Immune Response News and Research

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New synthetic lung surfactant could revolutionize treatment for premature babies

Scientists have developed a new lung surfactant that is produced synthetically rather than relying on the use of animal tissues.

25 Mar 2024

New method predicts sepsis and organ failure in children

University of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ failure.

25 Mar 2024

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments.

25 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

UCLA researchers develop promising vaccine against deadly melioidosis bacterium

In a mouse study, UCLA researchers tested a vaccine against the bacterium that causes melioidosis and found it was highly protective against the disease, which is endemic in many tropical areas, causing approximately 165,000 cases with 89,000 fatalities around the world each year.

22 Mar 2024

LungVax vaccine uses DNA technology to prevent lung cancer

Developed by scientists from the University of Oxford, the Francis Crick Institute and University College London, the LungVax vaccine uses technology similar to the highly successful Oxford/AstraZeneca COVID-19 vaccine.

21 Mar 2024

Middle age: A critical turning point for brain health and cognition

Review emphasizes the significance of midlife for cognitive trajectories and brain health, advocating for research models that capture non-linear changes to better understand the unique processes occurring during this period.

20 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

SARS-CoV-2-associated ARDS can damage the heart without direct infection

SARS-CoV-2, the virus that causes COVID-19, can damage the heart even without directly infecting the heart tissue, a National Institutes of Health-supported study has found.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

19 Mar 2024

Exposure to high heat may increase inflammation and interfere with immune system functions

Short-term exposure to higher heat may increase inflammation and interfere with normal immune system functions in the body, which may, in turn, increase susceptibility to infections and accelerate the progression of cardiovascular disease, according to preliminary research to be presented at the American Heart Association's Epidemiology and Prevention│Lifestyle and Cardiometabolic Scientific Sessions 2024, March 18- 21, in Chicago.

19 Mar 2024

New drug candidates show promise to reverse HIV immune evasion

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

19 Mar 2024

Discovering the on-switch for rare genetic inflammatory diseases

University of Queensland researchers have discovered how the 'on-switch' for the body's inflammation machinery can get stuck and cause rare genetic inflammatory diseases.

18 Mar 2024

CHOP study uncovers metabolic key to faster immune response

Researchers from Children's Hospital of Philadelphia identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.

15 Mar 2024

Eating fatty food before surgery may affect memory-related cognitive function in older adults

Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults – and, new research in animals suggests, even in young adults.

15 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Living with IBD: What coping strategies are most effective?

The results of a systematic review that explored the impact of different coping strategies for people living with inflammatory bowel disease (IBD).

14 Mar 2024

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Globally, more than half of patients die after infection with the neglected tropical disease, melioidosis, often before they are diagnosed.

13 Mar 2024

Research uncovers mechanical explanation for instability in the lungs of ARDS patients

Researchers at the University of Minnesota Twin Cities may have discovered a mechanical explanation for instability observed in the lungs in cases of acute respiratory distress syndrome (ARDS), particularly in the aftermath of respiratory illnesses such as COVID-19 or pneumonia.

12 Mar 2024

Immune Response News and Research

New synthetic lung surfactant could revolutionize treatment for premature babies

New method predicts sepsis and organ failure in children

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

UCLA researchers develop promising vaccine against deadly melioidosis bacterium

LungVax vaccine uses DNA technology to prevent lung cancer

Middle age: A critical turning point for brain health and cognition

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

SARS-CoV-2-associated ARDS can damage the heart without direct infection

Immune cell protein identified as potential target for rare liver cancer treatment

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Exposure to high heat may increase inflammation and interfere with immune system functions

New drug candidates show promise to reverse HIV immune evasion

Discovering the on-switch for rare genetic inflammatory diseases

CHOP study uncovers metabolic key to faster immune response

Eating fatty food before surgery may affect memory-related cognitive function in older adults

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Living with IBD: What coping strategies are most effective?

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Research uncovers mechanical explanation for instability in the lungs of ARDS patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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