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Many pediatric chest X-rays unnecessary, offer no clinical benefit

Researchers at Mayo Clinic found that some children are receiving chest X-rays that may be unnecessary and offer no clinical benefit to the patient, according to a study presented today at the annual meeting of the Radiological Society of North America.

3 Dec 2014

New therapeutic targets can prevent scarring within transplanted kidneys

Kidneys donated by people born with a small variation in the code of a key gene may be more likely, once in the transplant recipient, to accumulate scar tissue that contributes to kidney failure, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published today in the Journal of Clinical Investigation.

2 Dec 2014

Ligand indazole chloride improves motor function, study shows

Multiple sclerosis (MS), an autoimmune disease of the brain and spinal cord, affects about 2.3 million people worldwide (400,000 in the United States). Affecting more women than men, it can be seen at any age, although it is most commonly diagnosed between the ages of 20 and 40.

2 Dec 2014

New approach can prevent chronic marijuana use, relieve mood, anxiety disorders

Replenishing the supply of a molecule that normally activates cannabinoid receptors in the brain could relieve mood and anxiety disorders and enable some people to quit using marijuana, a Vanderbilt University study suggests.

2 Dec 2014

Component of Glycyrrhiza uralensis plant may thwart development of metabolic disorders

New research published in the December 2014 issue of the Journal of Leukocyte Biology, shows that a component found in in the plant, Glycyrrhiza uralensis, may inhibit the development of metabolic disorders by stopping the activation of NLRP3, a protein involved in the disease process.

2 Dec 2014

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Alport Syndrome was first described by a physician called Cecil Alport, back in the late 1920s. It's a genetic disease that affects a certain type of collagen involved in the functioning of the kidney, the ear, and the eye.

1 Dec 2014

Promising new therapeutic strategy for chronic kidney disease

Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease's progress towards kidney failure. Now, however, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania, has found an aspect of CKD's development that points to a promising new therapeutic strategy.

1 Dec 2014

Drinking 3-5 cups of coffee per day may protect against Alzheimer’s Disease

Drinking 3-5 cups of coffee per day may help to protect against Alzheimer’s Disease, according to research highlighted in an Alzheimer Europe session report published by the Institute for Scientific Information on Coffee, a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health.

29 Nov 2014

Persistent eosinophilia common in COPD

More than one-third of patients with chronic obstructive pulmonary disease have persistent eosinophilia, researchers report in the European Respiratory Journal.

27 Nov 2014

Better evidence needed for relationship between exercise and COPD

Researchers call for high-quality studies investigating the relationship between physical activity and chronic obstructive pulmonary disease after their systematic review found the level of evidence to be poor.

27 Nov 2014

US Special Forces funding breakthrough drug therapy for treating wounded soldiers

US Special Forces are funding a world first, breakthrough drug therapy for treating battle casualties that's being developed by James Cook University scientists in Australia.

27 Nov 2014

Therapeutic nanoparticle safe, effective against H. pylori infection, shows study

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.

27 Nov 2014

European scientists develop, test drug that could reduce harmful side-effects of 'binge drinking'

A drug that could reduce the harmful side-effects of 'binge drinking', especially by teenagers, has been successfully developed and tested by a team of European scientists, including the University of Huddersfield's Professor Mike Page and Dr Karl Hemming. There is also the potential for new ways to treat Alzheimer's and other neurological diseases that damage the brain.

27 Nov 2014

Researchers say that nervous system may play vital role in infections, autoimmune diseases

The nervous system may play a bigger role in infections and autoimmune diseases than previously known. If researchers can learn more about that role, it could provide insight into diagnosing and treating everything from the stomach flu to rheumatoid arthritis.

27 Nov 2014

BWH researchers identify two-faced role of TIM-3 protein

A Brigham and Women's Hospital-led team has identified a long sought-after partner for a key immune protein, called TIM-3, that helps explain its two-faced role in the immune system -- sometimes dampening it, other times stimulating it. This newly identified partner not only sheds light on the inner workings of the immune system in diseases such as HIV, autoimmunity, and cancer, but also provides a critical path toward the development of novel treatments that target TIM-3.

26 Nov 2014

TSRI scientists find simple method to convert human skin cells into sensory neurons

A team led by scientists from The Scripps Research Institute has found a simple method to convert human skin cells into the specialized neurons that detect pain, itch, touch and other bodily sensations. These neurons are also affected by spinal cord injury and involved in Friedreich's ataxia, a devastating and currently incurable neurodegenerative disease that largely strikes children.

25 Nov 2014

New approach to fighting breast, thyroid cancers

A team of researchers from the University of Alberta has discovered a new approach to fighting breast and thyroid cancers by targeting an enzyme they say is the culprit for the "vicious cycle" of tumour growth, spread and resistance to treatment.

24 Nov 2014

NUS researchers make breakthrough discovery that could lead to future treatment for multiple sclerosis

A multi-disciplinary research team from the National University of Singapore has made a breakthrough discovery of a new type of immune cells that may help in the development of a future treatment for multiple sclerosis (MS).

24 Nov 2014

Researchers say that promoting healthy gut microbiota can help treat metabolic syndrome

Promoting healthy gut microbiota, the bacteria that live in the intestine, can help treat or prevent metabolic syndrome, a combination of risk factors that increases a person's risk for heart disease, diabetes and stroke, according to researchers at Georgia State University and Cornell University.

24 Nov 2014

BIDMC's George Tsokos receives two prestigious awards at 2014 ACR Annual Scientific Meeting

George Tsokos, MD, Chief of Rheumatology at Beth Israel Deaconess Medical Center and a national leader in the field of lupus research was honored by both the Lupus Foundation of America and the American College of Rheumatology with two prestigious awards presented during the 2014 ACR Annual Scientific Meeting recently held in Boston.

23 Nov 2014

Inflammation News and Research

Many pediatric chest X-rays unnecessary, offer no clinical benefit

New therapeutic targets can prevent scarring within transplanted kidneys

Ligand indazole chloride improves motor function, study shows

New approach can prevent chronic marijuana use, relieve mood, anxiety disorders

Component of Glycyrrhiza uralensis plant may thwart development of metabolic disorders

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Promising new therapeutic strategy for chronic kidney disease

Drinking 3-5 cups of coffee per day may protect against Alzheimer’s Disease

Persistent eosinophilia common in COPD

Better evidence needed for relationship between exercise and COPD

US Special Forces funding breakthrough drug therapy for treating wounded soldiers

Therapeutic nanoparticle safe, effective against H. pylori infection, shows study

European scientists develop, test drug that could reduce harmful side-effects of 'binge drinking'

Researchers say that nervous system may play vital role in infections, autoimmune diseases

BWH researchers identify two-faced role of TIM-3 protein

TSRI scientists find simple method to convert human skin cells into sensory neurons

New approach to fighting breast, thyroid cancers

NUS researchers make breakthrough discovery that could lead to future treatment for multiple sclerosis

Researchers say that promoting healthy gut microbiota can help treat metabolic syndrome

BIDMC's George Tsokos receives two prestigious awards at 2014 ACR Annual Scientific Meeting

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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