Hydrocephalus News and Research

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Hydrocephalus is an abnormal buildup of cerebrospinal fluid in the ventricles of the brain.

Researchers evaluate use of regenerative human umbilical cord for in-utero spina bifida repair

In a study to be presented Saturday, Jan. 28, in the oral concurrent session at 8:45 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers evaluated a possible regenerative patch by using human umbilical cord in two studies titled Cryopreserved Human Umbilical Cord (HUC) vs Acellular Dermal Matrix (ADM) for In-Utero Spina Bifida Repair and the study Conventional vs cryopreserved human umbilical cord (HUC) patch based on repair for in-utero spina bifida in a sheep model.

23 Jan 2017

Researchers evaluate effects of laser tissue welding on spina bifida repair

In a study to be presented Saturday, Jan. 28, in the oral concurrent session at 8:45 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers at Baylor College of Medicine, Houston, Texas; IBEX, Logan, Utah; and Laser Tissue Welding Inc., Houston, Texas collaborated on a study titled, Evaluation of the effects of laser tissue welding on the spinal cord and skin in a 30 day study of simulated spina bifida repair in rabbits.

23 Jan 2017

Research into common congenital brain defect identifies molecular basis

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have discovered a molecular cause of hydrocephalus, a common, potentially life-threatening birth defect in which the head is enlarged due to excess fluid surrounding the brain.

14 Dec 2016

Investigational biomarker surpasses current gold standard test for identifying brain shunt infections

In a study of children with brain shunts at Children's of Alabama, a University of Alabama at Birmingham investigational biomarker outperformed the current "gold standard" test for detecting bacterial infections in the shunts.

30 Aug 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

Defects in cerebrospinal fluid flow may contribute to scoliosis during adolescence

A new study in zebrafish suggests that irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence.

13 Jun 2016

Way forwards CLEARing for IVH intervention

Results of the CLEAR III trial point the way forwards for the treatment of patients with intraventricular haemorrhage.

18 Feb 2016

Vascular risk factors implicated in normal pressure hydrocephalus

Researchers have found that vascular risk factors are associated with idiopathic normal pressure hydrocephalus and could be a possible target for intervention.

22 Jan 2016

Loyola neurosurgeon examines issue of hydrocephalus in Uganda

Every year, thousands of babies worldwide die from untreated hydrocephalus, a condition in which the head swells from a buildup of excess fluid. But no baby need die from this condition, once called "water on the brain." Neurosurgeons now have the skills and tools to deal with the condition very effectively.

13 Jan 2016

YAP protein appears to play vital role in helping control inflammation inside the brain

Inside the brain, a protein called YAP, best known for its ability to help right-size our developing hearts and livers, appears to have the different but equally important task of helping control inflammation.

23 Dec 2015

Perisylvian polymicrogyria gene found

Researchers have identified the genetic basis for bilateral perisylvian polymicrogyria, the most common form of regional polymicrogyria.

4 Nov 2015

Codman Neuro develops new MRI-resistant programmable valve for treatment of hydrocephalus

Codman Neuro* has developed a new MRI-resistant programmable valve with eight different pressure settings, including a ‘virtual off’ setting, for the treatment of hydrocephalus, a neurological condition that affects more than one million children and adults in the United States.

22 Sep 2015

Fetuses with enlarged ventricles are not ideal candidates for fetal spina bifida surgery

Fetuses with enlarged ventricles--the fluid-filled cavities inside the brain--may be less likely than other fetuses to benefit from surgery in the womb to treat spina bifida, according to a study co-authored by researchers at UCSF Benioff Children's Hospital San Francisco.

16 Sep 2015

Prenatal repair of myelomeningocele reduces need for CSF shunt within 12 months of life, shows MOMS data

Management of Myelomeningocele Study (MOMS) investigators analyzed updated data on the effects of prenatal myelomeningocele closure on the need for placement of a cerebrospinal fluid (CSF) shunt within the first 12 months of life.

15 Sep 2015

Promising research aims at finding cure for hydrocephalus

Scientists are focusing in on promising research aimed at finding a cure for hydrocephalus; and a new initiative funded by the Hydrocephalus Association, the largest private funder of hydrocephalus research in the United States, is uniting these researchers to accelerate their progress.

27 Aug 2015

Obstructive hydrocephalus produces significant decrease in brain neurogenesis

In a group of mice, has been identified that their brain presents degenerative changes similar to aging after two months that their cerebrospinal fluid (CSF) stopped circulating normally within the body and starts to accumulate, as reported by a Mexican group of researchers at the University of Colima.

18 Aug 2015

Nuclear process in the brain may play critical role in health and disease

Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped brain cell, called an astrocyte, may play a critical role in health and disease.

18 Aug 2015

UT Arlington, UNTHSC scientists to build prototype for implantable shunt flow monitoring system

Scientists from The University of Texas at Arlington and the University of North Texas Health Science Center are building a prototype for an implantable in-line shunt flow monitoring system that would deliver both on-demand and continuous readings of hydrocephalus.

8 Jul 2015

Commercially available headphones unlikely to interfere with programmable shunt valve settings

Researchers at Brown University examined three magnetically programmable shunt valves to see if the magnetic field emissions of headphones can cause unintentional changes in shunt valve settings. Based on their findings, the researchers state that it is highly unlikely that commercially available headphones will interfere with programmable shunt valve settings.

7 Jul 2015

OhioHealth Neuroscience Center launched at Riverside Methodist Hospital

On July 6, 2015, OhioHealth will open its doors to the new OhioHealth Neuroscience Center on Riverside Methodist Hospital's campus.

25 Jun 2015