Imaging News and Research

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Fluorine-based nanoparticles on track to improve cancer detection and therapy

Perfluorocarbons, a class of inert, oily polymers, have a proven track record in a variety of clinical uses, including in contrast-enhanced ultrasound imaging and in eye surgery to correct a detached retina.

18 Apr 2008

Nanoparticles provide detailed view inside living animals

Using nanoparticles designed specifically to produce a bright Raman spectroscopic signal, a team of investigators at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (Stanford CCNE) has shown that it can produce whole-body images in small animals that can reveal the location of tumors and track how these nanoparticles traffic through the body.

18 Apr 2008

Quantum rods light up pancreatic cancer cells

Quantum dots have shown promise as ultrabright contrast agents for use in a variety of cancer imaging studies. Now, a team of investigators at the Multifunctional Nanoparticles in Diagnosis and Therapy of Pancreatic Cancer Platform Partnership, headed by Paras Prasad, Ph.D., of the State University of New York at Buffalo, has shown that quantum rods may perform even better than their spherical cousins.

18 Apr 2008

Iron nanoparticles spot tumor spread in patients with kidney cancer

Iron nanoparticles designed to collect in lymph nodes containing metastatic cancer cells have proven that they can help physicians detect metastatic spread of prostate cancer.

18 Apr 2008

Novel polymers inhibit nonspecific protein absorption

One problem that confounds researchers who are developing nanoparticles for use as cancer imaging and therapeutic agents is that many nanoparticles accumulate blood proteins on their surfaces as they circulate through the body.

18 Apr 2008

Life Sciences Discovery Fund awards $2.2 million to support new solid-tumor research program

The state's Life Sciences Discovery fund has awarded $2.2 million to establish a formal phase 1 clinical-trials program to test new therapies for solid tumors at Fred Hutchinson Cancer Research Center. Announced this evening, the grant is among the first funded by Washington's $350 million tobacco-lawsuit-settlement bonus.

17 Apr 2008

New insights on early Parkinson's provided by advanced MRI

Parkinson's disease is a degenerative disorder of the brain affecting movement, speech, mood, behavior, thinking and sensation for which there is no known cause or cure.

17 Apr 2008

Measurement technology to investigate neurovascular coupling

Every two minutes in Germany, one person suffers a stroke. About one third of the affected do not survive the sudden lack of blood in the brain, many others are left with serious disabilities.

17 Apr 2008

New drug for melanoma riluzole shows promise

Rutgers Professor Suzie Chen has found that riluzole, a U.S. Food and Drug Administration (FDA) approved drug used to treat Lou Gehrig's disease (ALS), slows the growth of melanoma, the most aggressive form of malignant skin cancer.

16 Apr 2008

Elevated levels of antioxidant urate may slow Parkinson's progression

Naturally elevated levels of the antioxidant urate may slow the progression of Parkinson's disease in men. Researchers from the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) and Harvard School of Public Health (HSPH) examined data from an earlier study and found that, among recently diagnosed Parkinson's patients, those with the highest urate levels had a significantly slower rate of disease progression during the two-year study period.

15 Apr 2008

Best use for popular CAD assessment procedure is misunderstood

What is the best way to determine if you are developing the nation's most deadly condition, coronary artery disease (CAD)?

15 Apr 2008

Some kids with autism may have a genetic defect that affects the muscles

...according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008.

13 Apr 2008

Patient's exposure to radiation significantly lower when using prospective gated 64-channel cardiac CT

A new cardiac CT technique, prospective gated 64-channel cardiac CT, has a significantly lower radiation dose and produces CT coronary angiograms with better image quality when compared with the standard retrospective ECG gating, according to a recent study conducted by researchers at the University of Washington in Redmond, WA.

11 Apr 2008

MRI and PET/CT can prevent unnecessary treatment of some cervical cancer patients

MRI and PET/CT can help spare patients with clinically operable cervical cancer from unnecessary high-morbidity treatment, however, pretreatment imaging does not lead to increased survival of these patients, a new study shows.

11 Apr 2008

Mammography and sonography used together can help rule out breast cancer in patients with palpable lesions

When mammography and sonography are used together to evaluate palpable breast lesions, they can rule out cancers in most patients, according to a recent study conducted by researchers at Baystate Health in Springfield, MA. However, uncommonly, malignancies cannot be diagnosed using this imaging protocol.

11 Apr 2008

Impairments in language development can be detected in infants as young as 3 months

Uncover how the brains of infants distinguish differences in sounds and it may become possible to correct language problems even before children start to speak, sparing them the difficulties that come from struggling with language.

11 Apr 2008

Biomarkers may reduce the need for biopsies and personalize transplant patient care

Data presented at the 28th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) suggest the potential of a significant impact of using biomarkers to reduce the need for biopsies and personalize transplant patient care.

11 Apr 2008