Infectious Diseases News and Research

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Partial success reported in the Phase 3 trial of HIV/AIDS vaccine

GeoVax Labs, Inc., an Atlanta-based, biopharmaceutical company developing human vaccines for HIV/AIDS (HIV-1, Human Immunodeficiency Virus), was pleased to hear the announcement today of partial success in the recently completed Phase 3 trial in Thailand of a candidate HIV/AIDS vaccine owned by Sanofi-Aventis and Global Solutions for Infectious Diseases.

25 Sep 2009

Investigational vaccine shows modest potential for protecting against HIV infection

For the first time, scientists say an investigational vaccine has modest potential for protecting people against HIV infection, the Associated Press reports. "The vaccine — a combination of two previously unsuccessful vaccines — cut the risk of becoming infected with HIV by ... 31 percent in the world's largest [HIV] vaccine trial of more than 16,000 volunteers in Thailand, researchers announced Thursday in Bangkok," the news service writes (Marchione/Casey, 9/24).

25 Sep 2009

Experimental HIV vaccine shows promise

An experimental HIV vaccine raises hope of reducing the risk of infection. Wall Street Journal/Associated Press reports: "For the first time, an experimental vaccine has prevented infection with the AIDS virus, a watershed event in the deadly epidemic and a surprising result. Recent failures led many scientists to think such a vaccine might never be possible."

25 Sep 2009

NTMs: Rising cause of severe lung diseases

Nontuberculous mycobacteria (NTM) are environmental organisms found in both water and soil that can cause severe pulmonary (lung) disease in humans. Pulmonary NTM is on the rise in the United States, according to a large study of people hospitalized with the condition.

25 Sep 2009

H1N1 influenza pandemic could present a host of medical ethics issues: JCB

The anticipated onset of a second wave of the H1N1 influenza pandemic could present a host of thorny medical ethics issues best considered well in advance, according to the University of Toronto Joint Centre for Bioethics, which today released nine papers for public discussion.

25 Sep 2009

Researchers study functional similarity between zebrafish and humans to fight infections

Since the human response to infection is highly complex, research to understand how people fight infection is facilitated by studying how similar processes occur in simpler organisms. Zebrafish are becoming an important model for human disease, since they are easily handled, maintained and manipulated and many fundamental processes between zebrafish and humans are conserved.

24 Sep 2009

Mandell, Douglas, and Bennett's publication on infectious diseases released

Elsevier, the world-leading publisher of scientific, technical and medical information products and services, proudly announces the release of Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th Edition. Marking 30 years since its initial publication, it remains the most respected reference source of its kind, and maintains its relevance in the face of the emergence of newly recognized infectious diseases, including new strains of the swine (H1N1) and avian influenza viruses.

24 Sep 2009

Researchers to discuss ways to develop mathematical control theory methods for ABMs at NIMBioS workshop

Agent-based models (ABMs) are powerful computer-simulation modeling techniques that used increasingly to understand a broad range of biological phenomena, such as tumor growth, the immune system, and the spread of infectious diseases through a population.

24 Sep 2009

Merck, QIAGEN to collaborate to increase access to HPV vaccination and HPV DNA testing in developing countries

Merck & Co., Inc. and QIAGEN N.V. today announced their intent to collaborate on a new program to increase access to HPV vaccination and HPV DNA testing in some of the most resource-poor areas of the world.

From QIAGEN Manchester Limited 24 Sep 2009

NIH awards three UNC Scientists for high risk and innovative research

Three scientists from the University of North Carolina at Chapel Hill School of Medicine and the UNC Lineberger Comprehensive Cancer Center have received prestigious awards from the National Institutes of Health (NIH) aimed at encouraging "high risk" and innovative research.

24 Sep 2009

CEL-SCI Corporation engages a CRO for clinical trial of its investigational LEAPS-H1N1 treatment

CEL-SCI Corporation (NYSE AMEX: CVM), a developer of vaccines and therapeutics for the treatment of infectious diseases and a late-stage oncology company, announced today that it has hired a full-service Clinical Research Organization (CRO) with an office in the Washington, D.C./Baltimore area to support its conduct of the upcoming clinical trial of its investigational LEAPS-H1N1 treatment.

24 Sep 2009

It is possible to reduce the risk of HIV infection with a vaccine: AVAC

"Today marks an historic milestone in the search for an AIDS vaccine; we now have evidence that it is possible to reduce the risk of HIV infection with a vaccine," said AVAC executive director Mitchell Warren, reacting to the results of the first AIDS vaccine trial to ever show efficacy at preventing HIV. "It will take time and resources to fully analyze, understand and validate the data, but there is little doubt that this finding will energize and redirect the AIDS vaccine field as all of us begin the hard work to translate this landmark result into true public health benefit."

24 Sep 2009

Results of Phase III clinical trial of HIV vaccine released

A Phase III clinical trial involving more than 16,000 adult volunteers in Thailand has demonstrated that an investigational HIV vaccine regimen was safe and modestly effective in preventing HIV infection. According to final results released by the trial sponsor, the U.S. Army Surgeon General, the prime boost combination of ALVAC(R)( )HIV and AIDSVAX(R) B/E( )lowered the rate of HIV infection by 31.2% compared with placebo.

24 Sep 2009

Pregnant women must be vaccinated against H1N1 and seasonal flu

Pregnant women should be sure to get all their flu shots as soon as the vaccines become available this year to protect them against both the seasonal flu and the H1N1 (swine) flu, according to eight leading national maternal and infant health organizations.

24 Sep 2009

Global effort needed to protect people from species-crossing diseases, Report finds

A team of health experts on Tuesday called for the U.S. "to lead a global effort to protect people from new outbreaks of deadly infectious diseases that originate in animals, such as swine flu, AIDS and SARS," Reuters writes (Morgan, 9/22).

24 Sep 2009

Morphotek receives NIAID grant to develop human mAb therapies against staphylococcal-derived pathogens

Morphotek(R), Inc., a subsidiary of Eisai Corporation of North America, announced today that it was awarded $843,289 in funding from the National Institutes of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to support the development of human monoclonal antibody (mAb) therapies against staphylococcal-derived toxin(s).

23 Sep 2009

Dr. John Clarke polls more than 50,000 votes to win the 2009 H1N1 PSA contest

Department of Health and Human Services (HHS) Secretary Sebelius and Department of Education (ED) Secretary Arne Duncan today announced that Dr. John Clarke of Baldwin, N.Y., is the winner of the 2009 H1N1 PSA Contest. More than 50,000 votes were cast by Americans across the country on YouTube. Dr. Clarke will receive a $2,500 cash prize and his ad will be broadcast on national television.

23 Sep 2009

Report outlining global weaknesses in preventing deadly diseases

Significant weaknesses undermine the global community's abilities to prevent, detect early, and respond efficiently to potentially deadly species-crossing microbes, such as the pandemic H1N1 influenza virus sweeping the globe, says a new report from the Institute of Medicine and National Research Council. The report provides a detailed plan for establishing and funding a comprehensive, globally coordinated system to identify novel zoonotic disease threats as early as possible wherever they arise so appropriate measures can be taken to prevent significant numbers of human illnesses and deaths, and livestock losses.

23 Sep 2009

Report on species-crossing microbes and H1N1

23 Sep 2009

Chan calls for additional H1N1 vaccines for poor countries during WHO Asia-Pacific regional meeting

During the WHO Asia-Pacific regional meeting Monday, WHO Director-General Margaret Chan discussed the organization's efforts to ensure that poor nations have access to H1N1 vaccines, VOA News reports (Bayron, 9/21).

23 Sep 2009

Infectious Diseases News and Research

Partial success reported in the Phase 3 trial of HIV/AIDS vaccine

Investigational vaccine shows modest potential for protecting against HIV infection

Experimental HIV vaccine shows promise

NTMs: Rising cause of severe lung diseases

H1N1 influenza pandemic could present a host of medical ethics issues: JCB

Researchers study functional similarity between zebrafish and humans to fight infections

Mandell, Douglas, and Bennett's publication on infectious diseases released

Researchers to discuss ways to develop mathematical control theory methods for ABMs at NIMBioS workshop

Merck, QIAGEN to collaborate to increase access to HPV vaccination and HPV DNA testing in developing countries

NIH awards three UNC Scientists for high risk and innovative research

CEL-SCI Corporation engages a CRO for clinical trial of its investigational LEAPS-H1N1 treatment

It is possible to reduce the risk of HIV infection with a vaccine: AVAC

Results of Phase III clinical trial of HIV vaccine released

Pregnant women must be vaccinated against H1N1 and seasonal flu

Global effort needed to protect people from species-crossing diseases, Report finds

Morphotek receives NIAID grant to develop human mAb therapies against staphylococcal-derived pathogens

Dr. John Clarke polls more than 50,000 votes to win the 2009 H1N1 PSA contest

Report outlining global weaknesses in preventing deadly diseases

Report on species-crossing microbes and H1N1

Chan calls for additional H1N1 vaccines for poor countries during WHO Asia-Pacific regional meeting

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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