Immune Response News and Research

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Study finds important links between Pf malaria and endemic Burkitt Lymphoma

New research, presented this morning at the 54th Annual Meeting of the American Society of Hematology (ASH), has identified important associations between Plasmodium falciparum (Pf) malaria and endemic Burkitt Lymphoma (eBL) that may help researchers identify young children who are more susceptible to eBL.

12 Dec 2012

Study finds high serum galectin-1 levels in Hodgkin lymphoma patients

Blood levels of an immunity-related protein, galectin-1, in patients with newly diagnosed Hodgkin lymphoma reflected the extent of their cancer and correlated with other predictors of outcome, scientists reported at the American Society of Hematology annual meeting.

11 Dec 2012

Severe RSV disease may impair innate immune response in infants

Infants with severe lower respiratory tract infection caused by respiratory syncytial virus (RSV) may have a dysfunctional innate immune response that relates to the severity of their disease.

10 Dec 2012

Immune dysfunction pinpointed in developmental disorder

Children with neurodevelopmental abnormalities resulting from duplication of the methyl-CpG binding protein 2 gene also have impaired T-helper-cell 1 responses, research shows.

10 Dec 2012

Sanofi Pasteur’s IMOJEV vaccine against Japanese encephalitis is now available in Australia

Sanofi Pasteur, the vaccines division of Sanofi, announced today that IMOJEV vaccine against Japanese encephalitis (JE) is now available in Australia.

10 Dec 2012

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

The University of Texas MD Anderson Cancer Center and GlaxoSmithKline (GSK) have signed a research collaboration and license agreement to develop new therapeutic antibodies that promote an immune system attack against cancer.

10 Dec 2012

Scancell announces preliminary results from Part 1 of ImmunoBody vaccine Phase 1/2 MM trial

Scancell Holdings Plc, the developer of therapeutic cancer vaccines, is pleased to announce preliminary results from Part 1 of the Phase 1/2 clinical trial of its DNA ImmunoBody vaccine in patients with Stage III/IV malignant melanoma.

6 Dec 2012

C-reactive protein levels increased in schizophrenia

Patients with schizophrenia have elevated levels of high-sensitivity C-reactive protein compared with mentally healthy individuals, US researchers report.

6 Dec 2012

C-reactive protein levels increased in schizophrenia

Patients with schizophrenia have elevated levels of high sensitivity C-reactive protein compared with mentally healthy individuals, US researchers report.

6 Dec 2012

Rice bran offers promising cancer prevention properties

A recent University of Colorado Cancer Center review in the journal Advances in Nutrition shows that rice bran offers promising cancer prevention properties. Meanwhile, an ongoing clinical trial is testing the effectiveness of rice bran in preventing the recurrence of colon cancer.

6 Dec 2012

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

These results reveal how the immune system can then limit the effectiveness of some cancer chemotherapies. The researchers now intend to block the molecules responsible for negative immune system activation to increase the efficiency of chemotherapy. A clinical trial to test this hypothesis should begin very soon.

5 Dec 2012

New clues about B. burgdorferi could lead to novel strategy to reduce Lyme disease

New clues about the bacteria that cause Lyme disease could lead to a novel strategy to reduce infections, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology, on December 4.

4 Dec 2012

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Researchers in the Nutritional Immunology and Molecular Medicine Laboratory at Virginia Bioinformatics Institute have discovered how a common diarrhea-causing bacterium sends the body's natural defenses into overdrive, actually intensifying illness while fighting infection.

1 Dec 2012

Study of hospital-acquired infection yields potential therapeutic target

30 Nov 2012

VAC-3S immunotherapeutic vaccine for HIV completes first clinical development phase

InnaVirVax, a biopharmaceutical company specialized in research and development on therapeutic and diagnostic solutions for diseases linked to immune dysregulation, has just announced successful completion of the first clinical development phase for VAC-3S immunotherapy in the treatment of HIV infections.

30 Nov 2012

Study shows how anaplasma phagocytophilum subverts natural processes

Bacteria that cause the tick-borne disease anaplasmosis in humans create their own food supply by hijacking a process in host cells that normally should help kill the pathogenic bugs, scientists have found.

30 Nov 2012

SLU study to use various assays for new TB vaccine development

A pilot study at Saint Louis University Center for Vaccine Development could shape the future of tuberculosis vaccine research by developing tests to identify the most promising vaccine candidates to address this global health crisis.

29 Nov 2012

microRNA-223 molecule plays a surprising role in protecting brain cells from stroke effects

A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how cells respond to the temporary loss of blood supply brought on by stroke - and thus the cells' likelihood of suffering permanent damage.

29 Nov 2012

Microneedle-based measles vaccine can immunize against measles

Measles vaccine given with painless and easy-to-administer microneedle patches can immunize against measles at least as well as vaccine given with conventional hypodermic needles, according to research done by the Georgia Institute of Technology and the Centers for Disease Control and Prevention (CDC).

28 Nov 2012

GW professor receives federal grant to study effects of microsporidia in HIV patients

Imtiaz A. Khan, M.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, received a $1.6 million federal grant from the National Institute of Allergy and Infectious Diseases to study the effects of microsporidia-opportunistic inter-cellular pathogens-that cause morbidity and mortality in HIV patients.

27 Nov 2012

Immune Response News and Research

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

Study finds high serum galectin-1 levels in Hodgkin lymphoma patients

Severe RSV disease may impair innate immune response in infants

Immune dysfunction pinpointed in developmental disorder

Sanofi Pasteur’s IMOJEV vaccine against Japanese encephalitis is now available in Australia

GSK, MD Anderson partner to develop new therapeutic antibodies against cancer

Scancell announces preliminary results from Part 1 of ImmunoBody vaccine Phase 1/2 MM trial

C-reactive protein levels increased in schizophrenia

C-reactive protein levels increased in schizophrenia

Rice bran offers promising cancer prevention properties

Combining 5-fluorouracil and IL-1 beta inhibitor can improve effectiveness of chemotherapy

New clues about B. burgdorferi could lead to novel strategy to reduce Lyme disease

Tissue damage, disease severity in C. diff. infection associated with disruption of PPARγ pathway

Study of hospital-acquired infection yields potential therapeutic target

VAC-3S immunotherapeutic vaccine for HIV completes first clinical development phase

Study shows how anaplasma phagocytophilum subverts natural processes

SLU study to use various assays for new TB vaccine development

microRNA-223 molecule plays a surprising role in protecting brain cells from stroke effects

Microneedle-based measles vaccine can immunize against measles

GW professor receives federal grant to study effects of microsporidia in HIV patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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