Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

40-year timeline of HIV: Testing assays, global burden, prevalence, treatment, and challenges

Announcing a new article publication for Zoonoses journal. More than 77 million individuals have been infected with the human immunodeficiency virus (HIV) and approximately 37.6 million people are living with HIV infection.

4 Jan 2024

Factors that increase the risk of severe COVID-19 in children

Study analyzes a nationwide cohort of hospitalized children and adolescents in Germany, identifying key risk factors for severe SARS-CoV-2 infection, including obesity, Trisomy 21, and neurological conditions.

3 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

UKHSA announces concerning rise in antibiotic-resistant Shigella cases

There has been a concerning rise in cases of extensively antibiotic-resistant Shigella sonnei infections, mainly in gay, bisexual, and other men who have sex with men (GBMSM), UKHSA has announced.

21 Dec 2023

Digital algorithm ePOCT+ successfully reduces antibiotic prescriptions in children, combating antimicrobial resistance

Study demonstrates how the ePOCT+ digital algorithm effectively guides healthcare providers in prescribing antibiotics for children, significantly reducing unnecessary antibiotic use and addressing antimicrobial resistance without compromising patient outcomes.

18 Dec 2023

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

B cell deficiency is a common condition that can result either from immunosuppressant drugs used to treat autoimmune disease or certain cancers -; such as rituximab (RTX) -; or from natural immune deficiency.

18 Dec 2023

Optimizing cervical cancer screening: New study evaluates best approaches for HIV-positive women

Researchers evaluated the effectiveness and outcomes of various cervical cancer screening strategies for women living with HIV in Tanzania, supporting World Health Organisation's (WHO's) 2021 guidelines for reducing cervical cancer mortality in this high-risk group.

14 Dec 2023

Global study reveals link between psychological distress and unhealthy eating in adolescents

Study in Scientific Reports analyzed data from 222,401 adolescents across 61 countries, finding a significant correlation between psychological distress and unhealthy eating habits, with notable differences across sexes and regions.

13 Dec 2023

How does the combined effect of smoking and HIV infection influence the aging-related manifestations?

The combination of human immunodeficiency virus (HIV) infection and smoking influence.

12 Dec 2023

The influence of vitamin supplementation on longitudinal patterns of maternal vitamin status from preconception to post-delivery

Researchers secondary analyzed the NiPPeR randomized clinical trial (RCT) data to assess maternal vitamin levels pre-conception, during pregnancy, and post-delivery and also explored the impact of vitamin supplementation before and during gestation.

11 Dec 2023

The association between viral infections and glioma risk

The causal relationship between viral infection and glioma.

7 Dec 2023

Major UK study finds high demand and efficacy for HIV PrEP among sexual health service attendees

HIV PrEP requirement, duration, uptake, and usage among sexual health services (SHS) attendees in England.

4 Dec 2023

Study highlights importance of HIV prevention for migrants in EU/EEA

Across the 30 countries of the European Union and European Economic Area (EU/EEA), 22,995 new HIV diagnoses were reported in 2022.

30 Nov 2023

Herpes zoster vaccination and healthy aging: Study connect the dots

Vaccination with recombinant zoster vaccine (RZV) prevents Herpes Zoster (HZ) infection.

30 Nov 2023

Study estimates hepatitis C infection seroprevalence in pregnant women

Researchers estimate the seroprevalence of hepatitis C virus in pregnant women globally and in World Health Organization-specific regions.

22 Nov 2023

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

The impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4+ (CD4+ ) Thymus cells (T cells) viz.

21 Nov 2023

Breakthrough in tuberculosis treatment: TB-PRACTECAL trial reveals efficacy of new oral regimen

The TB-PRACTECAL clinical trial outcomes, which evaluated the efficacy and safety of oral bedaquiline.

20 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

Study sheds light on specific variants responsible for rare and serious disorder

Many disorders are caused by genetic variants; to make matters worse, the genetic origin of most disorders remains unknown.

15 Nov 2023