Hormone Replacement Therapy News and Research

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Hormone Replacement Therapy (HRT) sometimes called estrogent replacement therapy or ERT, refers to a woman taking supplements of hormones such as estrogen alone or estrogen with another hormone called progesterone (progestin in its synthetic form). HRT replaces hormones that a woman’s body should be making or used to make.

Protein effects of hormone replacement therapy uncovered

An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial's clinical results.

30 Apr 2009

Women warned about risks of alternative menopause treatments

Scientists at the University of Adelaide in South Australia are warning women about the use of 'alternative' menopause treatments because many have not been properly tested.

26 Apr 2009

Discrepancies between reports of HRT dangers and supporting data

In recent years, a series of highly publicized reports have warned of increases in breast cancer and other health problems in postmenopausal women who take hormone replacement therapy (HRT).

23 Apr 2009

Scientists use eye tracking to detect mild dementia in humans

Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans.

15 Apr 2009

Soybean chemicals may reduce menopause symptoms

Soy aglycons of isoflavone (SAI), a group of soybean constituent chemicals, have been shown to promote health in a rat model of the menopause.

9 Apr 2009

Radius starts Ppase 2a trial of RAD1901 in menopausal hot flashes

Radius Health ("Radius") announced today that the first patient has been dosed in the company's proof-of-concept Phase 2a study of RAD1901, an investigational selective estrogen receptor modulator (SERM) undergoing clinical evaluation for treatment of vasomotor symptoms (menopausal hot flashes).

24 Mar 2009

Study identifies potential 'safe period' for hormone replacement use

A new study makes important new findings on the role of hormone use on the risk of breast cancer, confirming that the use of estrogen plus progesterone increases the risk of both ductal and lobular breast cancer far more than estrogen-only; suggesting a two-year 'safe' period for the use of estrogen and progesterone; and finding that the increased risk for ductal cancers observed in long-term past users of hormone replacement therapy drops off substantially two years after hormone use is stopped.

2 Feb 2009

Is rapid transition through menopause linked to earlier onset of heart disease?

An evaluation of 203 women as part of the multifaceted Los Angeles Atherosclerosis Study (LAAS) found that those who transitioned more quickly through menopause were at increased risk for a higher rate of progression of "preclinical atherosclerosis" - narrowing of arteries caused by the thickening of their walls.

29 Jan 2009

Oral contraceptives may be safe, but information gaps remain

Introduced in the 1960s, oral contraceptives have been used by about 80 percent of women in the United States at some point in their lives.

15 Jan 2009

Natural 'defence' gene reveals how oestrogen fuels cancer

CANCER RESEARCH UK scientists have shown for the first time how a natural 'defence' gene involved in fighting infections such as common colds, can be triggered by hormones to ignite and drive cancers like breast, ovarian, and possibly prostate cancer. Their findings are published in the Journal of Experimental Medicine.

13 Jan 2009

New online tool for calculating colorectal cancer risk

A new online tool for calculating colorectal cancer risk in men and women age 50 or older was launched today, based on a new risk-assessment model developed by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

1 Jan 2009

Positron emission mammography effective in detecting breast cancer

A study has found that positron emission mammography (PEM), a new technique for imaging the breast, is not affected by either breast density or a woman's hormonal status, two factors that limit the effectiveness of standard mammography and MRI at detecting cancer.

3 Dec 2008

How to handle the menopause - eat less, get more active and wear HRT skin patches

The latest advice to women going through the menopause is eat less, get more active and consider wearing hormone replacement therapy (HRT) skin patches.

25 Nov 2008

Weight gain during menopause

Weight and appetite experts from around the world met at a conference in Bangkok earlier this year to discuss sex differences in obesity.

24 Nov 2008

Sex hormones may affect atherosclerosis

Naturally produced sex hormones may influence the risk and progression of atherosclerosis, or hardening of the arteries, Johns Hopkins researchers report in a recent study.

11 Nov 2008

Testosterone patches charge up older women's sex

According to research by an international team of scientists testosterone could recharge the sex lives of older women.

10 Nov 2008

Chronic kidney disease and women's sexuality and gynecologic health

Chronic kidney disease (CKD) exacts a significant toll on a woman's sexuality and gynecologic health. The various effects of kidney failure and its treatments on women's sexual health from adolescence through menopause will be the topic of an in-depth series of presentations at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

8 Nov 2008

Danish study provides new information on hormone replacement therapy and the risk of heart attacks

It's not what you take but the way that you take it that can produce different results in women who take hormone replacement therapy (HRT), according to new research on the association between HRT and heart attacks, published online in Europe's leading cardiology journal, the European Heart Journal today.

30 Sep 2008

Women warned about talcum powder ovarian cancer risk

Scientists have issued a warning to women about using talcum powder - they say it increases their risk of developing ovarian cancer.

29 Sep 2008

Concert Pharmaceuticals initiates CTP-347 phase I clinical trial

Concert Pharmaceuticals, Inc. announced today that it has initiated a Phase I study in healthy volunteers to evaluate the safety, tolerability and pharmacokinetics of CTP-347, a novel deuterium-containing serotonin modulator created by Concert researchers.

25 Sep 2008