Inflammation News and Research

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Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Scientists at Sanford Burnham Prebys Medical Discovery Institute have solved the atomic structure of a unique ubiquitin ligase complex. Ubiquitin is best known for its role in protein degradation, but more recently seen as important for cell signaling, DNA repair, anti-inflammatory, and immune responses.

21 Jan 2016

CSU's BioMARC awarded DoD contract to help develop new vaccines to combat encephalitic viruses

Colorado State University's Biopharmaceutical Manufacturing and Academic Resource Center has been awarded a 10-month, $4.6 million contract funded by the Department of Defense to help develop and manufacture new vaccines to fight encephalitic viruses that cause inflammation of the brain.

21 Jan 2016

MU School of Medicine researchers find link between varicella zoster virus vaccine and corneal inflammation

In use for more than 20 years, the varicella zoster virus vaccine for chickenpox and shingles is considered an essential medicine by the World Health Organization. However, researchers from the University of Missouri School of Medicine have found, in rare instances, a link between the vaccine and corneal inflammation.

21 Jan 2016

Study outlines new model to help predict age-related response to hepatitis B vaccine

Physicians have known for years that patients respond differently to vaccines as they age. There may soon be a new way to predict and enhance the effectiveness of vaccinations, in particular the hepatitis B vaccine.

20 Jan 2016

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

In results published on October 19, 2015 in the Journal of Lipid Research, a team of translational scientists at the Medical University of South Carolina report a new reason why non-alcoholic steatohepatitis (NASH) worsens in people who are obese.

20 Jan 2016

New study sheds light on possible role of ion channel in the immune system

Many cells have microscopic gates, called ion channels, which open to allow the flow of ions across the cell membrane. Thanks to these gates, cells can detect stimuli such as heat, pain, pressure and even spicy food.

20 Jan 2016

Phthalate DEHP could lead to weight gain

In cooperation with the Integrated Research and Treatment Center Adiposity Diseases at the University of Leipzig and the University Hospital Leipzig, researchers from the Helmholtz Centre for Environmental Research have now published a study in the PLOS ONE journal showing that the phthalate DEHP leads to weight gain and revealed the metabolic processes involved.

19 Jan 2016

Extended weekend sleep can counteract increased risk of diabetes associated with sleep loss

Two consecutive nights of extended sleep, a typical weekend occurrence, appears to counteract the increased risk of diabetes associated with short-term sleep restriction during the work week, at least in lean, healthy, young men eating a controlled diet.

19 Jan 2016

Scientists develop wireless brain sensors

A team of neurosurgeons and engineers has developed wireless brain sensors that monitor intracranial pressure and temperature and then are absorbed by the body, negating the need for surgery to remove the devices.

18 Jan 2016

PK molecule could be a target for vascular complications linked to type 1 diabetes

In an article published ahead of print on November 24, 2015 in the journal Diabetes (available at http://dx.doi.org/10.2337/db15-0930), researchers from the Medical University of South Carolina, the American University of Beirut, and Case Western Reserve University report that a molecule called pre-kallikrein (PK) could be a target for the vascular complications associated with type 1 diabetes.

18 Jan 2016

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants. Their findings clarify what prompts the inflammatory response that results in BPD, which previously had been unclear.

18 Jan 2016

Metamaterials could reduce MRI scanning times by more than 50%

A group of researchers from Russia, Australia and the Netherlands have developed a technology that can reduce Magnetic Resonance Imaging (MRI) scanning times by more than 50%, meaning hospitals can drastically increase the number of scans without changing equipment.

18 Jan 2016

MGH researchers find how metformin drug prevents progression of pancreatic cancer

Massachusetts General Hospital investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer.

17 Jan 2016

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Novartis announced today that the US Food and Drug Administration has approved Cosentyx (secukinumab) for two new indications - the treatment of adult patients with active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA).

17 Jan 2016

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

13 Jan 2016

OptMed obtains FDA 510(k) marketing clearance for topical skin adhesive

OptMed Inc., a medical device manufacturer, announced today that the Company received 510(k) marketing clearance from the US Food and Drug Administration for its BondEase product, a topical skin adhesive intended for the closure of surgical incisions and lacerations as an alternative to sutures and staples.

12 Jan 2016

New article suggests that playing American football may contribute to hypertension

As National Football League playoff games are underway, a new article published in the "Hypotheses" section of the January 2016 issue of The FASEB Journal, suggests that the toll the sport takes on players' bodies extends beyond head trauma and damage to limbs and joints. The trauma and damage associated with football participation may also be linked to elevations in blood pressure through immune system activation and inflammation.

12 Jan 2016

Blocking brain inflammation could protect against memory, behaviour changes

A University of Southampton-led study has found that blocking a receptor in the brain responsible for regulating immune cells could protect against the memory and behaviour changes seen in the progression of Alzheimer's disease.

11 Jan 2016

Intelligent Labs launches Ultra Pure Omega 3 fish oil in the UK

Intelligent Labs a premium supplement company today announced the launch in the UK of their Ultra Pure Omega 3, after launching in the US this summer to great success. They believe their Ultra Pure Omega 3 will be the strongest and most effective Omega 3 fish oil available in the UK.

11 Jan 2016

Intake of Bimuno in early life benefits brain development

Clasado Biosciences Limited, the producers and suppliers of Bimuno® (B-GOS), a unique patented trans-galactooligosaccharide complex, and the Department of Psychiatry, University of Oxford, today announce the results of their latest pre-clinical study, demonstrating for the first time a major role of B-GOS in modulating brain development at the molecular level in early life stages.

11 Jan 2016

Inflammation News and Research

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

CSU's BioMARC awarded DoD contract to help develop new vaccines to combat encephalitic viruses

MU School of Medicine researchers find link between varicella zoster virus vaccine and corneal inflammation

Study outlines new model to help predict age-related response to hepatitis B vaccine

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

New study sheds light on possible role of ion channel in the immune system

Phthalate DEHP could lead to weight gain

Extended weekend sleep can counteract increased risk of diabetes associated with sleep loss

Scientists develop wireless brain sensors

PK molecule could be a target for vascular complications linked to type 1 diabetes

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Metamaterials could reduce MRI scanning times by more than 50%

MGH researchers find how metformin drug prevents progression of pancreatic cancer

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Inflammation associated with elevated glutamate in the brain could guide depression treatments

OptMed obtains FDA 510(k) marketing clearance for topical skin adhesive

New article suggests that playing American football may contribute to hypertension

Blocking brain inflammation could protect against memory, behaviour changes

Intelligent Labs launches Ultra Pure Omega 3 fish oil in the UK

Intake of Bimuno in early life benefits brain development

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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