Immunoglobulin News and Research

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First study to demonstrate IVIg effective longer than a year

A purified mixture of human antibodies called intravenous immunoglobulin (IVIg) provides lasting benefits to patients with Alzheimer's disease (AD), according to researchers at the NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

25 Jul 2006

Antibodies show promise in treating Alzheimer's

Researchers say infusing human antibodies into people with Alzheimer's disease appears to help stop the disease from getting worse and may even help the patients improve.

19 Jul 2006

Researchers identify gene used to recognize pathogens

Researchers at the Johns Hopkins Bloomberg School of Public Health have identified a gene in the Anopheles gambiae mosquito's DNA that is central to the insect's ability to defend against infectious pathogens, including Plasmodium, the parasite that causes malaria in humans.

27 Jun 2006

Researchers identify gene used to recognize pathogens

Researchers have identified a gene in the Anopheles gambiae mosquito's DNA that is central to the insect's ability to defend against infectious pathogens, including Plasmodium, the parasite that causes malaria in humans.

20 Jun 2006

Costly IVIg could be replaced with synthetic blood product

Patients suffering from a life-threatening bleeding disorder are closer to having access to a more effective treatment.

1 Jun 2006

Gene family of potential tumor inhibitors identified

Proteins from a newly discovered family of genes, LRIG, function as a retardant for a protein that is important to tumor cells. It is probably this mechanism that lends the gene family its inhibiting effect on cancer tumors.

17 May 2006

HIV reveals another secret to its success

In HIV infection, a protein produced by infected cells penetrates immune B cells, preventing them from producing antibodies that could do the virus real harm.

20 Mar 2006

Researchers find a way to make plants produce more antigens needed for vaccines

Scientists have developed a new kind of molecule which they believe could ultimately lead to the development of a vaccine against HIV using genetically modified tobacco.

13 Mar 2006

Discovery of mechanisms responsible for the difference in immune response between male and female mice

The differences in the male and female immune responses, which make females more prone to autoimmune disease and males more subject to infections, are established during puberty.

23 Feb 2006

Approval of first immune globulin for use beneath the skin

The U.S. Food and Drug Administration (FDA) has announced the approval of the first immune globulin product for subcutaneous injection for the prevention of serious infections in patients with Primary Immune Deficiency Diseases (PIDD).

10 Jan 2006

Children could be saved from neuroblastoma using antibody therapy

Combination of T cell, antibody to neuroblastoma cells and molecule that spurs T cell growth is designed to treat low initial tumor levels or small cancer cell populations that survive initial treatment, according to St. Jude.

22 Dec 2005

New anthrax antibody

A new anthrax antibody engineered by scientists at The University of Texas at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more expensive antibodies.

2 Dec 2005

Possible viral cause of Kawasaki disease identified

In an important discovery in infectious disease research, a team of scientists from Northwestern University has identified a possible viral cause of Kawasaki disease, the most common cause of acquired heart disease in children in developed nations.

20 Nov 2005

Xolair (omalizumab) brings new hope for severe asthma sufferers

The launch of a new drug to treat asthma has given new hope to people with severe asthma.

8 Nov 2005

Ginseng shown to significantly offer protection from colds

According to new research people who take ginseng suffer from far fewer colds.

25 Oct 2005

Steroids significantly reduce heart damage in children with Kawasaki's disease

When added to standard treatment, steroids significantly reduce the odds of developing heart damage in children with Kawasaki's disease, according to a study in the October issue of Pediatrics. These findings address a gap in knowledge.

3 Oct 2005

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

In a paper appearing online in advance of print publication of the October 1 issue of the Journal of Clinical Investigation, Adam Boruchov and colleagues from Memorial Sloan Kettering Cancer Center dissect the contributions of CD32 isoforms in human dendritic cell (DC) activation and function.

26 Sep 2005

Scintigraphy scan may help clinicians properly diagnose and then treat two forms of cardiac amyloidosis

"Clinically, this finding helps differential diagnosis and reduces the risk of misdiagnosis between two conditions with very different therapeutic options," said Claudio Rapezzi, M.D. from the University of Bologna and S. Orsola-Malpighi Hospital in Bologna, Italy.

21 Sep 2005

Infusion nurses examine need for standards of practice in immunoglobulin therapy

A review article published in the July/August 2005 Journal of Infusion Nursing examines the need for established treatment guidelines to support doctors and nurses in correctly dosing and administering intravenous immunoglobulin (IVIG) as replacement therapy in patients with primary immunodeficiency (PI) disorders, who do not produce adequate levels of antibodies essential in fighting infectious diseases.

13 Aug 2005

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

A Mayo Clinic study demonstrates that only those multiple sclerosis (MS) patients with evidence for antibody deposition or complement activation -- immune cells that can cause tissue destruction -- in their lesions are likely to respond to plasma exchange, a treatment for acute MS attacks.

11 Aug 2005