Induced Pluripotent Stem Cells News and Research

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New stem cell lines help study genetic, biological underpinnings of bipolar disorder

New stem cell lines developed from the skin of adults living with bipolar disorder are providing researchers at the University of Michigan Health System an unprecedented opportunity to delve into the genetic and biological underpinnings of the devastating mood disorder.

24 Aug 2011

IRSF announces new Rett syndrome translational research awards

The International Rett Syndrome Foundation (IRSF) announced today that it is awarding over $650,000 to support eight cutting-edge projects that aim to accelerate translational research to develop treatments for Rett syndrome.

19 Aug 2011

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue.

18 Aug 2011

Scientists reveal why human heart has little regenerative capacity

Stem cell researchers at UCLA have uncovered for the first time why adult human cardiac myocytes have lost their ability to proliferate, perhaps explaining why the human heart has little regenerative capacity.

10 Aug 2011

New genetic cause of retinitis pigmentosa

Combining the expertise of several different labs, University of Iowa researchers have found a new genetic cause of the blinding eye disease retinitis pigmentosa (RP) and, in the process, discovered an entirely new version of the message that codes for the affected protein.

10 Aug 2011

Roadmap to overcome obstacles for using induced pluripotent stem cells

The possibility of developing stem cells from a patient's own skin and using them to treat conditions as diverse as Parkinson's disease, Alzheimer's disease and cancer has generated tremendous excitement in the stem cell research community in recent years. Such therapies would avoid the controversial need for using stem cells derived from human embryos, and in theory, also bypass immunological problems inherent in using cells from one person to treat another.

5 Aug 2011

Mitochondrial genome undergoes random reorganisation during reprogramming

Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would appear that their use is not entirely without risk: during the reprogramming of body cells into iPS cells, disease-causing mutations can creep into the genetic material.

28 Jul 2011

Reprogrammed kidney cells could make transplants and dialysis things of the past

Approximately 60 million people across the globe have chronic kidney disease (CKD), and many will need dialysis or a transplant. Breakthrough research published in the Journal of the American Society Nephrology indicates that patients' own kidney cells can be gathered and reprogrammed.

28 Jul 2011

New strategy for improving development of induced pluripotent stem cells

University of Minnesota Medical School researchers have developed a new strategy to improve the development of induced pluripotent stem cells.

21 Jul 2011

Study overturns long-accepted theories about fundamental aspect of tissue regeneration

Scientists have been wrong for 250 years about a fundamental aspect of tissue regeneration, according to a University of Dayton biologist who says his recent discovery is good news for humans.

14 Jul 2011

Researchers capitalize on 'memories' of adult-derived stem cells for treatment of diabetes

Stem cells from early embryos can be coaxed into becoming a diverse array of specialized cells to revive and repair different areas of the body. Therapies based on these stem cells have long been contemplated for the treatment of diabetes, but have been held back by medical and ethical drawbacks.

14 Jul 2011

STSI receives NIH grant to conduct heart-based research

Researchers looking to find a root cause for heart attacks and coronary artery disease will soon begin using a novel investigative approach that borders on science fiction as they work toward the holy grail of American medicine: preventing the nation's No. 1 killer.

2 Jul 2011

Reduced levels of VAPB protein may play central role in causing ALS

An international team of scientists led by researchers at the University of California, San Diego School of Medicine have used induced pluripotent stem cells (iPSCs) derived from patients with amyotrophic lateral sclerosis (ALS) to reveal for the first time how reduced levels of a specific protein may play a central role in causing at least one inherited form of the disease.

22 Jun 2011

ISCO discovers novel technology to produce pure hepatocyte population

International Stem Cell Corporation announces the discovery of a novel, patent-pending technology to produce unlimited numbers of liver cells (hepatocytes) that are free of contamination with potentially dangerous undifferentiated cells.

16 Jun 2011

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

UCSF's Robert Blelloch, MD, PhD, has received the 2011 Outstanding Young Investigator Award from the International Society for Stem Cell Research, for his pioneering research on the role of molecular tools known as microRNAs in embryonic stem cells and cancer.

16 Jun 2011

Life Technologies introduces CytoTune-iPS Reprogramming Kit

Life Technologies Corporation today announced the launch of CytoTune-iPS Reprogramming Kit -- research technology that provides far improved efficiency over standard methods to develop induced pluripotent stem cells from human somatic cells.

16 Jun 2011

Human adult and embryonic stem cell research can benefit medical science, researchers say

New research says studying both adult and embryonic stem cells can benefit medical science, but banning the study of either type could harm studies of the other.

13 Jun 2011

Legislation that slows human embryonic stem cell research will also harm iPS cells study

Any legislation that slows human embryonic stem cell research is likely to also seriously harm the study of induced pluripotent stem cells, according to a new study by researchers at the Stanford University School of Medicine, the Mayo Clinic and the University of Michigan.

10 Jun 2011

GeneTex to introduce new Easy-iPSC minicircle DNA vector technology in June

GeneTex, a leading manufacturer of antibodies for research use, is pleased to announce they will be launching several new exciting products in June, including the new Easy-iPSC minicircle DNA vector technology.

9 Jun 2011

UAB acquires first cell-processing workstation from SANYO

The University of Alabama at Birmingham has taken a significant step toward making sophisticated cell therapy a part of patient care with its acquisition of the first cell-processing workstation (CPWS) from SANYO North America Corporation (SANYO) in the United States.

9 Jun 2011

Induced Pluripotent Stem Cells News and Research

New stem cell lines help study genetic, biological underpinnings of bipolar disorder

IRSF announces new Rett syndrome translational research awards

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Scientists reveal why human heart has little regenerative capacity

New genetic cause of retinitis pigmentosa

Roadmap to overcome obstacles for using induced pluripotent stem cells

Mitochondrial genome undergoes random reorganisation during reprogramming

Reprogrammed kidney cells could make transplants and dialysis things of the past

New strategy for improving development of induced pluripotent stem cells

Study overturns long-accepted theories about fundamental aspect of tissue regeneration

Researchers capitalize on 'memories' of adult-derived stem cells for treatment of diabetes

STSI receives NIH grant to conduct heart-based research

Reduced levels of VAPB protein may play central role in causing ALS

ISCO discovers novel technology to produce pure hepatocyte population

ISSCR honors UCSF cancer scientist with 2011 Outstanding Young Investigator Award

Life Technologies introduces CytoTune-iPS Reprogramming Kit

Human adult and embryonic stem cell research can benefit medical science, researchers say

Legislation that slows human embryonic stem cell research will also harm iPS cells study

GeneTex to introduce new Easy-iPSC minicircle DNA vector technology in June

UAB acquires first cell-processing workstation from SANYO

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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