Inflammation News and Research

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Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

A medical records analysis by researchers at NYU Langone Medical Center concludes that physicians who treat severe acne leave too many patients on ineffective antibiotics for far too long before prescribing more potent needed therapy with the medication isotretinoin, sometimes known by its former brand name Accutane.

30 Oct 2015

Scientists one step closer to developing new treatment for inflammatory bowel disease

For patients with inflammatory bowel disease, the possibility of taking a single pill to bring long-lasting relief might seem too good to be true. Scientists at the Lewis Katz School of Medicine at Temple University are on the brink of making that happen, thanks to a recent proof-of-concept study, in which the severity of a form of inflammatory bowel disease in mice was dramatically reduced with one oral dose of a protein isolated from a bacterial biofilm.

30 Oct 2015

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Autophagy, literally self-eating or the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting it plays a role in guarding against the start of cancer, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

29 Oct 2015

Jet lag-like sleep disruptions promote memory problems, chemical alterations in the brain

Chemical changes in brain cells caused by disturbances in the body's day-night cycle may be a key underlying cause of the learning and memory loss associated with Alzheimer's disease, according to a University of California, Irvine study.

29 Oct 2015

Pre-clinical study demonstrates positive effects of advanced prebiotic on neuro-inflammation, anxiety

Clasado Biosciences Limited, the producers and suppliers of the second generation prebiotic Bimuno(R) (B-GOS), a unique trans-galactooligosaccharide, and the Department of Psychiatry, University of Oxford, today announce the results of their latest pre-clinical study demonstrating a major role of the unique carbohydrate complex Bimuno against neuro-inflammation and anxiety.

28 Oct 2015

New generation of incretin-based medicines allows coordinated action against diabesity

The new generation of incretin-based medicines will allow a coordinated action against the combination diabetes/obesity, also known as diabesity, in some cases with only a single weekly dose, and with the likelihood of additional beneficial effects on other health complications related to this condition, such as cardiovascular and neurodegenerative diseases.

28 Oct 2015

New, simpler surgical intervention not better than old method for treatment of intestinal perforation

A new and simpler surgical method for the treatment of intestinal perforation is a poorer alternative for patients compared to the old method, researchers at the University of Oslo and Akershus University Hospital find. The study raises important questions about the testing of new surgical methods.

28 Oct 2015

Hiroshima University researchers report promising new avenue for treating hepatitis B

A promising new avenue for treating hepatitis B has been reported by researchers at Hiroshima University who have developed a new animal model of the disease.

28 Oct 2015

Researchers identify role of cGAS enzyme in autoimmune diseases

Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.

28 Oct 2015

Stopping cholesterol medications before surgery may increase risk of death during recovery

Patients who stop taking cholesterol medications before surgery are following outdated recommendations, and significantly increasing their risk of death if they don't resume taking the medications within two days after surgery, according to a study of more than 300,000 patients being presented at the ANESTHESIOLOGY 2015 annual meeting.

28 Oct 2015

Weight and physical activity level matter in kids' ability to think

Weight and physical activity levels are both factors in a child's ability to acquire and use knowledge, a new study finds.

28 Oct 2015

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Work on a new anti-inflammatory drug developed from the medicinal/spice plant turmeric recently received funding from a $225,000 grant from the National Institutes of Health National Center for Complementary and Integrative Health.

28 Oct 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

Experts reveal link between excess body weight and colorectal cancer risk

Experts speaking at the 23rd United European Gastroenterology Week (UEG Week 2015) in Barcelona, Spain today revealed compelling evidence of the link between excess body weight and risk of colorectal cancer (CRC). John Mathers, Professor of Human Nutrition from the Institute of Cellular Medicine at Newcastle University in the UK presented data showing an overall increase of 18% in relative risk of CRC per 5 unit increase in BMI.

27 Oct 2015

New study identifies molecular mechanism that prevents immunotherapy drugs from killing off cancer

Immunotherapy treatments have proven wildly successful in treating some patients with cancer. But despite this success, the majority of patients do not respond to the treatments.

27 Oct 2015

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Medical professionals know that when a spouse dies, the surviving partner is at increased risk of suffering early mortality - but they don't entirely understand why. A new Rice University professor has received a $3.765 million R01 grant from the National Institutes of Health to embark on a five-year study of the connection between psychological and physiological responses to such extraordinary stress.

27 Oct 2015

Scientists decode central signal switch associated with epileptic seizures

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.

27 Oct 2015

UTMB researchers find mechanisms to determine when pregnant women go into labor

During the last few weeks of a woman's pregnancy, many keep an overnight bag ready to go at a moment's notice in case they begin to go into labor. They do this because there is no clear signal that labor is about to begin - before the body makes it abundantly clear that this process has started. Understanding the mechanisms that initiate this process is especially important when treating women at risk of going into labor early.

27 Oct 2015

Common steroid medication does not reduce risk of long-term pain after heart surgery

A common steroid medication does not ease long-term pain at the incision site made during open-heart surgery, according to results of a large multicenter randomized controlled trial being presented at the ANESTHESIOLOGY 2015 annual meeting.

26 Oct 2015

CHMP recommends approval of Cosentyx in Europe to treat patients with AS and PsA, says Novartis

Novartis announced today that the Committee for Medicinal Products for Human Use has recommended the approval of Cosentyx (secukinumab) in Europe to treat ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients.

26 Oct 2015

Inflammation News and Research

Physicians leave severe acne patients on ineffective antibiotics for too long before prescribing more potent drug

Scientists one step closer to developing new treatment for inflammatory bowel disease

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Jet lag-like sleep disruptions promote memory problems, chemical alterations in the brain

Pre-clinical study demonstrates positive effects of advanced prebiotic on neuro-inflammation, anxiety

New generation of incretin-based medicines allows coordinated action against diabesity

New, simpler surgical intervention not better than old method for treatment of intestinal perforation

Hiroshima University researchers report promising new avenue for treating hepatitis B

Researchers identify role of cGAS enzyme in autoimmune diseases

Stopping cholesterol medications before surgery may increase risk of death during recovery

Weight and physical activity level matter in kids' ability to think

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Lithium chloride could offer effective treatment against osteoarthritis

Experts reveal link between excess body weight and colorectal cancer risk

New study identifies molecular mechanism that prevents immunotherapy drugs from killing off cancer

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Scientists decode central signal switch associated with epileptic seizures

UTMB researchers find mechanisms to determine when pregnant women go into labor

Common steroid medication does not reduce risk of long-term pain after heart surgery

CHMP recommends approval of Cosentyx in Europe to treat patients with AS and PsA, says Novartis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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