Hypoxemia News and Research

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Hypoxemia (or Hypoxaemia) is generally defined as decreased partial pressure of oxygen in blood, sometimes specifically as less than which, without further specification, would include both concentration of dissolved oxygen and oxygen bound to hemoglobin.

GLUMETZA tablets are now available to wholesalers and physicians

Santarus, and Depomed, today announced that supply of GLUMETZA® 500 mg to wholesalers and retailers has resumed. GLUMETZA is a once-daily, extended release formulation of metformin and is approved for use in adults with type 2 diabetes mellitus.

5 Jan 2011

Researchers find structural deficits in gray matter may be associated with daytime sleepiness

Patients with obstructive sleep apnea (OSA) may blame their daytime difficulties on simple sleepiness, but new research suggests that their brains may be to blame. Specifically, their cognitive challenges may be caused by structural deficits in gray matter, brought on by the intermittent oxygen deprivation that comes with OSA. The good news is that these deficits may be partially or fully reversible with early detection and treatment, according to Italian researchers

15 Nov 2010

OrSense's NBM 200MP non-invasive Hb measurement system more accurate than invasive POC devices

OrSense Ltd., developer of monitors for non-invasive measurements of various blood parameters, presented in an oral presentation at the American Society of Anesthesiologists (ASA) annual meeting in San Diego, results showing that hemoglobin (Hb) measurements obtained by its NBM 200MP, a non-invasive Hb measurement system, showed accurate performance during hemorrhage conditions compared with invasive point of care (POC) devices.

18 Oct 2010

Alkermes' VIVITROL medication for treatment of opioid dependence

Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved VIVITROL(naltrexone for extended-release injectable suspension) for the prevention of relapse to opioid dependence, following opioid detoxification.

13 Oct 2010

FDA Advisory Committee recommends approval of Alkermes' VIVITROL for opioid dependence

Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee voted 12 to 1 that VIVITROL® (naltrexone for extended-release injectable suspension) should be approved for the treatment of opioid dependence.

17 Sep 2010

Ikaria announces voluntary recall of INOMAX DS drug-delivery system in US and Canada

Ikaria, Inc. announced today that its INOMAX® DS drug-delivery systems in the United States are being voluntarily recalled due to the potential failure of a pressure switch which may have an impact on the administration of INOMAX® (nitric oxide) for inhalation to patients. This potential failure was identified by Ikaria as part of its ongoing quality monitoring and review processes. This class I recall is being conducted with the knowledge of the U.S. Food and Drug Administration (FDA). All INOMAX DS systems in Canada also are being voluntarily recalled.

10 Aug 2010

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

New data were presented at the American Diabetes Association 70th Annual Scientific Sessions from a study comparing JANUMET (sitagliptin/metformin) to pioglitazone. In this study, JANUMET resulted in significantly greater blood sugar reductions in patients with type 2 diabetes compared with pioglitazone.

28 Jun 2010

Alkermes receives tentative schedule notification for FDA advisory committee meeting on VIVITROL sNDA

Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has notified the company of the tentative scheduling of a Psychopharmacologic Drugs Advisory Committee meeting on September 16, 2010, for the review of the company's supplemental New Drug Application (sNDA) for VIVITROL® (naltrexone for extended-release injectable suspension) for opioid dependence.

18 Jun 2010

Studies show positive effects of CPAP on cardiovascular incidence in non-sleepy OSA patients

In non-sleepy patients with obstructive sleep apnea, treatment with continuous positive airway pressure can reduce the incidence of cardiovascular events and hypertension, according to researchers from Spain.

20 May 2010

Human stem cells restore alveolar epithelial tissue after E. coli endotoxin-induced ALI: Researchers

Human stem cells administered intravenously can restore alveolar epithelial tissue to a normal function in a novel ex vivo perfused human lung after E. coli endotoxin-induced acute lung injury, according to research from the University of California San Francisco.

18 May 2010

Adults with SCA show poorer performance on neurocognitive tests: Study

Compared with a group of healthy study participants, adults with sickle cell anemia showed poorer performance on neurocognitive tests, which was associated with anemia and age, according to a study in the May 12 issue of JAMA.

13 May 2010

High-altitude exposure helps detect early vascular dysfunction

High altitude medicine is a "natural research laboratory" for the study of cardiovascular physiology and pathophysiology. As such, it can shed light on conditions and diseases that mimic the low oxygen content of the atmosphere at the top of mountains. Yves Allemann, MD, FESC, Swiss Cardiovascular Center, University Hospital, Bern, and Urs Scherrer, MD, Centre Hospitalier Universitaire Vaudois, Lausanne, have assembled an international group of leading authorities to contribute to a special issue of Progress in Cardiovascular Diseases.

5 May 2010

Six abstracts featuring FORE-SIGHT system presented at Pediatric Academic Societies meeting

CAS Medical Systems, Inc. today announced that six abstracts featuring the use of the FORE-SIGHT Absolute Oximeter were presented at the Pediatric Academic Societies meeting May 1-4 in Vancouver, BC, Canada. This meeting includes more than 7,500 leaders in academic pediatrics and is dedicated to the advancement of pediatric research and the advanced care of acutely ill children.

5 May 2010

Special issue of Progress in Cardiovascular Diseases

5 May 2010

Propofol is safe for endoscopic procedures with low rate of sedation-related adverse events: Study

Propofol is safe for advanced endoscopic procedures with a low rate of sedation-related adverse events when administered by a trained professional, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association Institute.

4 Mar 2010

Hospitalization may be a marker for cognitive decline or dementia in older patients, says study

Older patients hospitalized for acute care or a critical illness are more likely to experience cognitive decline compared to older adults who are not hospitalized, according to a study in the February 24 issue of JAMA.

24 Feb 2010

Study assesses gray matter concentration deficits in multiple brain areas of people with OSA

A study in the Feb. 1 issue of the journal SLEEP found gray matter concentration deficits in multiple brain areas of people with severe obstructive sleep apnea (OSA). The study suggests that the memory impairment, cardiovascular disturbances, executive dysfunctions, and dysregulation of autonomic and respiratory control frequently observed in OSA patients may be related to morphological changes in brain structure.

1 Feb 2010

Nonanesthesiologist-administered propofol for GI procedures safe

The worldwide safety experience of endoscopist-administered propofol sedation now exceeds 600,000 patients. The low rate of serious adverse events underscores the safety of nonanesthesiologist-administered propofol (NAAP) for gastrointestinal (GI) procedures, provided that it is administered by a team of individuals who have received training specific to the administration of propofol according to the "Position statement: nonanesthesiologist administration of propofol for GI endoscopy" issued by the four major gastroenterology and hepatology societies.

3 Dec 2009

Mechanical ventilation damages lungs, says scientist

As more Canadians are diagnosed with H1N1 influenza infection, some will be admitted to hospital. The most severely affected may be treated in the intensive care unit (ICU) and placed on a mechanical ventilator to help them breathe while they recover from the infection.

13 Nov 2009

Prone ventilation for ARDS patients does not lower mortality rate, says new study

Despite a current suggestion that patients with acute respiratory distress syndrome be positioned lying face down while receiving mechanical ventilation, study results indicate that this positioning does not significantly lower the risk of death compared to similar patients positioned lying face up during ventilation, according to a study in the November 11 issue of JAMA.

11 Nov 2009

Hypoxemia News and Research

Further Reading

GLUMETZA tablets are now available to wholesalers and physicians

Researchers find structural deficits in gray matter may be associated with daytime sleepiness

OrSense's NBM 200MP non-invasive Hb measurement system more accurate than invasive POC devices

Alkermes' VIVITROL medication for treatment of opioid dependence

FDA Advisory Committee recommends approval of Alkermes' VIVITROL for opioid dependence

Ikaria announces voluntary recall of INOMAX DS drug-delivery system in US and Canada

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

Alkermes receives tentative schedule notification for FDA advisory committee meeting on VIVITROL sNDA

Studies show positive effects of CPAP on cardiovascular incidence in non-sleepy OSA patients

Human stem cells restore alveolar epithelial tissue after E. coli endotoxin-induced ALI: Researchers

Adults with SCA show poorer performance on neurocognitive tests: Study

High-altitude exposure helps detect early vascular dysfunction

Six abstracts featuring FORE-SIGHT system presented at Pediatric Academic Societies meeting

Special issue of Progress in Cardiovascular Diseases

Propofol is safe for endoscopic procedures with low rate of sedation-related adverse events: Study

Hospitalization may be a marker for cognitive decline or dementia in older patients, says study

Study assesses gray matter concentration deficits in multiple brain areas of people with OSA

Nonanesthesiologist-administered propofol for GI procedures safe

Mechanical ventilation damages lungs, says scientist

Prone ventilation for ARDS patients does not lower mortality rate, says new study

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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