In Vitro Fertilization (IVF) News and Research

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Researchers investigate predictors for adverse outcome in IVF singletons

In Sweden almost 40 000 children have now been born after IVF, around 3 500 each year, and IVF children constitute 3% of all newborns. "This represents a large number of children and any adverse outcomes related to IVF are therefore a major public health issue," said Dr. Antonina Sazonova, from Sahlgrenska University Hospital, Gothenburg, Sweden, who carried out the research with colleagues from the hospital and from Lund University.

6 Jul 2011

Cleavage stage embryo with aneuploidy can undergo genetic normalisation process

Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo with an incorrect number of chromosomes was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes.

5 Jul 2011

Hope for fertility spreads through postcards

The campaign sends a multiplied message of hope for fertility in form of postcards with stories, including the key message on prevention and treatment. Thousands of postcards with moving stories are expected to cross Europe until October 2011.

4 Jul 2011

Research addresses chromosomal imbalance in embryos

Joint research between the University of Kent's Professor Darren Griffin, London Bridge Fertility Centre and BlueGnome Ltd has addressed chromosomal imbalance in embryos, a condition that is currently the major cause of pregnancy loss in IVF.

4 Jul 2011

Study shows effect of maternal height on multiple implantation

The researchers say that this is the first time the effect of maternal height on multiple implantation has been shown.

4 Jul 2011

Primiparity, maternal smoking and BMI linked to risk of pre-term birth

4 Jul 2011

New model may help reduce multiple pregnancies in women

Dr Jan Holte told the annual meeting of the European Society for Human Reproduction and Embryology, that if this model were to be applied in all fertility clinics, it had the potential to reduce the twin rates to the level of just under two percent seen in the normal population. Already, another four clinics have started to use the model.

4 Jul 2011

New insight into oocyte chromosome abnormalities

Ovarian stimulation undertaken by women of advanced maternal age receiving fertility treatment may be disrupting the normal pattern of meiosis - a critical process of chromosome duplication followed by two specialised cell divisions in the production of oocytes and sperm - and leading to abnormalities of chromosome copy numbers that result in IVF failure, pregnancy loss or, more rarely, the birth of affected children with conditions such as Down's syndrome, which is caused by the inheritance of three copies of chromosome 21.

4 Jul 2011

Small 'antifreeze' molecules more effective in protecting proteins than larger ones

Scientists have made an important step forward in their understanding of cryoprotectants - compounds that act as natural 'antifreeze' to protect drugs, food and tissues stored at sub-zero temperatures.

24 Jun 2011

Antimullerian hormone test can help indicate number of eggs, pregnancy in women

Given how much patients invest in in vitro fertilization (IVF), both financially and emotionally, tools to inform couples about what they might expect during their treatment can be welcome. A study by researchers at Brown University and Women & Infants Hospital shows that as the IVF cycle is beginning, a blood test for levels of a hormone called AMH, or antimullerian hormone, can help predict the number of eggs that will be harvested.

10 Jun 2011

Anti-Mullerian hormone test can indicate reproductive function in young women with cancer

A test that shows how many eggs a woman has in her ovaries may help young women with breast cancer know what their reproductive function will be after chemotherapy, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

NHS directive to fertility clinics

NHS fertility clinics will be ordered to meet their responsibilities and provide adequate levels of IVF treatment, amid growing concerns. There are claims that a “postcode lottery” is reducing couples' chances of having a baby.

5 Jun 2011

Pacific Reproductive Center celebrates Annual Baby Reunion in Torrance

When April Gooding was born 19 years ago in Torrance, infants like her were called "test tube babies" and in vitro fertilization was still considered experimental. Nearly two decades later, almost 4 million IVF babies have been born, including several hundred who will join April and the fertility expert who helped create her as one of his first successes.

1 Jun 2011

Researchers devise new genetic technique for IVF embryos

Researchers at the Johns Hopkins University School of Medicine have devised a new technique, which helps couples that are affected by or are carriers of genetic diseases have in vitro fertilized babies free of both the disease in question and other chromosomal abnormalities. The results were reported in the April issue of Fertility and Sterility.

24 May 2011

New genetic testing technology for IVG embryos

23 May 2011

New Seattle IVF program cuts expense of women conceiving child with donated egg

A new, first-of-its-kind Seattle in vitro fertilization program can save women 30 percent on the expense of conceiving a child with a donated egg. The cost-savings comes through Seattle Reproductive Medicine's new shared-donor program that lets two women use eggs provided by a single donor.

21 May 2011

Gene variant linked to infertility in women

A variation in a gene involved in regulating cholesterol in the bloodstream also appears to affect progesterone production in women, making it a likely culprit in a substantial number of cases of their infertility, a new study from Johns Hopkins researchers suggests.

16 May 2011

IVF causing multiple birth rates fall

Birth rates for IVF twins and triplets have begun to fall in line with government targets aimed at reducing health risks caused by multiple pregnancies. This fall shows the efficacy of the guidelines brought in by the Human Fertilization and Embryology Authority (HFEA) that urged UK fertility clinics to limit multiple births to no more than 24% in 2009/10. Among naturally-conceived babies, only around one in 70 is a twin.

15 May 2011

Study finds strong link between live birth rates and number of eggs retrieved in one IVF cycle

An analysis of over 400,000 IVF cycles in the UK has shown that doctors should aim to retrieve around 15 eggs from a woman's ovaries in a single cycle in order to have the best chance of achieving a live birth after assisted reproduction technology.

11 May 2011

Psychological distress affects IVF outcomes

There is no doubt that undergoing infertility treatment is stressful, with high rates of anxiety and depression reported by many patients. Mind/body therapies designed to help women reduce stress earlier in the treatment process result in higher pregnancy rates, but little is known specifically about the impact of these therapies on women undergoing in vitro fertilization (IVF).

10 May 2011