Immunosuppression News and Research

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Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Angiotensin receptor blockers could improve response to cancer immunotherapy

A research team led by investigators at Massachusetts General Hospital and the Massachusetts Institute of Technology has found that combining a specialized version of an antihypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies.

30 Apr 2019

New chemical synthesis strategy leads to identification of novel, simpler derivatives

A new chemical synthesis strategy to harvest the rich information found in natural products -- organic compounds isolated from natural sources -- has led to the identification of novel, simpler derivatives with potential to selectively protect neurons, important for neurodegenerative diseases like Alzheimer's disease, or to prevent the immune system from rejecting organ transplants, according to a Baylor University-led study.

25 Apr 2019

Air pollution increases risk for respiratory hospitalization among childhood cancer survivors

Poor air quality days significantly increase the risk of hospitalizations for respiratory issues in young survivors of cancer, according to a study conducted by researchers at Huntsman Cancer Institute at the University of Utah and published in the International Journal of Environmental Research and Public Health.

24 Apr 2019

Researchers explore biological mechanisms behind obesity-cancer link

New studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers explore biological mechanisms behind obesity and its link with cancer.

1 Apr 2019

FDA approves new drug to treat adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Mayzent (siponimod) tablets to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.

27 Mar 2019

Combined immunosuppression may be effective, safe in treating older patients with Crohn’s disease

Combining medications that suppress the immune system has been successful in treating young patients with Crohn's disease, but some physicians have been reluctant to use this strategy in older patients because of concerns about safety.

20 Mar 2019

Cell therapy may be alternative strategy for treatment of chronic kidney disease

Wake Forest Institute for Regenerative Medicine scientists are working on a promising approach for treatment of chronic kidney disease - regeneration of damaged tissues using therapeutic cells.

15 Mar 2019

Tiny implantable 'tea bag' senses glucose levels and automatically releases insulin

Children with Type 1 diabetes have only one option to control their blood sugar: insulin treatment. Ravaged by an autoimmune disease that attacks their own pancreas and islets -- microscopic clusters of cells that sense blood sugar and produce insulin -- patients are forced to rely on insulin from an external source.

11 Mar 2019

New screening method could catch organ rejection much earlier without a biopsy needle

Too often, it's only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and a urine test could catch rejection much earlier, more comprehensively, and without a biopsy needle.

20 Feb 2019

A new approach towards future treatment of diabetes

It is said that the eyes are the window to the soul, but they may also open the door for discovering new ways to achieve immune tolerance to transplanted islets in type 1 diabetes, according to research from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine.

3 Feb 2019

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer.

29 Jan 2019

New resource-based approach to improve HIV care in low- and middle-income countries

A practical resource-based public health approach for the rapid initiation of antiretroviral therapy in HIV-infected individuals living in low- and middle-income countries could save thousands of lives, according to an Essay published January 15 in the open-access journal PLOS Medicine by Mark Tenforde of the University of Washington School of Medicine, and colleagues.

18 Jan 2019

Immunosuppression News and Research

Further Reading

Angiotensin receptor blockers could improve response to cancer immunotherapy

New chemical synthesis strategy leads to identification of novel, simpler derivatives

Air pollution increases risk for respiratory hospitalization among childhood cancer survivors

Researchers explore biological mechanisms behind obesity-cancer link

FDA approves new drug to treat adults with relapsing forms of MS

Combined immunosuppression may be effective, safe in treating older patients with Crohn’s disease

Cell therapy may be alternative strategy for treatment of chronic kidney disease

Tiny implantable 'tea bag' senses glucose levels and automatically releases insulin

New screening method could catch organ rejection much earlier without a biopsy needle

A new approach towards future treatment of diabetes

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

New resource-based approach to improve HIV care in low- and middle-income countries

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

Researchers reveal how key transcription factor keeps the immune system in check

Scientists discover cellular mechanism that triggers pneumonia in humans

The Lancet study: First baby born following uterus transplantation from deceased donor

Study points toward new strategies for managing organ transplantation

New method could improve outcome of leukemia patients receiving stem-cell transplants

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

New method to block immunosuppression in cancer discovered

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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