High Cholesterol News and Research

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Treatment with atorvastatin cut incidence of stroke by almost a half

Patients with Type 2 diabetes and a CV risk factor would benefit from a cholesterol-lowering medicine according to results from the first ever specifically designed UK primary prevention statin trial announced today at the American Diabetes Association (ADA)2.

7 Jun 2004

Combination treatment may help type 2 diabetes patients

New research presented by Peter Weissman, M.D., from the University of Miami, at the 64th Annual Scientific Sessions of the American Diabetes Association shows that combination treatment with rosiglitazone maleate and metformin significantly improves certain markers of cardiovascular disease risk in patients with type 2 diabetes compared to metformin alone.

6 Jun 2004

New advice to doctors on lowering diabetes-heart disease risks

Every year, the American Diabetes Association (ADA) issues Clinical Practice Recommendations, a series of updated recommendations, to help health care providers treat people with diabetes using the most current research available.

5 Jun 2004

BMA to publish an A to Z of Doctors Making a Difference

The British Medical Association will today (Thursday 3 June 2004) publish an A to Z of Doctors Making a Difference. This UK-wide report illustrates how doctors are leading developments to increase patient care, improve access to services and enhance the patient experience.

3 Jun 2004

Pollution can contribute to the development of cardiovascular diseases

Journal of the American Heart Association reports that exposure to air pollution can contribute to the development of cardiovascular diseases.

2 Jun 2004

Atkins high-fat-low-carbohydrate diet may have caused severe heart disease

A Florida businessman filed suit today against Atkins Nutritionals, Inc., and the Estate of Dr. Robert C. Atkins, claiming that the late diet author’s controversial high-fat, low-carbohydrate regimen caused severe heart disease, necessitating angioplasty and a stent. He is seeking a court injunction banning Atkins Nutritionals from marketing its products without a warning of potential health risks and asks for compensatory damages.

31 May 2004

Antioxidant compound found in green tea leaves does not clear established plaque

Using a technique that enables them to study both early and advanced stages of arterial plaque buildup in the same mice, researchers at Cedars-Sinai Medical Center found that an antioxidant compound found in green tea leaves does not clear established plaque but does inhibit the development of new deposits.

24 May 2004

Moderate exercise in conjunction with common dietary supplements significantly reduce the risk of atherosclerosis

Moderate exercise in conjunction with common dietary supplements significantly reduce the risk of atherosclerosis because, combined, they boost the body’s production of nitric oxide, which protects against a variety of cardio-vascular disorders, a new UCLA study led by 1998 Nobel Laureate in medicine Louis J. Ignarro shows.

24 May 2004

Study has important implications for African Americans who suffer from high blood pressure

A new study has important implications for the millions of African Americans who suffer from high blood pressure. The study, AADVANCE, shows Diovan HCT(R) (valsartan and hydrochlorothiazide) lowers blood pressure in African Americans to aggressive recommended target blood pressure goals as effectively as amlodipine.

20 May 2004

Dark chocolate and cocoa may help arterial stiffness

“This is the first study to investigate whether chocolate has any favorable effects on cardiovascular function in healthy subjects,” says Charalambos Vlachopoulos, MD, of the Athens Medical School, Athens, Greece. “We found dark chocolate improves endothelial function and decreases arterial stiffness in healthy young adults.”

19 May 2004

Faster growing babies are at greater risk of heart disease and stroke

Medical Research Council (MRC) and Institute of Child Health scientists say that babies who grow fast are at greater risk of heart disease and stroke in later life. Because breast-fed babies grow less rapidly than those fed formula milk, the work strongly reinforces the message that breast feeding is best.

14 May 2004

National effort to detect life-threatening non-cardiac vascular diseases

The University of Arizona Medical Center for the first time will be part of a national effort to detect life-threatening non-cardiac vascular diseases. UMC is partnering with the American Vascular Association to offer free screenings for people at high risk: 60 years or older with a history of hypertension, diabetes, smoking, high cholesterol, or known cardiovascular disease.

14 May 2004

Cardiovascular disease in parents is a major predictor of offspring having a heart attack or stroke

A study published in the May 12 issue of The Journal of the American Medical Association provides the strongest evidence yet that cardiovascular disease in parents -- particularly at an early age -- is a major predictor of their children having a heart attack or stroke in middle age.

12 May 2004

Compound found in the peels of citrus fruit can potentially lower cholesterol more effectively than prescription drugs

A compound found in the peels of citrus fruit has the potential to lower cholesterol more effectively than some prescription drugs, and without side effects, according to a study by U.S. and Canadian researchers.

11 May 2004

How flexing of blood vessels during a heartbeat might contribute to heart disease

Duke biomedical engineers have received more than $2.2 million from the National Institutes of Health (NIH) to continue their explorations of how the complex moving and flexing of blood vessels during a heartbeat might contribute to heart disease.

28 Apr 2004

Test results from 1970s linked to rates of erectile problems 25 years later

Age, obesity, high cholesterol, and high triglyceride measurements in midlife predict not only heart disease risks, but also the likelihood of erectile dysfunction decades later, according to a new study in the April 21, 2004 issue of the Journal of the American College of Cardiology.

20 Apr 2004

Liptor helps Alzheimer’s disease

In a small clinical trial enrolling 63 individuals with Alzheimer’s disease, half of those who received atorvastatin (Lipitor) stabilized or improved after one year of treatment, the trial’s principal investigator D. Larry Sparks, Ph.D., reported today at a professional meeting on Alzheimer therapy.

15 Apr 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

If you want to increase your chances of living longer, taking cholesterol drugs is an easy way to do it. That's the message from a Harvard study of 4,162 people hospitalized in 350 places in eight countries. It is the first research to show that intense lowering of cholesterol results in a major reduction in deaths and severe heart attacks.

7 Apr 2004

First Approval in Europe of Ezetimibe/Simvastatin for treatment of elevated cholesterol

Merck/Schering-Plough Pharmaceuticals today announced the regulatory approval of INEGYTM (ezetimibe/simvastatin) in Germany for the treatment of elevated cholesterol (hypercholesterolemia). INEGY is the first product to reduce low-density lipoprotein cholesterol (LDL-C or ‘bad’ cholesterol), along with diet and exercise, through dual inhibition by inhibiting cholesterol production in the liver and absorption in the intestine. The approval of INEGY in Germany represents the first approval in Europe for ezetimibe/simvastatin tablets and the first step in seeking marketing approval throughout the European Union (EU) under the EU’s mutual recognition procedure.

4 Apr 2004

Walnuts prevent heart disease

A new clinical study shows that substituting walnuts for monounsaturated fat in a Mediterranean diet improves, and even restores, endothelial function (the property of arteries to dilate in order to meet an increased demand of blood, for instance due to a physical effort). Walnuts also reduce harmful cell adhesion molecules which are associated with atherosclerosis, commonly known as hardening of the arteries. These dual effects enhance the circulatory system, therefore aiding in the prevention of heart disease.

23 Mar 2004