Inflammatory Disease News and Research

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Vaccines show link between periodontal and heart disease

Strengthening the link between periodontal and heart disease, researchers at Boston University School of Medicine (BUSM) found they can prevent mice from developing P. gingivalis-accelerated heart disease by immunizing the mice with a vaccine that protects against periodontal disease.

6 May 2004

Study identifies key factor causing low iron and anemia in patients with infections and major inflammatory diseases

UCLA researchers found that a member of the immune system’s defense team stimulates a chain reaction leading to chronic anemia in many patients with infections and major inflammatory diseases.

3 May 2004

Researchers show link between periodontal and heart disease

3 May 2004

Drug-resistant gonorrhea is a major public health concern

The increasing resistance to fluoroquinolones effectively eliminates an entire class of antibiotics and leaves only one class of drugs -- cephalosporins -- as the first-line therapy in the treatment of gonorrhea. There are currently no other major groups of antibiotics left to treat gonorrhea.

2 May 2004

Chlamydia may cause infertility in men as well as long-term health problems for women

Swedish study suggests Chlamydia the most common sexually transmitted infection might cause infertility in men as well as long-term health problems for women.

29 Apr 2004

Study of an oral fumarate shows improvement in psoriasis

Biogen Idec and Fumapharm AG today announced results from a Phase II study of BG-12, an oral fumarate, in patients with severe psoriasis.

29 Apr 2004

New research findings about T-cell transport shed light on immune system

New research findings about T-cell transport shed light on how the normal immune system functions and could have implications in fighting autoimmune and inflammatory diseases, say researchers at University of Texas Southwestern Medical Center, Dallas.

20 Apr 2004

Gene discovery could improve anemia treatment in patients

Patients with inflammatory diseases such as arthritis, chronic infections and some types of cancer, often become anemic – a condition called anemia of chronic disease (ACD). While ACD rarely kills patients, it can make their lives miserable.

18 Apr 2004

Collaboration to create a series of small molecule drugs leads against a Takeda target

Array BioPharma Inc. today announced the commencement of a drug discovery collaboration with Takeda Chemical Industries, Ltd. to create a series of small molecule drug leads against a Takeda target. This collaboration is in addition to Array's existing research agreement with Takeda that began in 2001.

5 Apr 2004

World’s largest biotechnology company acquires Tularik

Amgen Inc., the world’s largest biotechnology company, and Tularik Inc., a pioneer in drug discovery related to cell signaling and the control of gene expression, today jointly announced that they have signed a definitive merger agreement whereby Tularik will become a wholly-owned subsidiary of Amgen in a stock for stock transaction.

30 Mar 2004

Raptiva, 20 percent improvement in an individual's signs and symptoms of arthritis.

Genentech, Inc. and XOMA Ltd. today announced preliminary results of a randomized, placebo-controlled Phase II study with RAPTIVA™ (efalizumab) in 107 patients with psoriatic arthritis. The study did not reach statistical significance at 12 weeks (84 days) for the primary endpoint, ACR 20 response. An ACR 20 response indicates at least a 20 percent improvement in an individual's signs and symptoms of arthritis.

22 Mar 2004