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Review of adenotonsillectomy surgery in children

Children who gain weight rapidly after having their tonsils and adenoids removed to treat sleep-disordered breathing (SDB) may improve in the short-term, but over time they may relapse or even worsen.

17 Mar 2008

Researchers discover signaling system that halts the growth of a childhood brain cancer

A discovery by St. Jude Children's Research Hospital scientists suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor.

17 Mar 2008

Discovery of new mechanism involved in inflammatory diseases

Investigators at Hospital for Special Surgery have identified a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis.

17 Mar 2008

Advair reduces asthma-related hospitalization and emergency department visits

Advair Diskus (fluticasone propionate and salmeterol inhalation powder) was associated with fewer asthma-related hospitalizations and emergency department (ED) visits in pediatric patients when compared to the use of inhaled corticosteroids (ICS) alone, and use of Advair by pediatric and adult patients through the summer was associated with fewer hospitalizations and ED visits in the fall.

17 Mar 2008

Medical emergency protocols should be upgraded and optimised on all major airlines

Osman Dar, a clinical fellow at Addenbrooke's Hospital in Cambridge shares his experience of treating an elderly man with crushing chest pain on a flight to Africa.

17 Mar 2008

Investigational drug Debio-025 tested for preventing muscle fiber death in muscular dystrophy

An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD).

17 Mar 2008

Depression is not always manifested in children as dejection and anhedonia

Depending on the age of the child, the dominant features may be weeping, irritability or defiance, as explained by Prof. Claudia Mehler-Wex and Dr. Michael Kölch of Ulm University in the new edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2008; 105(9): 149-55).

17 Mar 2008

Call to restrict the marketing of junk food to children

Louise Baur, Professor of the Discipline of Paediatrics & Child Health at the University of Sydney and Consultant Paediatrician at The Children's Hospital at Westmead, says that parents are struggling to be heard over the bombardment of marketing aimed at their children.

17 Mar 2008

Toddlers affected most by secondhand smoke exposure at home

Secondhand smoke in the home appears to induce markers for heart disease as early as the toddler years, researchers reported at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

14 Mar 2008

First clinical trial data of a fully bioabsorbable drug-eluting stent

Data published today in The Lancet from ABSORB, the world's first clinical trial of a fully bioabsorbable drug eluting stent for the treatment of coronary artery disease, demonstrated no stent thrombosis, no clinically driven target lesion revascularizations (re-treatment of a diseased lesion), and a low (3.3 percent) rate of major adverse cardiac events (MACE) in 30 patients out to one year.

14 Mar 2008

Study explains fundamental process of tumor growth

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

14 Mar 2008

Researchers make case for standardized analysis of cardiac imaging

For accuracy's sake, medical professionals should use the same software for comparing and analyzing diagnostic heart images taken from different time periods and laboratories, a team of researchers has concluded.

14 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

14 Mar 2008

New drug protects nerve cells from damage in mice

Multiple sclerosis (MS) is a chronic inflammatory disease of the brain and spinal cord. Individuals with MS develop progressive neurological disability, and this is thought to be caused by degradation of the nerve cells.

14 Mar 2008

MGH initiates trial to reverse type 1 diabetes

Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes.

14 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

14 Mar 2008

Damaged veins heal faster with heparin treatment, laboratory study finds

A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center.

14 Mar 2008