Indomethacin News and Research

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FDA approves APP Pharmaceuticals' Indomethacin for Injection

APP Pharmaceuticals, Inc., a wholly owned subsidiary of Fresenius Kabi Pharmaceuticals Holding, Inc., announced today that it has received approval from the U.S. Food and Drug Administration (FDA) to market Indomethacin for Injection. Indomethacin is therapeutically equivalent to the reference-listed drug INDOCIN® I.V., by Lundbeck, Inc.

23 Mar 2010

Bedford Laboratories launches Indomethacin for Injection

Bedford Laboratories™, a division of Ben Venue Laboratories, Inc., a provider of select specialty injectables, is pleased to announce the addition of Indomethacin for Injection to its existing product line. This product is AP rated and is equivalent to Indocin® by Lundbeck, Inc. Indomethacin for Injection is indicated to close a hemodynamically significant patent ductus arteriosus in premature infants weighing between 500 and 1750 g when after 48 hours usual medical management (e.g., fluid restriction, diuretics, digitalis, respiratory support, etc.) is ineffective.

17 Feb 2010

Study: EP4 agonist may reduce gastric bleeding and inflammation

Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding.

19 Nov 2009

Experimental study shows beneficial effects of Vardenafil on NSAID-induced gastric ulcer

Indomethacin has been proved by epidemiological and experimental studies to be closely associated with peptic ulcer development. Vardenafil is a potent phosphodiesterase 5 inhibitor and its effects on the gastric mucosa havenot been reported.

19 Nov 2009

Studies provide clues to how Alzheimer’s disease develops and may be treated

The anti-inflammatory drug indomethacin could hold promise as a treatment for Alzheimer's disease, says a Saint Louis University doctor and researcher.

12 Jul 2009

Salad herb shows potential gastric anti-ulcer activity

Gastric ulcer is an illness that affects a considerable number of people worldwide. Although the introduction of proton-pump inhibitors to the classic anti-ulcer therapy has revolutionized treatment of peptic ulcers and other gastrointestinal disorders, there is still no complete cure for this disease.

7 May 2009

Ibuprofen linked to lower risk of Alzheimer's

Long-term use of ibuprofen and other drugs commonly used for aches and pains was associated with a lower risk of Alzheimer's disease, according to a study published in the May 6, 2008, issue of Neurology, the medical journal of the American Academy of Neurology. Previous studies have shown conflicting results, but this is the longest study of its kind.

5 May 2008

Indomethacin a common drug for stopping preterm labor may be harmful for babies

A drug commonly used to halt premature labor may be associated with brain damage and intestinal issues in premature babies, according to a new analysis of studies on the issue publishedthis monthin American Journal of Obstetrics and Gynecology.

21 Nov 2007

Indomethacin drug for stopping preterm labor may be harmful for babies

A drug commonly used to halt premature labor may be associated with brain damage and intestinal issues in premature babies, according to a new analysis of studies on the issue published today in American Journal of Obstetrics and Gynecology.

2 Nov 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Celecoxib offers promise for premature babies

Scientists have found evidence that the cox-2 inhibitor celecoxib, a common pain reliever used to treat arthritis, may offer a new way to reduce the risk of the most common cause of brain damage in babies born prematurely.

18 May 2007

Lifestyle decisions that may stave off onset of cancer

Personal choices, such as smoking and consumption of fatty foods, have long been linked to increased cancer risk. During recent years, scientists have been seeking to isolate a variety of lifestyle decisions that may stave off the onset of cancer or even reduce tumor formation in their early stages.

14 Nov 2006

Doctors warned that commonly used painkillers linked to increased risk of heart attacks

Doctors in the UK are being warned that commonly used painkillers such as ibuprofen can increase the risk of heart attacks if taken over long periods.

25 Oct 2006

AUA podium session on stone disease

2-phase randomized crossover study on a constant diet with calcium carbonate supplementation at 250 mg 4 times daily.

13 Jun 2006

Common painkillers could up chance of heart failure in seniors

New research has revealed that commonly used over-the-counter painkillers, such as ibuprofen, are linked with a 30% increased risk of first hospital admission for heart failure.

22 May 2006

Economic benefit of federally finded clinical trials exceeds $15 billion

A comprehensive review of all phase III clinical trials supported by one Federal agency finds that, estimated conservatively, the economic benefit in the United States from just eight of these trials exceeded $15 billion over the course of 10 years. The study also found that new discoveries from the trials were responsible for an estimated additional 470,000 healthy years of life. The clinical trials were sponsored by the National Institutes of Health's National Institute of Neurological Disorders and Stroke (NINDS).

28 Apr 2006

Economic benefit of federally finded clinical trials exceeds $15 billion

28 Apr 2006

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

An analysis of 20 years of data on the health of over 900 adults has found that long-term use of traditional nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, cuts the risk for oral cancer in smokers by half.

9 Oct 2005

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Indomethacin News and Research

FDA approves APP Pharmaceuticals' Indomethacin for Injection

Bedford Laboratories launches Indomethacin for Injection

Study: EP4 agonist may reduce gastric bleeding and inflammation

Experimental study shows beneficial effects of Vardenafil on NSAID-induced gastric ulcer

Studies provide clues to how Alzheimer’s disease develops and may be treated

Salad herb shows potential gastric anti-ulcer activity

Ibuprofen linked to lower risk of Alzheimer's

Indomethacin a common drug for stopping preterm labor may be harmful for babies

Indomethacin drug for stopping preterm labor may be harmful for babies

The future of Alzheimer's disease research

Celecoxib offers promise for premature babies

Lifestyle decisions that may stave off onset of cancer

Doctors warned that commonly used painkillers linked to increased risk of heart attacks

AUA podium session on stone disease

Common painkillers could up chance of heart failure in seniors

Economic benefit of federally finded clinical trials exceeds $15 billion

Economic benefit of federally finded clinical trials exceeds $15 billion

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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