Hyperlipidemia News and Research

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Hyperlipidemia, hyperlipoproteinemia or dyslipidemia is the presence of raised or abnormal levels of lipids and/or lipoproteins in the blood. Lipids (fatty molecules) are transported in a protein capsule, and the density of the lipids and type of protein determines the fate of the particle and its influence on metabolism.

Grapefruits help reduce cholesterol

A grapefruit a day - particularly the red variety - can help keep heart disease at bay, according to a new study by Israeli researchers.

16 Feb 2006

Grapefruit reduces risk from heart disease

Heart disease patients who eat one grapefruit daily can significantly reduce the levels of cholesterol in their blood in comparison to patients who do not eat the fruit, a new study has found. Chronic high blood cholesterol is a major risk factor for heart disease.

16 Feb 2006

Impotence may provide a warning sign of coronary heart disease

Erectile dysfunction may provide a warning sign of significant coronary heart disease researchers from the University of Chicago report in the January 23 issue of the Archives of Internal Medicine.

23 Jan 2006

Greater use of evidence-based medicine needed in US outpatient care

Although the quality of outpatient care in the United States has improved over the last decade, greater use of evidence-based medicine is needed, however, and quality of care is not significantly associated with the patient's racial or ethnic background, according to a study in the June 27 issue of Archives of Internal Medicine.

27 Jun 2005

Metabasis and Merck collaborate to develop new treatment for diabetes, hyperlipidemia and obesity

Metabasis Therapeutics and Merck announced today that they have formed a collaboration to research, develop and commercialize novel small molecule therapeutics with potential to treat several diseases, including type II diabetes, hyperlipidemia and obesity, by activation of an enzyme in the liver called AMP-activated Protein Kinase (AMPK).

27 Jun 2005

Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents, compared with placebo, according to an article in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Metabolic syndrome linked to testosterone deficiency

Among men studied, those with a history of diabetes, hypertension or hyperlipidemia have a higher prevalence of hypogonadism, according to new research issued today at the American Association of Clinical Endocrinologists (AACE) Fourteenth Annual Meeting and Clinical Congress.

18 May 2005

Targeted Genetics announces new patent for Hyperlipidemia

Targeted Genetics Corporation announced today issuance of U.S. patent #6,887,463, entitled, "Methods and Compositions for Gene Therapy for the Treatment of Defects in Lipoprotein Metabolism."

11 May 2005

Risk scores may identify young individuals with atherosclerosis

Young people with atherosclerotic lesions may be identified by a risk score calculated from coronary heart disease factors like obesity, sex, age, cholesterol, and smoking, according to an article in the April 25 issue of Archives of Internal Medicine.

25 Apr 2005

Modest triglyceride elevations linked to coronary artery disease risk

Even modest increases in blood levels of triglycerides, as well as a type of high cholesterol known as type III hyperlipidemia, are strongly associated with coronary artery disease in people with a family history of the disease, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Alteration of steroid receptor genes creates fat burning muscle

The Salk Institute scientist who earlier discovered that enhancing the function of a single protein produced a mouse with an innate resistance to weight gain and the ability to run a mile without stopping has found new evidence that this protein and a related protein play central roles in the body's complex journey to obesity and offer a new and specific metabolic approach to the treatment of obesity related disease such as Syndrome X (insulin resistance, hyperlipidemia and atherosclerosis).

4 Apr 2005

New trial for treatment of liver disease

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network is launching its first two clinical trials for the study of NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol.

3 Apr 2005

HIV is not an independent risk factor for severe heart disease

Infection with human immunodeficiency virus (HIV) is no longer an automatic death sentence, thanks to the use of highly active anti-retroviral therapy (HAART).

8 Mar 2005

Risks of obesity in children with kidney transplants

Obese children who get kidney transplants tend to be younger, shorter and on dialysis longer than their leaner peers, according to a study in the February issue of the journal Pediatrics.

7 Feb 2005

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

The prevalence of the disease varied significantly among ethnic groups. Hispanics had a higher prevalence than whites, while blacks had a lower prevalence than whites.

8 Dec 2004

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

Results from a new study showed that coadministration of Zetia (ezetimibe) and fenofibrate significantly reduced LDL ("bad") cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C) and apo B1 in patients with mixed hyperlipidemia and high LDL cholesterol when compared to fenofibrate alone.

9 Nov 2004

Weight loss surgery reduces components of metabolic syndrome in obese patients

Obese patients who underwent surgical treatment for weight loss had significant reductions in the components of the metabolic syndrome one year after surgery, according to an article in the October issue of The Archives of Surgery.

18 Oct 2004

Surgical treatment for morbid obesity helps prevent hyperlipidemia, hypertension, and obstructive sleep apnea

A summary of data from numerous studies suggests that the majority of morbidly obese patients who underwent bariatric (obesity) surgery experienced effective weight loss and improvement in diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea, according to an article in the October 13 issue of JAMA.

12 Oct 2004

Ezetrol co-administration with statin therapy lowers LDL cholesterol in diabetics

Results from two new clinical trials show that patients with diabetes and metabolic syndrome who are treated with ezetimibe (EZETROL®) co-administered with a statin experience greater reductions in LDL (“bad”) cholesterol, compared to patients taking a statin alone.

7 Sep 2004

Sugar Association questions claim that breast cancer is connected to sucrose consumption

In response to a recent study published in the journal "Cancer Epidemiology, Biomarkers and Prevention," the Sugar Association is questioning the study's claim that breast cancer is connected to sucrose consumption.

11 Aug 2004