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Higher aortic stiffness associated with reduced white matter volume among young adults

A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle structural damage to the brain that is implicated in cognitive decline and Alzheimer's disease later in life.

29 Mar 2016

Study confirms involvement of immune system in CASPR2-associated encephalitis

The complement system, which forms part of our immune system, is involved in a special form of epilepsy. This is the conclusion of a recently published single-case study.

29 Mar 2016

Oral administration of cyclotide may improve symptoms of multiple sclerosis

MedUni Vienna has made a crucial development in the treatment of Multiple Sclerosis (MS): Together with his team and the research group led by Gernot Schabbauer, international partners from Australia, Germany and Sweden, Christian Gruber, Chief Researcher at the Center for Physiology and Pharmacology has demonstrated in an animal model that, following treatment with a specially synthesized plant peptide (cyclotide), there is no further progression of the usual clinical signs of multiple sclerosis.

29 Mar 2016

Protease inhibitors may prevent cardiovascular disease risk caused by HIV medications

According to the World Health Organization, approximately 37 million people are living with HIV. Antiviral medications are used to control the disease and prevent its progression to AIDS.

29 Mar 2016

Scientists identify two enzymes that appear to play role in metabolism, inflammation

A team led by scientists at The Scripps Research Institute and the Salk Institute for Biological Studies has discovered two enzymes that appear to play a role in metabolism and inflammation—and might someday be targeted with drugs to treat type 2 diabetes and inflammatory disorders.

29 Mar 2016

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

Gleevec could be novel therapeutic agent for type 2 diabetes

The cancer treatment drug Imatinib, otherwise known as Gleevec is approved to treat various forms of cancer, mostly notably chronic myeloid leukemia (CML). However, researchers have stumbled onto another possible use for it, curing type 2 diabetes.

28 Mar 2016

Changing one atom in InsP6 inhibitor can increase its ability to neutralize toxins in the gut

Infections with bacterium Clostridium difficile have rapidly become a significant medical problem in hospitals and long-term care facilities. The bacteria cause diarrhea and life-threatening inflammation of the colon by producing toxins that kill the endothelial cells that form the lining of the gut.

26 Mar 2016

Technically poor root fillings linked to stress and economy

Only half of all root fillings that are done in the Swedish public dental service are of good quality. The reason that dentists accept technically poor root fillings can be that they feel root fillings are difficult, associate them with stress and frustration as well as that a good quality root treatment often takes longer than what the dental care tariff allots as compensation.

25 Mar 2016

Researchers discover human equivalent DAMP protein in plants

A protein that signals tissue damage to the human immune system has a counterpart that plays a similar role in plants, report researchers at the Boyce Thompson Institute.

25 Mar 2016

Higher levels of BPA in pregnant mother's blood may contribute to preterm births

Higher concentrations of the common plastics chemical and environmental pollutant Bisphenol A, or BPA, in a pregnant mother's blood may be a contributing factor in preterm births, according to a new study from The University of Texas Medical Branch at Galveston.

25 Mar 2016

Air pollution can lead to premature death

People who live where there are high levels of air pollution have an increased risk of dying prematurely. Air pollution levels in Gothenburg have, however, decreased by half in the past few decades.

25 Mar 2016

Omega-6 fatty acids can reduce risk of type 2 diabetes

A new study from the University of Eastern Finland shows that high serum omega-6 polyunsaturated fatty acid concentrations are linked to a significantly reduced risk of type 2 diabetes. The findings were published in the American Journal of Clinical Nutrition.

24 Mar 2016

Engineered vaginal Lactobacilli could reduce heterosexual HIV-1 transmission in women

A normal, predominant bacterial species of the healthy vaginal microbiota can be engineered for potential use as a novel protective agent against HIV-1 transmission in women, according to a new publication from scientists at Osel, Inc. and their collaborators.

24 Mar 2016

Common parasitic infection linked to intermittent explosive disorder

In recent years, a common parasitic infection - as many as a third of the world's population may have it - has been linked to a range of psychiatric disorders, including schizophrenia and bipolar disorder, as well as behavioral dysregulation such as suicide attempts and car accidents.

24 Mar 2016

Retinal thickness points to disability worsening in MS patients

The thickness of the peripapillary retinal nerve fibre layer (pRNFL) may help to predict worsening disability in patients with multiple sclerosis (MS), optical coherence tomography (OCT) ...

24 Mar 2016

Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

Immunoproteasome inhibits repair function of alveolar macrophages

Scientists of Helmholtz Zentrum München, a partner in the German Center for Lung Research, have observed that the immunoproteasome inhibits the repair function of alveolar macrophages.

22 Mar 2016

Cutting-edge vascular implant technology available at PinnacleHealth for patients with claudication

PinnacleHealth CardioVascular Institute enrolled the first patient in Pennsylvania into the TOBA II clinical on October 19, 2015. This trial is to assess the safety and efficacy of a vascular implant for the treatment of dissections (tearing in the artery wall) that occur following balloon angioplasty (PTA) of the main artery in the leg.

22 Mar 2016

Stress management can cut risk of another heart attack by half

Patients recovering from heart attacks or other heart trouble could cut their risk of another heart incident by half if they incorporate stress management into their treatment, according to research from Duke Health.

22 Mar 2016

Inflammation News and Research

Higher aortic stiffness associated with reduced white matter volume among young adults

Study confirms involvement of immune system in CASPR2-associated encephalitis

Oral administration of cyclotide may improve symptoms of multiple sclerosis

Protease inhibitors may prevent cardiovascular disease risk caused by HIV medications

Scientists identify two enzymes that appear to play role in metabolism, inflammation

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

Gleevec could be novel therapeutic agent for type 2 diabetes

Changing one atom in InsP6 inhibitor can increase its ability to neutralize toxins in the gut

Technically poor root fillings linked to stress and economy

Researchers discover human equivalent DAMP protein in plants

Higher levels of BPA in pregnant mother's blood may contribute to preterm births

Air pollution can lead to premature death

Omega-6 fatty acids can reduce risk of type 2 diabetes

Engineered vaginal Lactobacilli could reduce heterosexual HIV-1 transmission in women

Common parasitic infection linked to intermittent explosive disorder

Retinal thickness points to disability worsening in MS patients

Cinqair (reslizumab) approved for treatment of severe asthma

Immunoproteasome inhibits repair function of alveolar macrophages

Cutting-edge vascular implant technology available at PinnacleHealth for patients with claudication

Stress management can cut risk of another heart attack by half

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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