Immune Response News and Research

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Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years - and 25% of patients whose tumor cells had a specific protein lived at least that long.

3 Jun 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

A team of researchers led by Kazuhiro Suzuki from the Immunology Frontier Research Center at Osaka University discovered the COMMD3/8 complex as a molecule involved in immune cell migration, clarifying that the complex plays a critical role in the establishment of immune responses.

31 May 2019

Researchers find new molecular targets for fighting autoimmunity

BRCA--the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers--interacts with a multipart, molecular complex that is also responsible for regulating the immune system.

30 May 2019

Newly identified internal regulator helps control body's response to fight infection

Scientists have identified a new internal regulator which helps control the body's response to fight infection.

30 May 2019

Researchers develop a standardized method for predicting transplant rejection

Researchers from The Westmead Institute for Medical Research have developed a standardized method of measuring the immune response in islet transplant recipients, helping predict patient outcomes.

29 May 2019

Study: Immune discovery may improve cancer therapies

Cancer therapies that use immune cells to trigger the body to attack tumors could be improved by a molecule that boosts their function.

29 May 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Findings provide new insights about how intestine maximizes nutrient uptake

As food enters the intestine, it embarks on windy, lengthy journey. For most of the route, its surroundings don't appear to change much.

25 May 2019

EU-funded project works to better understand human and parasite interactions

Whipworms are parasitic roundworms that live preferentially in the human cecum, the blind pouch at the beginning of the large intestine. They tunnel through epithelial cells and cause inflammation, potentially resulting in trichuriasis, an infection similar to colitis.

23 May 2019

NIAID announces two awards for the study of influenza immunity in kids

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has announced two awards for the study of influenza immunity in children.

23 May 2019

Scientists identify target to ‘tone down’ hyper-active immunity to influenza infection

For most people, the influenza A virus, commonly known as the flu, is cleared from the body by our own immune system.

23 May 2019

Study may explain mystery of long-term parasitic infections

As hosting gigs go, it's a tough crowd. More than 1 billion people are host to parasitic worms that take up residence in their intestines. For most, it's a short stay, with the immune system evicting the worms in days or weeks and leaving no trace that the parasites were ever there.

22 May 2019

Immunotherapy is the most prominent topic in skin cancer research, report reveals

A new report published today highlights the different research areas in the field of skin cancer, showing that immunotherapy is the most prominent topic and reveals the countries that are driving this research.

21 May 2019

Researchers discuss how time of day affects the severity of illness

In a review published May 17 in the journal Trends in Immunology, researchers discuss how time of day affects the severity of afflictions ranging from allergies to heart attacks.

21 May 2019

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.

21 May 2019

Immune Response News and Research

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

Scientific discovery may lead to a treatment for lupus

Researchers discover COMMD3/8 protein complex as molecule involved in immune cell migration

Researchers find new molecular targets for fighting autoimmunity

Newly identified internal regulator helps control body's response to fight infection

Researchers develop a standardized method for predicting transplant rejection

Study: Immune discovery may improve cancer therapies

Research could lead to new treatments for people with autoimmune disorders

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Findings provide new insights about how intestine maximizes nutrient uptake

EU-funded project works to better understand human and parasite interactions

NIAID announces two awards for the study of influenza immunity in kids

Scientists identify target to ‘tone down’ hyper-active immunity to influenza infection

Study may explain mystery of long-term parasitic infections

Immunotherapy is the most prominent topic in skin cancer research, report reveals

Researchers discuss how time of day affects the severity of illness

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Circadian rhythm influences immune responses across a range of diseases

Study explains why several clinical trials of treatments for sepsis have been failed

University of Virginia chemist identifies potential addiction-free pain reliever

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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