Inflammation News and Research

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Inflammatory burden increased in overweight bipolar disorder patients

Breakdown of the amino acid tryptophan is increased in euthymic, overweight individuals with bipolar disorder, show preliminary results from the BIPFAT study.

20 Dec 2013

Joint initiative aims to eradicate health disparities among communities of color in the U.S.

The world's first and largest group medical practice and one of the nation's premier volunteer service organizations of professional African American women are joining forces to eradicate health disparities among communities of color in the United States. Mayo Clinic and The Links, Incorporated have established a formal collaboration that aims to develop a more diverse health care workforce.

20 Dec 2013

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Saint Louis University researchers have analyzed the microbiomes of people with chronic rhinosinusitis and healthy volunteers and found evidence that some chronic sinus issues may be the result of inflammation triggered by an immune response to otherwise harmless microorganisms in the sinus membranes.

20 Dec 2013

Researchers reveal how metabolic system breaks down in obesity

Researchers at University of Michigan have illuminated an aspect of how the metabolic system breaks down in obesity. The findings provide additional evidence that a drug entering clinical trials at the university could reverse obesity, Type 2 diabetes and fatty liver disease in humans.

20 Dec 2013

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

Obesity, alcoholism, and chronic hepatitis all increase the risk of getting liver cancer, which is the third leading cause of cancer death worldwide. Obesity in particular is driving a significant increase in liver cancer in the United States.

20 Dec 2013

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

Takeda Pharmaceutical Company Limited and Natrogen Therapeutics International, Inc. jointly announced today an agreement whereby Takeda will acquire an exclusive license to develop Natrogen's Natura-alpha compound as well as an option to acquire Natrogen. Natura-alpha is a synthetic small molecule oral compound that is believed to inhibit pro-inflammatory cytokine expression, which may help to reduce gastrointestinal inflammation. Natura-alpha is currently in Phase 2 development for the treatment of ulcerative colitis.

20 Dec 2013

UVA earns national award for video detailing efforts to improve quality of care for children with asthma

For a video detailing efforts to improve the quality of care for children with asthma, University of Virginia Health System has earned a national award from the Robert Wood Johnson Foundation (RWJF).

19 Dec 2013

UT Southwestern receives $10M grant to find effective treatments for alcoholic hepatitis

UT Southwestern Medical Center has launched the local arm of a national, multicenter study aimed at finding more effective treatments for alcoholic hepatitis, a disease of the liver that often leads to cirrhosis and death in severe cases.

19 Dec 2013

New study aims to identify breast cancer patients most susceptible to post-treatment fatigue

Although the prevalence and impact of cancer-related fatigue has been well established, very little is known about its predictors, mechanisms for development, and persistence post-treatment. A new research study at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in partnership with UCLA, is aimed at identifying breast cancer patients most susceptible to post-treatment fatigue by measuring biological, behavioral and social risk factors.

19 Dec 2013

Study reveals why people are predisposed to cardiovascular disease and death

A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists at Duke Medicine report.

19 Dec 2013

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

People with intermittent explosive disorder — a psychiatric illness characterized by impulsivity, hostility and recurrent aggressive outbursts — have elevated levels of two markers of systemic inflammation in their blood, according to a study involving nearly 200 subjects.

19 Dec 2013

Researchers develop potential treatment for atherosclerosis

Researchers at Emory and Georgia Tech have developed a potential treatment for atherosclerosis that targets a master controller of the process.

18 Dec 2013

UCLA researchers find no evidence of association between iron levels and atherosclerosis risk

A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S.

18 Dec 2013

Decreasing levels of reactive oxygen species can break cycle of unhealing wounds

Chronic wounds affect an estimated 6.5 million Americans at an annual cost of about $25 billion. Further, foot blisters and other diabetic ulcers or sores account for the vast majority of foot and leg amputations in the United States today.

18 Dec 2013

Measuring changes in certain proteins may better predict the progression of ALS

Measuring changes in certain proteins -- called biomarkers -- in people with amyotrophic lateral sclerosis may better predict the progression of the disease, according to scientists at Penn State College of Medicine.

17 Dec 2013

Researchers discover control mechanism that can trigger development of MDS

Researchers at the Moffitt Cancer Center have discovered a control mechanism that can trigger the development of myelodysplastic syndromes (MDS), a group of blood cancers. This finding may lead to therapies capable of preventing the progression of these diseases.

17 Dec 2013

Exposure to dust from homes with dogs may alter immune response to allergens

A new study suggests that exposure to dust from homes with dogs may alter the immune response to allergens and other asthma triggers by affecting the composition of the gut microbiome-the community of microbes that naturally colonize the digestive tract.

17 Dec 2013

Atara Biotherapeutics secures $38.5M in initial closings under Series B financing

Atara Biotherapeutics, Inc., a drug development company with a focus on innovative therapies for patients with debilitating diseases, announced today that it has secured $38.5 million in initial closings under its Series B financing. In this round, investors Amgen Ventures, Celgene Corporation, and EcoR1 Capital, joined existing investors Alexandria Venture Investments, DAG Ventures, Domain Associates, and Kleiner Perkins Caufield & Byers.

17 Dec 2013

Scientists identify protein complex essential for jumpstarting immune response during infection

St. Jude Children's Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the scientific journal Immunity.

17 Dec 2013

Utah researchers discover naturally occurring genetic variation that cause inflammatory arthritis

University of Utah researchers have discovered a naturally occurring genetic variation in mice that predisposes carriers toward developing severe, inflammatory arthritis. The finding implicates a new class of genes in arthritis progression, potentially opening doors to new treatment options.

17 Dec 2013

Inflammation News and Research

Inflammatory burden increased in overweight bipolar disorder patients

Joint initiative aims to eradicate health disparities among communities of color in the U.S.

Study supports mounting evidence that inflammation may be the cause of chronic rhinosinusitis

Researchers reveal how metabolic system breaks down in obesity

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

Takeda to acquire exclusive license to develop Natrogen's Natura-alpha compound

UVA earns national award for video detailing efforts to improve quality of care for children with asthma

UT Southwestern receives $10M grant to find effective treatments for alcoholic hepatitis

New study aims to identify breast cancer patients most susceptible to post-treatment fatigue

Study reveals why people are predisposed to cardiovascular disease and death

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

Researchers develop potential treatment for atherosclerosis

UCLA researchers find no evidence of association between iron levels and atherosclerosis risk

Decreasing levels of reactive oxygen species can break cycle of unhealing wounds

Measuring changes in certain proteins may better predict the progression of ALS

Researchers discover control mechanism that can trigger development of MDS

Exposure to dust from homes with dogs may alter immune response to allergens

Atara Biotherapeutics secures $38.5M in initial closings under Series B financing

Scientists identify protein complex essential for jumpstarting immune response during infection

Utah researchers discover naturally occurring genetic variation that cause inflammatory arthritis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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