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RNAi-based inhibitors for created for nearly every human and mouse gene - available to all genetic researchers

An international public-private research team led by scientists at the Broad Institute of MIT and Harvard announced today the construction and availability of an extensive library of molecular reagents to silence most human and mouse genes.

28 Mar 2006

New technology - desorption electrospray ionization detects the boundaries of cancerous tumors

Researchers at Purdue University have shown how a new ultra-fast chemical-analysis tool has numerous promising uses for detecting everything from cancer in the liver to explosives residues on luggage and "biomarkers" in urine that provide an early warning for diseases.

21 Mar 2006

NHGRI announces comprehensive strategy to identify structural variation in human genome

The National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), has announced its latest round of sequencing targets, with an emphasis on enhancing the understanding of how human genes function and how genomic differences between individuals influence the risk of health and disease.

19 Mar 2006

Discovery in yeast opens door to new source of information on DNA damage, repair, and cancer

The discovery in yeast cells of a genetic network that guards against lethal DNA damage is a first step in the creation of a database of disease-causing combinations of mutated human genes, according to researchers at The Johns Hopkins University School of Medicine led by Jef. D. Boeke, Ph.D.

15 Mar 2006

Menthol discovery could point towards new pain therapies

This new understanding could lead to potential advances in pain therapy, the researchers said. Moreover, the scientists envision that their method may be potentially useful in studying the activation mechanism of other drugs and proteins.

13 Mar 2006

New test for detecting small amounts of proteins in the blood

Researchers at the University of Pennsylvania School of Medicine have developed a paradigm-shifting method for detecting small amounts of proteins in the blood.

13 Mar 2006

Genome signature tagging used to quickly identify and distinguish between pathogens and harmless microbes

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have developed a new, high-throughput technique for identifying the many species of microorganisms living in an unknown "microbial community."

6 Mar 2006

Cell growth and cell division genes identified

A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study.

23 Feb 2006

GeneDesign speeds design of artificial pieces of DNA

Johns Hopkins researchers have announced the development of a Web-based, automated computer program that they say greatly simplifies the time-consuming and error-prone process of manually designing artificial pieces of DNA.

17 Feb 2006

Genome data may contain small but significant errors

Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been elucidated

17 Feb 2006

New DNA-based cell adhesion strategy

A new technique in which single strands of synthetic DNA are used to firmly fasten biological cells to non-biological surfaces has been developed by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley.

9 Feb 2006

Molecular Devices introduces a high-speed, laser-scanning, confocal imager

This system is the latest addition to its Total Imaging Solution which includes the ImageXpressMICRO imaging system, MetaXpress Software Application Modules, AcuityXpress Data Analysis software and the Transfluor Assay for GPCRs.

7 Feb 2006

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

New treatment for the pediatric eye cancer retinoblastoma

Investigators at St. Jude Children's Research Hospital have demonstrated in laboratory studies a new treatment for the pediatric eye cancer retinoblastoma that appears to be more effective than the current standard therapy, and more likely to prevent the recurrence of this cancer. A report on their work appears in the October 15 issue of Clinical Cancer Research.

17 Oct 2005

Researchers find new type of antibiotic against the cholera bacteria

Just as hurricanes in the Gulf states and Guatemala have raised the risks of cholera outbreaks, researchers at Harvard Medical School have identified a new type of antibiotic against the cholera bacteria.

16 Oct 2005

Influenza evolution in action

On the eve of the 2005-06 flu season, scientists at The Institute for Genomic Research (TIGR) have captured influenza evolution in action. In a study published in this week's journal Nature, the researchers report the first large-scale project to sequence the influenza virus.

5 Oct 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Microchip system aims to reduce the number of animals used in the development of new drugs

Reducing the number of animals used in the development of new drugs is a priority for the pharmaceutical industry

26 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.