluded that the device prevents death in critically ill patients suffering from irreversible failure of both sides of the heart who are candidates for heart transplantation.

26 Aug 2004

ABIOMED has announced the 14th implantation of replacement heart

ABIOMED, Inc. today announced the 14th implantation of the AbioCor® Implantable Replacement Heart. The implant was performed on May 24 in Louisville, KY by a Jewish Hospital/University of Louisville medical team led by surgeons Laman Gray, M.D. and Rob Dowling, M.D. The procedure went well and without complication. The patient is recovering, and is in critical but stable condition.

27 May 2004

Arrow LionHeart heart-assist device patient receives heart transplant

Gayle Snider, the first U.S. patient to go home from the hospital with an Arrow LionHeart heart-assist device, received a heart transplant Saturday, May 22, at Penn State Milton S. Hershey Medical Center.

23 May 2004

Embryonic stem cells may hold the key to regenerating damaged heart muscle

Embryonic stem cells may hold the key to regenerating damaged heart muscle, when transplanted within a 3-dimensional scaffold into the infracted heart, according to a new study coming out in June in the Journal of Heart and Lung Transplantation.

14 May 2004

Thoratec gets FDA approval for increased enrollment and Medicare expansion for heart pump

Thoratec Corporation, a manufacturer of products to treat cardiovascular disease, has announced the expansion of its Phase I feasibility trial for the HeartMate(R) II left ventricular assist system (LVAS).

12 May 2004

Heart pumps better than medical therapy in keeping heart failure patients alive

Left ventricular assist devices (LVADs) – heart pumps – worked better than medical therapy in keeping seriously ill congestive heart failure patients alive, despite an increased risk of neurological complications, researchers report in today’s rapid access issue of Circulation: Journal of the American Heart Association.

6 May 2004

$4.5 million contract to develop heart assist devices for infants

The University of Pittsburgh's McGowan Institute for Regenerative Medicine has been awarded a five-year $4.5 million contract from the National Heart, Lung, and Blood Institute to develop a heart assist device for infants.

28 Apr 2004

CellCept linked to reduced cancer incidence

A study presented today at an international transplant meeting showed that heart transplant patients treated with the immunosuppressant CellCeptÒ (mycophenolate mofetil) in standard immunosuppressive regimens had a significantly lower risk of developing cancer compared to those receiving non-CellCept-based treatment regimens.

23 Apr 2004

Sleep apnea may be commonly misdiagnosed with hypertension

Patients with sleep apnea may be commonly misdiagnosed with hypertension, says a study published in the March issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians. In the study, one-third of patients with sleep apnea who were physician-diagnosed with hypertension actually had "white coat hypertension" (WCH), a condition characterized by an increase in blood pressure during a doctor's office visit and normal blood press during all other situations.

20 Mar 2004