Immune Response News and Research

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Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

New immunoregulatory protein linked to autoimmune disease

Autoimmune diseases are complex illnesses, the causes of which are diverse and have not yet been fully explained.

18 Sep 2023

NIH launches Phase 1 trial of new investigational universal influenza vaccine

Enrollment in a Phase 1 trial of a new investigational universal influenza vaccine candidate has begun at the National Institutes of Health's Clinical Center in Bethesda, Maryland.

15 Sep 2023

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Shared genetic markers and immune system involvement in sJRA and T1D.

15 Sep 2023

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

MIT study reveals why immunotherapy doesn't work for all cancer patients

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14 Sep 2023

UKHSA's flagship SIREN study enters new phase to continue surveillance of respiratory pathogens

The next phase of the study will be known as SIREN 2.0 and began in September 2023.

14 Sep 2023

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Patients with stage 1–3 non-small cell lung cancer (NSCLC) given a combination immunotherapy prior to surgery (neoadjuvant) had a better major pathological response (10% or less residual cancer) when the cancer was removed than those who took a single immunotherapy agent alone, according to results of a novel multicenter phase 2 NeoCOAST platform trial that included two investigators from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy.

14 Sep 2023

Unhealthy pathobiome in the brain could cause some forms of Alzheimer's and related dementias

The human microbiome includes the genetic material of more than 100 trillion tiny microorganisms – fungi, yeast, bacteria, and even viruses, most of which hang out in our gastrointestinal tract to serve as guardians of our health.

13 Sep 2023

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops.

13 Sep 2023

Why the CDC has recommended new covid boosters for all

Everyone over the age of 6 months should get the latest covid-19 booster, a federal expert panel recommended Tuesday after hearing an estimate that universal vaccination could prevent 100,000 more hospitalizations each year than if only the elderly were vaccinated.

13 Sep 2023

Herring roe oil's potential in psoriasis treatment

Researchers investigated the use of herring row oil to treat psoriasis, a non-communicable skin disease.

12 Sep 2023

“Inverse vaccine” shows promise to reverse autoimmune diseases without shutting down rest of the immune system

A new type of vaccine developed by researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) has shown in the lab setting that it can completely reverse autoimmune diseases like multiple sclerosis, type 1 diabetes, and Crohn's disease -; all without shutting down the rest of the immune system.

12 Sep 2023

Scientists develop new method to detect key fat-filled particles in the brain

Scientists have created a method to detect key fat-filled particles known as lipoproteins in the central nervous system, opening a new view into the workings of the brain.

12 Sep 2023

The safety and efficacy of the nano-based COVID-19 vaccine

A recent study evaluated the safety and efficacy of the GBP510 vaccine against SARS-CoV-2 infection.

12 Sep 2023

Mature gut microbiota in early infancy may protect against wheezing and allergies

Babies and young children with more mature communities of bacteria present in their gut are less likely to develop allergy-related wheezing or asthma, according to research presented at the European Respiratory Society International Congress in Milan, Italy.

11 Sep 2023

Unlocking the secrets of our body's first line of defense against strep throat and more

Researchers have mapped the complex structures of secretory immunoglobulin A (sIgA) in interaction with human CD89 and Streptococcus pyogenes M4, offering new insights into how our first line of mucosal defense operates. The study reveals the intricate ways these components may influence each other, impacting both bacterial survival strategies and host immune responses.

10 Sep 2023

Self-adjuvanting RNA vaccines boost immune response 10x more than existing vaccines

RNA vaccines against Covid-19 have proven effective at reducing the severity of disease. However, a team of researchers at MIT is working on making them even better.

8 Sep 2023

Is your body clock the secret to peak athletic performance?

Review comprehensively explores how the circadian rhythm impacts sports performance, hormonal regulation, and immune system function in athletes. The study emphasizes the optimal times of day for athletic performance and underlines the role of circadian rhythm in hormonal balance and immune responses.

7 Sep 2023

Study unveils a potential solution to combat age-related immune system decline

As we age, our bodies face numerous challenges, including a decline in immune system function and an increased vulnerability to various health issues.

7 Sep 2023

Immune Response News and Research

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

New immunoregulatory protein linked to autoimmune disease

NIH launches Phase 1 trial of new investigational universal influenza vaccine

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

MIT study reveals why immunotherapy doesn't work for all cancer patients

UKHSA's flagship SIREN study enters new phase to continue surveillance of respiratory pathogens

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Unhealthy pathobiome in the brain could cause some forms of Alzheimer's and related dementias

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

Why the CDC has recommended new covid boosters for all

Herring roe oil's potential in psoriasis treatment

“Inverse vaccine” shows promise to reverse autoimmune diseases without shutting down rest of the immune system

Scientists develop new method to detect key fat-filled particles in the brain

The safety and efficacy of the nano-based COVID-19 vaccine

Mature gut microbiota in early infancy may protect against wheezing and allergies

Unlocking the secrets of our body's first line of defense against strep throat and more

Self-adjuvanting RNA vaccines boost immune response 10x more than existing vaccines

Is your body clock the secret to peak athletic performance?

Study unveils a potential solution to combat age-related immune system decline

Breaking Barriers: ANDYSMANCLUB's Fight for Men's Mental Health on World Mental Health Day

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

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