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Research: Architecture of DNA maintained by protein ANP32E

A team of scientists from the National Cancer Centre Singapore (NCCS), the Institut de G-n-tique et de Biologie Moleculaire et Cellulaire (Strassbourg France), and the Institut Albert Bonniot (Grenoble, France) have made an important finding on how genes are regulated. This study will be released in the January 30th, 2014 print issue of the journal Nature.

27 Jan 2014

Cleveland Clinic: Process that turns HDL cholesterol bad discovered

Cleveland Clinic researchers have discovered the process by which high-density lipoprotein (HDL) - the so-called "good cholesterol" - becomes dysfunctional, loses its cardio-protective properties, and instead promotes inflammation and atherosclerosis, or the clogging and hardening of the arteries.

26 Jan 2014

Increased inflammation following infection impairs brain's ability to form spatial memories

Increased inflammation following an infection impairs the brain's ability to form spatial memories - according to new research. The impairment results from a decrease in glucose metabolism in the brain's memory centre, disrupting the neural circuits involved in learning and memory.

25 Jan 2014

NICE approves MabThera for treating severe forms of GPA and MPA

Today the National Institute for Health and Care Excellence has approved the use of MabThera for two potentially life-threatening auto-immune diseases, GPA and MPA, which result in the inflammation and damage of small blood vessels and frequently involve multiple organs. The two diseases affect over 13,000 people in the UK and are characterised by the breaking down of specific areas of tissue in the body that, if not treated, can lead to organ damage, organ failure and even death.

24 Jan 2014

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

A study of the metabolic effects of omega-3 fatty acids, especially DHA, concludes that these compounds may have an even wider range of biological impacts than previously considered, and suggests they could be of significant value in the prevention of fatty liver disease.

24 Jan 2014

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

Extracts from the birch tree have served for centuries as a traditional means of helping the damaged skin around wounds to regenerate more quickly. Prof. Dr. Irmgard Merfort from the Institute of Pharmaceutical Sciences of the University of Freiburg and her team have now explained the molecular mechanism behind the wound-healing effect of an extract from the outer white layer of the tree's bark.

24 Jan 2014

Salmonella infections can reduce incidence of asthma, say researchers

Researchers from Germany have identified the mechanism by which Salmonella infections can reduce the incidence of asthma in mice. The research, which appears ahead of print in the journal Infection and Immunity, opens up new avenues of research that could lead to treatments.

24 Jan 2014

FDA grants final approval for Hi-Tech Pharmacal's Bromfenac Ophthalmic Solution ANDA

Hi-Tech Pharmacal Co., Inc., a specialty pharmaceuticals company, announced today that the US Food and Drug Administration, granted final approval for the Company's Abbreviated New Drug Application, for Bromfenac Ophthalmic Solution, 0.09% (Once-A-Day), the generic for ISTA Pharmaceuticals' Bromday ophthalmic solution, 0.09%.

23 Jan 2014

New study identifies correlation between cranberry juice consumption and healthy body composition

As the New Year kicks off and resolutions become reality, cranberry juice lovers can feel good knowing their favorite cranberry products are the perfect solution to a healthy 2014. A recent study published in Nutrients, a peer-reviewed scientific journal published by MDPI, identified a correlation between cranberry juice consumption and healthy body composition. The study joins the list of mounting evidence highlighting the fruit's exceptional health benefits, giving consumers one more reason to feel good about enjoying the festive fruit every day, everywhere, every way.

23 Jan 2014

CWRU researchers receive NIAID grant to conduct HIV research and clinical trials

AIDS researchers from Case Western Reserve University and University Hospitals Case Medical Center have received a seven-year funding award from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

23 Jan 2014

ECMO: A last-resort therapy for extremely severe cases of influenza

Physicians at the University of Alabama at Birmingham are employing a technology known as ECMO as a last-resort therapy for extremely severe cases of influenza. ECMO, short for extracorporeal membrane oxygenation, is a sort of portable heart/lung bypass machine.

23 Jan 2014

NPS MedicineWise urges parents to ensure that children's vaccinations are up to date

Following a recent spate of measles cases being reported in a number of Australian states, NPS MedicineWise is reminding parents to check whether their children’s immunisations are up to date before they head back to school next week.

22 Jan 2014

Scientists showcase HDL nanotherapy that may provide solution to repeat heart attacks

Up to 30 percent of heart attack patients suffer a new heart attack because cardiologists are unable to control inflammation inside heart arteries - the process that leads to clots rupturing and causing myocardial infarction or stroke.

22 Jan 2014

Scientists identify channel that acts as 'brake', limiting spontaneous pain

Scientists have identified a channel present in many pain detecting sensory neurons that acts as a 'brake', limiting spontaneous pain. It is hoped that the new research, published today [22 January] in the Journal of Neuroscience, will ultimately contribute to new pain relief treatments.

22 Jan 2014

Levels of depression and anxiety are higher in people with severe rheumatoid arthritis

Levels of depression and anxiety in people with severe rheumatoid arthritis are higher than previously reported, according to new research. As a result of their findings, a multi-centre team led by researchers at the Arthritis Research UK Centre for Genetics and Genomics at the University of Manchester, say that patients with severe active disease, who are waiting to go onto a biological therapy, should be routinely screened for depression by their doctors.

From The University of Manchester 21 Jan 2014

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Normally, tissue injury triggers a mechanism in cells that tries to repair damaged tissue and restore the skin to a normal, or homeostatic state. Errors in this process can give rise to various problems, such as chronic inflammation, which is a known cause of certain cancers.

21 Jan 2014

New technology may provide solution to high risk of repeat heart attacks, say scientists

Up to 30 percent of heart attack patients suffer a new heart attack because cardiologists are unable to control inflammation inside heart arteries — the process that leads to clots rupturing and causing myocardial infarction or stroke.

20 Jan 2014

Going barefoot contributes to hookworm infections

Going barefoot in parts of Africa, Asia and South America contributes to hookworm infections, which afflict an estimated 700 million of the world's poor. The parasitic worm lives in the soil and enters the body through the feet. By feeding on victims' blood, the worms cause anemia and, in children, stunted growth and learning problems.

20 Jan 2014

Researchers identify protein in brain that plays critical role in memory loss seen in Alzheimer's patients

Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted online today.

20 Jan 2014

Research may lead to potential treatment for deadly bacterial infections

Collaboration between the National University of Singapore (NUS) and The Hebrew University of Jerusalem (HUJ) on inflammation research may lead to a potential treatment for deadly bacterial infections

20 Jan 2014

Inflammation News and Research

Research: Architecture of DNA maintained by protein ANP32E

Cleveland Clinic: Process that turns HDL cholesterol bad discovered

Increased inflammation following infection impairs brain's ability to form spatial memories

NICE approves MabThera for treating severe forms of GPA and MPA

Omega-3 fatty acids especially DHA may have even wider range of biological impacts, shows study

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

Salmonella infections can reduce incidence of asthma, say researchers

FDA grants final approval for Hi-Tech Pharmacal's Bromfenac Ophthalmic Solution ANDA

New study identifies correlation between cranberry juice consumption and healthy body composition

CWRU researchers receive NIAID grant to conduct HIV research and clinical trials

ECMO: A last-resort therapy for extremely severe cases of influenza

NPS MedicineWise urges parents to ensure that children's vaccinations are up to date

Scientists showcase HDL nanotherapy that may provide solution to repeat heart attacks

Scientists identify channel that acts as 'brake', limiting spontaneous pain

Levels of depression and anxiety are higher in people with severe rheumatoid arthritis

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

New technology may provide solution to high risk of repeat heart attacks, say scientists

Going barefoot contributes to hookworm infections

Researchers identify protein in brain that plays critical role in memory loss seen in Alzheimer's patients

Research may lead to potential treatment for deadly bacterial infections

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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