Hydroxychloroquine News and Research

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New oligomer shows promising anti-SARS-CoV-2 properties

Scientists from the University Of New Mexico have recently identified a new cationic oligomer that may help inactivate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Oct 2021

Key lessons from COVID-19 pandemic for scientific and clinical communities

In a paper published in the journal Cell, researchers have investigated and criticized clinical care management and drug administration within the pandemic.

4 Oct 2021

Dispensing of hydroxychloroquine and ivermectin in Australia jumped in first year of COVID

A new study describes the nature and extent of the shift in dispensing these medications, as well as its eventual outcome.

3 Oct 2021

Greater viral load of SARS-CoV-2 variants of concern increases transmission potential

By quantifying the probability of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in accordance with its viral load after a high-risk contact, researchers from France, Spain, and the United Kingdom show a substantial correlation of transmission probability and viral load increase in variants of concern.

28 Sep 2021

WHO experts recommend antibody treatment for two specific groups of patients with covid-19

A treatment combining two antibodies (casirivimab and imdevimab) is recommended for two specific groups of patients with covid-19 by a WHO Guideline Development Group (GDG) panel of international experts and patients in The BMJ today.

24 Sep 2021

Potential covalent SARS-CoV-2 spike protein inhibitors

There remains a significant need for new and effective drugs that can be used to treat COVID-19.

23 Sep 2021

Will ‘Dr. Disinformation’ ever face the music?

Earlier this month, Dr. Rashid Buttar posted on Twitter that covid-19 "was a planned operation" and shared an article alleging that most people who got the covid vaccine would be dead by 2025.

22 Sep 2021

Severe tinnitus following SARS-CoV-2 infection

A 49-year-old male with a history of COVID-19 presents with tinnitus.

21 Sep 2021

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

In a recent study, scientists attempt to understand persistent COVID-19 and its implications in patients with hematologic malignancies.

6 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

New evidence provides strong support for the halt on prescribing hydroxychloroquine for COVID-19

In 2021, in the United States alone, there have been more than 560,000 prescriptions of hydroxychloroquine for the prevention, post-exposure and treatment of COVID-19.

31 Aug 2021

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

A new study has explored a series of potential flavonoid inhibitors targeting 3CL protease of SARS-CoV.

9 Aug 2021

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Niclosamide is an antihelminthic drug, historically used to treat tapeworm infestations, though has been investigated and repurposed for use against SARS-CoV-2. In a new study recently uploaded to the preprint server bioRxiv* by Garrett et al. (July 12, 2021), the drug demonstrates the ability to reorganize the lipid profile of SARS-CoV-2 infected Vero E6 cells, thereby limiting virus replication.

14 Jul 2021

Molecular dynamic analysis of SARS-CoV-2 inhibitors

A new study reports the results of molecular dynamic simulations that were performed in an effort to identify new drugs that could be effective against SARS-CoV-2.

13 Jul 2021

Anti-rheumatic drug combinations could reduce the risk of heart attack and strokes

New research evaluating the drugs commonly used by rheumatoid arthritis patients suggests two combinations could reduce the risk of heart attack and strokes.

6 Jul 2021

What are predictive biomarkers of COVID-19 disease severity in pregnant women?

In a paper recently published in the Nature journal Scientific Reports, a retrospective cohort study on inflammatory biomarkers in pregnant women with COVID-19 reveals key differences that could better allow an accurate COVID-19 prognosis to be attained in pregnant women.

5 Jul 2021

Anti-malarial drug shows promise in the battle against COVID-19

In the "war" that the world has been fighting against COVID-19, scientists have been scanning their arsenals of previously used drugs in hopes of finding any that can be used to treat the disease.

1 Jul 2021

Researchers design a smart device that delivers medications to prevent HIV transmission

Researchers have designed a device that delivers two medications that help stop HIV transmission.

18 Jun 2021

What is the role of monoclonal antibody therapy in treating COVID-19?

A new study has been published in the journal Vaccines that deals with the present state of research on using mAbs for the treatment of the COVID-19 disease. Many clinical trials are being conducted to evaluate the efficacy and safety of several newly designed mAbs. Some of the mAbs are directed towards immune system responses, i.e., non-SARS-CoV-2 specific mAbs, while others are devised to neutralize the SARS-CoV-2 protein structure, i.e., SARS-CoV-2 specific mAbs.

8 Jun 2021

The great promise of antiviral peptides against SARS-CoV-2

A new study, recently published in the journal Viruses, describes the impressive evidence for the role of antimicrobial peptidse (AMPs) in the treatment of COVID-19.

7 Jun 2021