Immune Response News and Research

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Olive oil-based emulsion shows promise for mycobacterial treatment of bladder cancer

Researchers at the Universitat Autònoma de Barcelona with the collaboration of the Institute for Bioengineering of Catalonia, led by the professor of the UAB Department of Genetics and Microbiology Esther Julián, announced one year ago that the cells of the Mycobacterium brumae offer an improved alternative to current bladder cancer treatments such as BCG (an immunotherapy based on the Mycobacterium bovis), which can cause infections.

23 Jun 2016

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Researchers from the University of Chicago have shown that microbiota—the bacteria, viruses and other microbes living on the skin and in the digestive system—play an important role in the body's ability to accept transplanted skin and other organs.

22 Jun 2016

Inflammatory response to mosquito bites can help spread viral infections

Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found.

22 Jun 2016

Food allergies linked to diet and gut microbiome

The development of food allergies in mice can be linked to what their gut bacteria are being fed, reports a study published June 21 in Cell Reports. Rodents that received a diet with average calories, sugar, and fiber content from birth were shown to have more severe peanut allergies than those that received a high-fiber diet.

21 Jun 2016

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation.

21 Jun 2016

Fractional dosing approach could be used to control yellow fever outbreaks during vaccine shortages

The yellow fever vaccine given as one fifth of the regular dose could be used to control an outbreak in case of vaccine shortages.

20 Jun 2016

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear.

20 Jun 2016

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria.

17 Jun 2016

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

When the body is fighting an invading pathogen, white blood cells--including T cells--must respond. Now, Salk Institute researchers have imaged how vital receptors on the surface of T cells bundle together when activated.

16 Jun 2016

New immunotherapy treatment could change the way cancer is treated

In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, a new approach in cancer treatment that has a promising outlook.

16 Jun 2016

Interdisciplinary approach to improve cancer treatments

Whether it focuses on determining why certain cancers develop drug resistance, finding a way to improve individual's immune systems or better understanding cancer cell evolution, fundamental scientific research will "stand up to cancer" with three new awards from the National Science Foundation.

15 Jun 2016

Researchers find unexpected connection between two types of calming immune cells

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells.

15 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

CD36 receptor in nasal sensory neurons may be linked to preference for fatty food

A paper by Brazilian researchers published in the journal Scientific Reports describes a study showing that a subgroup of olfactory neurons in the nasal cavity express a cellular receptor specializing in the transport of lipid molecules.

14 Jun 2016

EPFL researchers reprogram TAMs to prevent tumor metastasis

One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.

14 Jun 2016

Study opens up new strategy to make immunotherapy more effective for different cancer types

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago, working with mice, were able to increase the response rate for these new immunotherapy agents.

14 Jun 2016

Nearly half of newly-infected HIV patients experience neurologic issues

A team led by researchers from UCSF and Yale has found that half of people newly infected with HIV experience neurologic issues. These neurologic findings are generally not severe and usually resolve after participants started anti-retroviral therapy.

14 Jun 2016

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jun 2016

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that when antibodies develop in response to the biological treatment Remicade (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: Inflectra or Remsima).

10 Jun 2016

Dr. Pinchas Tsukerman earns prestigious Kaye Innovation Award for research on cancer immunotherapy

The importance of the body's immune system in protecting against the creation of cancerous tumors has been known for a long time. But despite the existence of a competent immune system, some individuals develop tumors, in part because tumors have ways to evade destructive immunity or induce immune-suppression.

9 Jun 2016

Immune Response News and Research

Olive oil-based emulsion shows promise for mycobacterial treatment of bladder cancer

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Inflammatory response to mosquito bites can help spread viral infections

Food allergies linked to diet and gut microbiome

E-cigarette use modifies gene expression important for upper airway immune defense

Fractional dosing approach could be used to control yellow fever outbreaks during vaccine shortages

TUM researchers uncover molecular mechanism of thalidomide

Legions of immune cells play complex role to destroy Legionella bacteria

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

New immunotherapy treatment could change the way cancer is treated

Interdisciplinary approach to improve cancer treatments

Researchers find unexpected connection between two types of calming immune cells

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

CD36 receptor in nasal sensory neurons may be linked to preference for fatty food

EPFL researchers reprogram TAMs to prevent tumor metastasis

Study opens up new strategy to make immunotherapy more effective for different cancer types

Nearly half of newly-infected HIV patients experience neurologic issues

PET imaging can help identify autoimmune inflammation in MS

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

Dr. Pinchas Tsukerman earns prestigious Kaye Innovation Award for research on cancer immunotherapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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