Immune Response News and Research

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Psychological stress linked to higher risk of cancer-specific mortality in cervical cancer patients

Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer.

1 Aug 2019

Researchers discover SIGN-R1 molecule that recognizes multiple variants of influenza

A team of researchers from the Institute for Research in Biomedicine (IRB, affiliated to USI Università della Svizzera italiana, Switzerland) have discovered and identified a molecule - SIGN-R1 - capable of recognizing the multiple variants of influenza and consequently 'directing' the immune response in individuals affected by the disease.

30 Jul 2019

Gut bacteria that prevents mice from becoming obese may also control weight in people

Researchers at University of Utah Health have identified a specific class of bacteria from the gut that prevents mice from becoming obese, suggesting these same microbes may similarly control weight in people.

26 Jul 2019

Researchers demonstrate positive and negative role of LRH-1 during inflammation

Immune cells prevent bacteria, parasites or viruses from entering the body when, for example, the intestinal epithelium is injured.

26 Jul 2019

Nanoparticles foster regenerative healing process after spinal cord injury

Paralyzing damage in spinal cord injury is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.

25 Jul 2019

New vaccine shows promise against toughest HIV strains

A new study reports successful immunization against a so-far invincible “death star” strain of an HIV-related laboratory virus (SIVmac239) and another tough strain. The new approach also achieves long-term protection with a single dose, showing that gene therapy could allow broad and durable protection, based on a modified form of the CD4 protein that allows HIV entry into human cells.

24 Jul 2019

Algorithm based on ‘first impressions’ of immune cells may help predict onset of diseases

First impressions are important – they can set the stage for the entire course of a relationship. The same is true for the impressions the cells of our immune system form when they first meet a new bacterium.

24 Jul 2019

Novel sensor could accelerate diagnosis of sepsis

A novel sensor designed by MIT researchers could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually.

24 Jul 2019

Evolutionary gene loss may explain heightened risk of cardiovascular disease in humans

Researchers at University of California San Diego School of Medicine say the loss of a single gene two to three million years ago in our ancestors may have resulted in a heightened risk of cardiovascular disease in all humans as a species, while also setting up a further risk for red meat-eating humans.

23 Jul 2019

Researchers identify genes linked to death from sepsis in mice

Sepsis is a life-threatening condition that occurs when the body's immune response to infection spirals out of control.

23 Jul 2019

Researchers identify encephalitis as rare toxicity of immunotherapy treatment

After a cancer patient receiving an immunotherapy developed encephalitis and died 18 months into treatment, researchers at Vanderbilt-Ingram Cancer Center investigated why the complication occurred, performing a molecular analysis of the disease's pathology and mining data to determine the incidence of similar occurrences.

22 Jul 2019

New technology helps develop more personalized treatments for patients with advanced cancers

Being able to identify targets for adoptive cell therapies is one of the first steps in developing personalized treatments for people with hard-to-treat cancers.

22 Jul 2019

Disruption of immune cell behavior may spur heart disease, heart failure

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie.

From Johns Hopkins Medicine 19 Jul 2019

Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

Receptor in the uterus can detect sperm molecule, aids in sperm survival

Why does it take 200 million sperms to fertilize a single egg? The single sperm that reached the finished line has successfully survived multiple checkpoints within the female reproductive tract, dubbed as pre-fertilization events. Now, a new study shows that the uterus contains receptors that facilitate sperm survival.

19 Jul 2019

Gut infection can lead to a pathology resembling Parkinson's disease

A new study by Montreal scientists published today in Nature demonstrates that a gut infection can lead to a pathology resembling Parkinson's disease in a mouse model lacking a gene linked to the human disease.

17 Jul 2019

Women's greater immune response to flu vaccine declines with age

Women tend to have a greater immune response to a flu vaccination compared to men, but their advantage largely disappears as they age and their estrogen levels decline, suggests a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

17 Jul 2019

Novel vaccine against bee sting allergy successfully tested

A recently completed trial on a bee sting vaccine containing a novel adjuvant called Advax to increase its efficacy has raised hopes that severe allergic reactions, sometimes fatal, to bee venom in allergic people could soon be a thing of the past. The vaccine was designed to neutralize the venom of the European honeybee.

17 Jul 2019

Researchers find mechanism behind susceptibility to viral infections

A team of researchers from the SingHealth Duke-NUS Academic Medicine Centre's Viral Research and Experimental Medicine Centre found that immune cells undergoing stress and an altered metabolism are the reasons why some individuals become sick from viral infections while others do not, when exposed to the same virus.

16 Jul 2019

Gut microbiota protects from viral-induced neurologic damage, study finds

Gut microbes produce compounds that prime immune cells to destroy harmful viruses in the brain and nervous system, according to a mouse study published today in eLife.

16 Jul 2019