Induced Pluripotent Stem Cells News and Research

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Researchers find better way to purify liver cells made from induced pluripotent stem cells

A research team including developmental biologist Stephen A. Duncan, D. Phil., SmartState Chair of Regenerative Medicine at the Medical University of South Carolina, has found a better way to purify liver cells made from induced pluripotent stem cells (iPSCs).

30 Aug 2016

Skin cells derived from autistic donors grow faster than those from control subjects

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, chair of the department of genetics and genome sciences at Case Western Reserve University School of Medicine.

28 Aug 2016

Salk researchers develop new method to create unlimited numbers of precursor kidney cells

Salk Institute scientists have discovered the holy grail of endless youthfulness--at least when it comes to one type of human kidney precursor cell.

25 Aug 2016

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure.

18 Aug 2016

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Researchers have used CRISPR -- a revolutionary new genetic engineering technique -- to convert cells isolated from mouse connective tissue directly into neuronal cells.

11 Aug 2016

New model of Williams syndrome may shed light on neurobiology of the human social brain

In a study spanning molecular genetics, stem cells and the sciences of both brain and behavior, researchers at University of California San Diego, with colleagues at the Salk Institute for Biological Studies and elsewhere, have created a neurodevelopmental model of a rare genetic disorder that may provide new insights into the underlying neurobiology of the human social brain.

11 Aug 2016

Researchers reprogram skin cells from diabetic foot ulcers to generate iPSCs

The potential to use a patient's own cells to treat non-healing chronic wounds - a serious complication of diabetes - took an important step forward as researchers successfully reprogrammed skin cells taken from diabetic foot ulcers to form induced pluripotent stem cells (iPSCs).

10 Aug 2016

Sharing of patients' stem cells could boost bipolar disorder research

Stem cells from patients with bipolar disorder are being made available to scientists around the world to boost research into the condition.

9 Aug 2016

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors -- even as it changed the lives of the babies born with it during the pre-Zika era.

8 Aug 2016

Mice study shows stem cell infusion could help treat glaucoma

An infusion of stem cells could help restore proper drainage for fluid-clogged eyes at risk for glaucoma. That's the upshot of a study led by a Veterans Affairs and University of Iowa team.

26 Jul 2016

Scientists receive $2.4 million grant to advance stem cell therapy for Parkinson's disease

Scientists at The Scripps Research Institute and Scripps Clinic have received a grant of nearly $2.4 million from the California Institute for Regenerative Medicine to support safety and quality tests of a potential stem cell therapy for Parkinson's disease.

22 Jul 2016

Salk scientists propose new molecular criteria for generating naïve stem cells

Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory-generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.

17 Jul 2016

Researches create mini-brain model of idiopathic ASD characterized by early neuronal overgrowth

The vast majority of cases of autism spectrum disorder (ASD) are idiopathic - the cause is unknown.

14 Jul 2016

Scientists use stem cell techniques to unravel biology of autism

The brains of some people with autism spectrum disorder grow faster than usual early on in life, often before diagnosis.

8 Jul 2016

Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the University Clinic of Düsseldorf have established an in vitro model system for investigating nonalcoholic fatty liver disease (NAFLD).

30 Jun 2016

Researchers uncover new clues about role of glucosamine in early embryonic development

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, the babies are exposed to higher levels of glucose in maternal blood.

23 Jun 2016

Understanding cancer resistance in mole-rats may help advance human treatment in future

Naked mole-rats (NMR) are the longest-living rodent species and exhibit 'extraordinary' resistance to cancer. Mole-rats live up to 30 years, 10 times longer than mice, and captured colonies almost never show any type of cancer.

17 Jun 2016

New technique may help replace brain cells, restore memory

Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function.

15 Jun 2016

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth.

13 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016