Immune Response News and Research

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Duke researchers develop new model to study why some HPV infections go away and others progress

For people infected with the human papilloma virus (HPV), the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed.

25 Mar 2015

Discovery opens door to possible new ways to break transmission cycle of schistosomiasis

Researchers at Oregon State University have discovered a group of genes in one species of snail that provide a natural resistance to the flatworm parasite that causes schistosomiasis, and opens the door to possible new drugs or ways to break the transmission cycle of this debilitating disease.

25 Mar 2015

Genetic flaws in bowel cancer may trigger immune response at site of tumours

Scientists have found that genetic changes in bowel tumours are linked to the way the body's immune system responds to the cancer, according to research published today (Monday) in the journal Oncoimmunology.

23 Mar 2015

Study reveals functional heterogeneity of CD4 T cells in immune systems

Utilizing a novel transgenic mouse model, Edward Usherwood, PhD of Dartmouth's Norris Cotton Cancer Center and collaborators found that CD4 T cells divide into two different populations that each has a different job. One type performs antiviral functions, and the other survives life in the host.

23 Mar 2015

New triple combination therapy shows promise in controlling advanced melanoma

Results of a new study by UCLA researchers has found that a groundbreaking new triple combination therapy shows promising signs of more effectively controlling advanced melanoma than previous BRAF + MEK inhibitor or BRAF inhibitor + immunotherapy combos alone, and with increased immune response and fewer side effects.

20 Mar 2015

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Pharmacyclics, Inc. today announced that new pre-clinical and clinical data for ibrutinib (IMBRUVICA) will be highlighted at the 2015 American Association for Cancer Research Annual Meeting to be held April 18 – 22, 2015, in Philadelphia, PA.

19 Mar 2015

IU researchers reveal how Toxoplasma parasites modify brain cells

Rodents infected with a common parasite lose their fear of cats, resulting in easy meals for the felines. Now IU School of Medicine researchers have identified a new way the parasite may modify brain cells, possibly helping explain changes in the behavior of mice -- and humans.

19 Mar 2015

OSU researchers find link between low levels of vitamin D and depression in young women

A new study from Oregon State University suggests there is a relationship between low levels of vitamin D and depression in otherwise healthy young women.

19 Mar 2015

Researchers identify promising new approach to treat pulmonary fibrosis

By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children's Hospital Los Angeles, along with colleagues in Mexico and Canada, have identified a promising new approach for the treatment of pulmonary fibrosis.

18 Mar 2015

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Scientists from the Florida campus of The Scripps Research Institute have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease.

18 Mar 2015

Study reveals novel approach to treat breast cancer

A means of reprogramming a flawed immune response into an efficient anti-tumoral one was brought to light by the results of a translational trial relating to breast cancer. Thanks to the innovative combination of mathematical modelisation and experimentation, only 20 tests were necessary, whereas traditional experimentation would have required 596 tests to obtain the same results.

18 Mar 2015

First clinical trial of new malaria vaccine held in Equatorial Guinea

Equatorial Guinea has held the first clinical trial of a new malaria vaccine known as PfSPZ. Three volunteers participated this month in the trial of the vaccine, which was developed by the American biotechnology company Sanaria. The trial took place at the La Paz Medical Center, the country's premier medical facility, located in Sipopo, just outside the capital.

18 Mar 2015

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

The Ben May Department for Cancer Research at the University of Chicago will hold a day-long symposium on cancer immunotherapy for physicians and researchers.

18 Mar 2015

New drug-like molecule shows promise in preventing MS progression

Walter and Eliza Hall Institute scientists have developed a new drug-like molecule that can halt inflammation and has shown promise in preventing the progression of multiple sclerosis (MS).

17 Mar 2015

Two American scientists receive Paul Ehrlich and Ludwig Darmstaedter Prize

Two American scientists, James P. Allison and Carl H. June, will today receive the Paul Ehrlich and Ludwig Darmstaedter Prize in the Paulskirche in Frankfurt. Both give the patient's own immune system the lasting ability to fight cancer, Allison against late stage melanoma, June against leukemia.

16 Mar 2015

Flu vaccine based upon four strains of inactivated influenza enhances flu protection

A flu vaccine given just under the surface of the skin that includes four strains of inactivated influenza could be more protective than a similar flu vaccine containing only three strains, Saint Louis University research found.

16 Mar 2015

HBV genotype C HBeAg seroconversion rate ‘negligible’

Patients with chronic hepatitis B virus genotype C infection who are positive for hepatitis B e antigen should not delay antiviral treatment in the hope of seroconversion, Korean researchers recommend.

13 Mar 2015

Guanabenz drug prevents myelin loss, alleviates symptoms of MS in animal models

An FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study.

13 Mar 2015

'Turbocharged' protein holds promise in hemophilia gene therapy

Using gene therapy to produce a mutant human protein with unusually high blood-clotting power, scientists have successfully treated dogs with the bleeding disorder hemophilia, without triggering an unwanted immune response.

13 Mar 2015

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that affects approximately 200,000 people a year in the United States and has a higher mortality rate than breast and prostate cancer combined. The condition most often occurs in people who are critically ill or who have significant injuries; those who do survive it often experience profound skeletal muscle weakness.

12 Mar 2015

Immune Response News and Research

Duke researchers develop new model to study why some HPV infections go away and others progress

Discovery opens door to possible new ways to break transmission cycle of schistosomiasis

Genetic flaws in bowel cancer may trigger immune response at site of tumours

Study reveals functional heterogeneity of CD4 T cells in immune systems

New triple combination therapy shows promise in controlling advanced melanoma

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

IU researchers reveal how Toxoplasma parasites modify brain cells

OSU researchers find link between low levels of vitamin D and depression in young women

Researchers identify promising new approach to treat pulmonary fibrosis

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Study reveals novel approach to treat breast cancer

First clinical trial of new malaria vaccine held in Equatorial Guinea

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

New drug-like molecule shows promise in preventing MS progression

Two American scientists receive Paul Ehrlich and Ludwig Darmstaedter Prize

Flu vaccine based upon four strains of inactivated influenza enhances flu protection

HBV genotype C HBeAg seroconversion rate ‘negligible’

Guanabenz drug prevents myelin loss, alleviates symptoms of MS in animal models

'Turbocharged' protein holds promise in hemophilia gene therapy

Early mobility therapy improves outcomes of patients with acute respiratory distress syndrome

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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