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TSRI scientists discover new method for harnessing venoms for therapeutic use

There are lessons to be learned from venoms. Scorpions, snakes, snails, frogs and other creatures are thought to produce tens or even hundreds of millions of distinct venoms. These venoms have been honed to strike specific targets in the body.

26 May 2016

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Initiating antiretroviral therapy (ART) soon after diagnosis of an HIV infection did not prevent the progression of significant arterial inflammation in a small group of previously untreated patients.

26 May 2016

Pre-treatment with antihistamines may suppress gastrointestinal symptoms of food allergy

Simultaneous pre-treatment with antihistamines that block both the H1 and H4 antihistamine receptors suppressed the gastrointestinal symptoms of food allergy in mice, according to researchers at National Jewish Health.

26 May 2016

Common pain and anti-inflammation drugs may slow cancer growth

Scientists from the Florida campus of The Scripps Research Institute have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types of tumors.

26 May 2016

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

A group of researchers at Osaka University elucidated how a gene named Ly6/Plaur domain containing 8 (Lypd8) inhibits bacterial invasion of colonic epithelia, regulating intestinal inflammation. This achievement may lead to the development of drugs for ulcerative colitis.

25 May 2016

Too much of sun exposure may cause hangover

Summer is preparing to make its debut in a few weeks, and along with it, most of us will flock to the outdoors to soak up sunshine and Vitamin D.

25 May 2016

Single enzyme doing the work of a trio could offer precise way to treat diseases

Researchers identified a single enzyme doing the work of a trio thought necessary to control a common cellular signaling process being pursued as a therapeutic target.

24 May 2016

Study links low- and high-birthweight babies to increased cardiovascular disease risk

For reasons that remain unclear at least in the smaller babies, both birthweight extremes appear to increase the likelihood of early development of dangerous fat around major organs in the abdomen that significantly increases these risks, said Dr. Brian Stansfield, neonatologist at the Children's Hospital of Georgia and the Medical College of Georgia at Augusta University.

24 May 2016

Personalized DXM-loaded leukosomes may help treat inflammation

Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases.

24 May 2016

Rare mutation may reduce risk of developing arteriosclerosis by 34%

According to new international research, just less than one per cent of the population is naturally protected against developing chronic coronary artery diseases.

24 May 2016

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Patients with ulcerative colitis (UC) may improve their symptoms with a transplantation of healthy stool from donors, according to Australian researchers. The findings were presented by Dr Sudarchan Paramsothy MD, a gastroenterologist from the University of New South Wales, Australia at the Digestive Disease Week conference in San Diego, California between the 21st to 24th May.

24 May 2016

Heart failure patients who receive influenza vaccine less likely to develop dementia

Influenza vaccination is associated with a lower risk of dementia in patients with heart failure, according to a study in more than 20 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Ju-Chi Liu, director of the Division of Cardiovascular Medicine, Department of Medicine, Taipei Medical University - Shuang Ho Hospital, in New Taipei City, Taiwan.

24 May 2016

Researchers explore phenomenon that causes late mortality in sepsis patients

It's known that many patients die in the months and years after sepsis. But no one has known if this increased risk of death (in the 30 days to 2 years after sepsis) is because of sepsis itself, or because of the pre-existing health conditions the patient had before acquiring the complication.

24 May 2016

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Only 12% of kidney cancer patients with advanced disease survive five years after their initial treatment. In a Roswell Park Cancer Institute-led study, scientists report that some patients with advanced kidney cancer who continued to receive a novel immunotherapy drug after their disease progressed saw clinical benefit.

24 May 2016

Researchers identify trigger for immune cells' inflammatory response

Scientists at the University of Bristol have identified the trigger for immune cells' inflammatory response - a discovery that may pave the way for new treatments for many human diseases.

23 May 2016

Scientists take key step towards understanding link between obesity and physically distant diseases

Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis.

23 May 2016

New method helps scavenge inflammatory molecules that mediate sepsis in mice

Sepsis is a life-threatening complication of infection in which the molecules that the body releases to fight an infection trigger widespread inflammatory responses, resulting in damage to multiple organ systems.

22 May 2016

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment.

22 May 2016

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state.

21 May 2016

Researchers identify hCRTh2 protein as possible therapeutic target for asthma

Patients with asthma have chronic lung inflammation that results in sporadic narrowing of the airways and difficulty breathing. Symptoms and severity are variable among individuals; however, the cells and inflammatory factors that trigger asthmatic events have been fairly well characterized and are similar regardless of the asthma-inducing stimuli.

20 May 2016

Inflammation News and Research

TSRI scientists discover new method for harnessing venoms for therapeutic use

ART alone not sufficient to reduce arterial inflammation among HIV-infected patients, study finds

Pre-treatment with antihistamines may suppress gastrointestinal symptoms of food allergy

Common pain and anti-inflammation drugs may slow cancer growth

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

Too much of sun exposure may cause hangover

Single enzyme doing the work of a trio could offer precise way to treat diseases

Study links low- and high-birthweight babies to increased cardiovascular disease risk

Personalized DXM-loaded leukosomes may help treat inflammation

Rare mutation may reduce risk of developing arteriosclerosis by 34%

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Heart failure patients who receive influenza vaccine less likely to develop dementia

Researchers explore phenomenon that causes late mortality in sepsis patients

Ongoing treatment with nivolumab shows benefit in advanced kidney cancer patients

Researchers identify trigger for immune cells' inflammatory response

Scientists take key step towards understanding link between obesity and physically distant diseases

New method helps scavenge inflammatory molecules that mediate sepsis in mice

New collaborative research center to investigate promising aspects of mucosal immunology

Research provides pathway toward creation of first broad-spectrum antiviral drug

Researchers identify hCRTh2 protein as possible therapeutic target for asthma

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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