Inflammatory Disease News and Research

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New drug protects nerve cells from damage in mice

Multiple sclerosis (MS) is a chronic inflammatory disease of the brain and spinal cord. Individuals with MS develop progressive neurological disability, and this is thought to be caused by degradation of the nerve cells.

14 Mar 2008

Turning off rogue macrophages

University of Pennsylvania scientists studying macrophages, the biological cells that spring from white blood cells to eat and destroy foreign or dying cells, have discovered how these "policemen" differentiate between friend and foe.

12 Mar 2008

A quarter of teenage girls in the U.S. have a sex-related disease

The Centers for Disease Control and Prevention (CDC) in the United States has revealed that a quarter of teen girls have a sex-related disease.

11 Mar 2008

Discovery of new protein family that may play an important role in preventing inflammatory diseases

A University of Central Florida research team has discovered a new protein family that may play an important role in preventing inflammatory diseases such as arthritis, some forms of cancer and even heart disease.

11 Mar 2008

Potential new gene therapy strategy for muscle-wasting diseases

Investigators in The Research Institute at Nationwide Children's Hospital have identified the role of a protein that could potentially lead to new clinical treatments to combat musculoskeletal diseases, including Duchenne muscular dystrophy (DMD).

11 Mar 2008

FDA approves Arcalyst for treatment of rare inflammatory syndromes

The U.S. Food and Drug Administration has approved a drug to help ease the suffering faced by those with certain chronic inflammatory diseases.

28 Feb 2008

Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

New research from the UC Davis M.I.N.D. Institute shows that an interaction between fetal brain cells and maternal antibodies could be linked with the repetitive behavior - also called stereotypies - that is characteristic of autism.

12 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

Protein, macrophage migration inhibitory factor predicts heart attack response and cardiac damage

A protein has been found that influences the response of the heart to a lack of oxygen and blood flow, such as occurs during a heart attack, a team of Yale School of Medicine researchers report in Nature.

4 Feb 2008

Vaginal probiotic product reduce recurrence rate of bacterial vaginosis

A newly published double blind, randomised, placebo controlled study(1) shows that EcoVag, a patented vaginal probiotic product from the Danish company, Bifodan, significantly reduces the recurrence rate of Bacterial Vaginosis (BV) following antibiotic treatment.

31 Jan 2008

Unexpected protein-protein interaction suggests new ALS drug target

Discovery of an unexpected protein-protein interaction has led University of Iowa scientists and colleagues to identify a drug that slows the progression of Amyotrophic Lateral Sclerosis (ALS) in mice and nearly doubles the animals' lifespan.

25 Jan 2008

International team pinpoints the genes for lupus

An international team of researchers has pinpointed the genes involved in the auto-immune system disease lupus.

21 Jan 2008

Common variations in human DNA signal lupus risk

Scientists have pinpointed a set of common variations in human DNA that signal a higher risk for lupus in women who carry them.

21 Jan 2008

Arthritis drug Etanercept clears up symptoms of psoriasis

New research from the United States has found that a drug commonly used to treat arthritis significantly reduces the symptoms of psoriasis in children.

20 Jan 2008

Supplements of lipoic acid could reduce atherosclerosis, weight gain

A new study done with mice has discovered that supplements of lipoic acid can inhibit formation of arterial lesions, lower triglycerides, and reduce blood vessel inflammation and weight gain - all key issues for addressing cardiovascular disease.

15 Jan 2008

Growing burden of arthritis in the U.S.

Arthritis is the most common cause of disability in the United States. Over the next 25 years as the Baby Boom generation continues to age, the toll of this disease will escalate.

3 Jan 2008

Severe psoriasis can cut short life

According to a new study having some forms of psoriasis can shorten a person's lifespan.

19 Dec 2007

Discovery of key mechanism underlying idiopathic pulmonary fibrosis

A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment.

13 Dec 2007