Inflammation News and Research

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Large doses of vitamin A reduce severity of gastrointestinal disease in mice

After observing that some gastrointestinal disease in premature human and mouse infants progresses only when certain immune system white blood cells go into inflammatory overdrive, Johns Hopkins researchers have found that giving large doses of vitamin A to mice converts those blood cells into inflammation suppressors and reduces the severity of the disease, compared to untreated mice.

22 Dec 2015

MD Anderson study reveals MDSCs as likely target for developing prostate cancer treatments

Immune suppressor cells called MDSCs (myeloid-derived suppressor cells) may be important in developing treatments for advanced prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center.

22 Dec 2015

Scientists identify 52 genetic variations associated with age-related macular degeneration

In one of the latest examples of precision medicine, teams of geneticists from nine countries, involving more than 100 scientists, analyzed the genes of more than 33,000 individuals in the hope of finding genetic variations responsible for age-related macular degeneration (AMD), the leading cause of vision loss among people age 50 or older.

22 Dec 2015

Small airway-on-a-chip enables analysis of human COPD and asthma

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), the third leading cause of mortality worldwide, and asthma can be studied outside the human body.

22 Dec 2015

UM student awarded grant for research on human immune system

A hardworking University of Montana undergraduate student will spend the next two and half years studying the hardest-working cell in the human immune system.

22 Dec 2015

Australian researchers develop new technique to combat chronic bacterial infections in hospitals

One of the scourges of infections in hospitals – biofilms formed by bacteria that stick to each other on living tissue and medical instruments, making them harder to remove – can be tricked into dispersing with the targeted application of nanoparticles and heat, researchers have found.

21 Dec 2015

Cardiff scientists find way to aid recovery, reduce risk of life-threatening infections in brain damaged patients

Cardiff University scientists believe they may have found a way to aid recovery and minimise the risk of life-threatening infections in patients with traumatic brain injuries.

17 Dec 2015

Scientists reveal major players in severe muscle damage caused by sepsis

Scientists from the Institut Pasteur, Paris Descartes University, Sainte-Anne Hospital and the CNRS have recently published a paper in Nature Communications in which they reveal major players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery.

17 Dec 2015

Oxford research programmes to explore link between metabolism, inflammation in metabolic diseases

Two innovative Oxford research programmes will explore the relationship between metabolism and inflammation in metabolic diseases. Obesity, insulin resistance, type 2 diabetes (T2D) and associated cardiovascular disease (CVD) -- all metabolic diseases -- are an epidemic global health problem.

17 Dec 2015

Researchers identify how immune cells triggered by recurrent Strep A infections affect the brain

Researchers have discovered how immune cells triggered by recurrent Strep A infections enter the brain, causing inflammation that may lead to autoimmune neuropsychiatric disorders in children.

16 Dec 2015

New study finds a reason for ethnic disparity in CF diagnoses

Cystic fibrosis (CF) occurs less frequently in nonwhites than in whites, and nonwhites tend to be diagnosed at a later age. This late diagnosis often comes only once they have become symptomatic, rather than through newborn screening programs or molecular diagnostic testing.

16 Dec 2015

Human-gut-on-a-chip model offers hope for patients suffering from IBD

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst can lead to life-threatening complications.

16 Dec 2015

WuXi forms strategic alliance with MedImmune to accelerate development of biologics portfolio in China

WuXi AppTec, a leading open-access R&D capability and technology platform company serving the global pharmaceutical, biotechnology, and medical device industries, announced today that it has formed a strategic alliance with MedImmune, the global biologics research and development arm of AstraZeneca.

16 Dec 2015

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

16 Dec 2015

U of T researchers find another clue in understanding the cause of MS

Researchers at the University of Toronto have found another clue in understanding the cause of what drives Multiple Sclerosis (MS) disease. Their findings were published today in Immunity.

16 Dec 2015

CytoSorbents partners with Hoang Long Pharma to bring CytoSorb to Vietnam

CytoSorbents Corporation, a leader in critical care immunotherapy commercializing its CytoSorb extracorporeal cytokine adsorber to control deadly inflammation using blood purification, today announced an exclusive multi-year distribution agreement with Hoang Long Pharma, a medical distributor in Vietnam specializing in the distribution of innovative pharmaceuticals, biologics, and devices to treat patients suffering from critical illnesses, immunologic disorders and deficiencies, and infections.

15 Dec 2015

African American men with clinical chronic prostatitis have lower risk of prostate cancer

According to a new study, African American men with clinical chronic prostatitis have a significantly lower risk of prostate cancer.

15 Dec 2015

Lupuzor may become first non-immunosuppressant therapy for lupus

Lupuzor may become the first specific and non-immunosuppressant therapy for lupus, a disabling autoimmune disease that is currently incurable.

15 Dec 2015

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Researchers from the University of Arkansas for Medical Sciences and other institutions are reporting the discovery of the first broad spectrum drug that can potently kill senescent (or aging) cells in culture and effectively clear the cells in animals by specifically targeting a pathway that is critical for the survival of senescent cells.

15 Dec 2015

New study examines antioxidant effects of pomegranate extract on cardiovascular risk factors

A new study assessing the antioxidant effects of pomegranate extract on cardiovascular risk factors and muscle function showed reductions in blood pressure and some atheroprotective benefits, but no effects on inflammation, oxidative strength, or muscle strength.

15 Dec 2015

Inflammation News and Research

Large doses of vitamin A reduce severity of gastrointestinal disease in mice

MD Anderson study reveals MDSCs as likely target for developing prostate cancer treatments

Scientists identify 52 genetic variations associated with age-related macular degeneration

Small airway-on-a-chip enables analysis of human COPD and asthma

UM student awarded grant for research on human immune system

Australian researchers develop new technique to combat chronic bacterial infections in hospitals

Cardiff scientists find way to aid recovery, reduce risk of life-threatening infections in brain damaged patients

Scientists reveal major players in severe muscle damage caused by sepsis

Oxford research programmes to explore link between metabolism, inflammation in metabolic diseases

Researchers identify how immune cells triggered by recurrent Strep A infections affect the brain

New study finds a reason for ethnic disparity in CF diagnoses

Human-gut-on-a-chip model offers hope for patients suffering from IBD

WuXi forms strategic alliance with MedImmune to accelerate development of biologics portfolio in China

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

U of T researchers find another clue in understanding the cause of MS

CytoSorbents partners with Hoang Long Pharma to bring CytoSorb to Vietnam

African American men with clinical chronic prostatitis have lower risk of prostate cancer

Lupuzor may become first non-immunosuppressant therapy for lupus

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

New study examines antioxidant effects of pomegranate extract on cardiovascular risk factors

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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