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Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how.

21 Jun 2016

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation.

21 Jun 2016

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Mothers of children with autism and were diagnosed with metabolic conditions during pregnancy, particularly gestational and type 2 diabetes, were more likely to have anti-fetal brain autoantibodies in their blood compared to healthy women of children with autism.

20 Jun 2016

Study finds link between chronic inflammation and premenstrual symptoms

Women with premenstrual symptoms (PMS) including mood swings, weight gain/bloating, and abdominal cramps/back pain have elevated levels of C-reactive protein (CRP), a biomarker of inflammation associated with increased risk of cardiovascular disease.

17 Jun 2016

FDA approves novel stomach-draining device to treat obesity

The U.S. Food and Drug Administration today approved a new obesity treatment device that uses a surgically-placed tube to drain a portion of the stomach contents after every meal.

15 Jun 2016

New FcMBL-based pathogen-detecting assay could rapidly detect systemic infections

To date, there are no methods that can quickly and accurately detect pathogens in blood to allow the diagnosis of systemic bloodstream infections that can lead to life-threatening sepsis.

15 Jun 2016

MicroRNA plays role in blocking development of arterial thrombosis

The dangers of arterial thrombosis - the formation of blood clots that can block arteries and cause illness or death - can escalate through a vicious cycle of coagulation and inflammation.

15 Jun 2016

Researchers find unexpected connection between two types of calming immune cells

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells.

15 Jun 2016

New technique may help replace brain cells, restore memory

Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function.

15 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jun 2016

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM).

13 Jun 2016

Researchers find link between specific genetic pathway and development of mouth ulcers in lupus patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE).

13 Jun 2016

Findings may help explain why rheumatoid arthritis drugs vary in effect

Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA.

12 Jun 2016

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

Intensifying current transplant conditioning to remove rather than suppress immune cells ahead of autologous haematopoietic stem cell transplantation may result in long-term remission of multiple sclerosis, phase II trial findings show.

10 Jun 2016

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge.

10 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

First limbal stem cell transplant performed in Ireland

On Tuesday 7th June 2016, the first Limbal Stem Cell transplant in Ireland was performed by Mr. William Power, Consultant Ophthalmologist at the Royal Victoria Eye and Ear Hospital in Dublin.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Type 1 diabetes occurs more frequently in patients with JIA

The results of a study involving more than 9,000 patients, presented today at the European League Against Rheumatism Annual Congress showed that Type 1 diabetes occurs significantly more frequently in patients with Juvenile Inflammatory Arthritis (JIA) than in the general population.

10 Jun 2016

Inflammation News and Research

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

E-cigarette use modifies gene expression important for upper airway immune defense

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Study finds link between chronic inflammation and premenstrual symptoms

FDA approves novel stomach-draining device to treat obesity

New FcMBL-based pathogen-detecting assay could rapidly detect systemic infections

MicroRNA plays role in blocking development of arterial thrombosis

Researchers find unexpected connection between two types of calming immune cells

New technique may help replace brain cells, restore memory

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

PET imaging can help identify autoimmune inflammation in MS

Anti-TNF therapy offers new hope to JDM patients

Researchers find link between specific genetic pathway and development of mouth ulcers in lupus patients

Findings may help explain why rheumatoid arthritis drugs vary in effect

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

New method helps speed up bacterial identification

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

First limbal stem cell transplant performed in Ireland

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

Type 1 diabetes occurs more frequently in patients with JIA

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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