Interferon gamma News and Research

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Acne may be a natural, transient inflammatory state when facial skin is exposed to microbes

Adolescent acne does not always result in a pathological condition; rather, it may be a natural, transient inflammatory state occurring when the maturing facial skin is exposed to new microbes and enhanced production of an oily substance called sebum, according to a Forum article published on September 26 in the journal Trends in Immunology.

25 Sep 2019

Scientists reveal cancer cells' immune weak spot

Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife.

27 Aug 2019

Antibody may help the immune system fight sepsis-related fungal infections

An antibody that blocks the "programmed cell death" pathway may help the immune system fight off sepsis-related fungal infections, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

12 Aug 2019

Tuberculosis still looms large over a fourth of the world’s people

A new Danish study concludes that a quarter of the people on earth have the tuberculosis bacillus within their bodies. This disease preys on over 10 million people annually, and kills 2 million a year. It is Number 1 on the list of killer diseases, far above AIDS and other infections.

5 Aug 2019

Researchers identify genes linked to death from sepsis in mice

Sepsis is a life-threatening condition that occurs when the body's immune response to infection spirals out of control.

23 Jul 2019

Standard tests may not detect low-level case of TB in some people

An international collaboration of infectious disease experts has identified a large group of people who appear to have naturally mounted an immune response to TB, a bacterial infection that is the leading cause of infectious disease death worldwide.

1 Jul 2019

Researchers develop model of intestinal infection that could advance vaccine development

The intestinal parasite Cryptosporidium, which causes a diarrheal disease, is very good at infecting humans. It's the leading cause of waterborne disease from recreational waters in the United States.

21 Jun 2019

Complex molecular conversation is key to the establishment of 'hot tumor'

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

11 Jun 2019

Nanotechnology treatment reverses multiple sclerosis symptoms in mice

A nanotechnology treatment derived from bone marrow stem cells has reversed multiple sclerosis symptoms in mice and could eventually be used to help humans, according to a new study led by University of California, Irvine researchers.

6 Jun 2019

New forms of older anti-cancer agent appear to enhance immune response to fight melanoma

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University School of Medicine report two new forms of an older anti-cancer agent they developed appear to enhance the immune system's ability to fight melanoma in mice.

20 Feb 2019

Interaction between two immune cells may play key role in fight against dengue virus

Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection.

8 Feb 2019

New rapid blood tests could speed up TB diagnosis, save the NHS money

Rapid blood tests used by the NHS are unable to rule out tuberculosis (TB) and should be replaced with a new, more accurate test, a study has found.

17 Jan 2019

QIAGEN and DiaSorin launch automated, CE-marked workflow for high-throughput TB screening

QIAGEN N.V. and DiaSorin today announced the introduction of an automated, CE-marked workflow for QIAGEN’s QuantiFERON-TB Gold Plus Blood Collection Tubes (QFT-Plus BCT) and a novel DiaSorin LIAISON Test on widely used immunodiagnostic instruments from DiaSorin.

17 Sep 2018

Researchers focus on uncoupling obesity from diabetes

About 422 million people around the world, including more than 30 million Americans, have diabetes. Approximately ninety percent of them have type 2 diabetes. People with this condition cannot effectively use insulin, a hormone made by the pancreas that helps the body turn blood sugar into energy.

15 Aug 2018

Researchers discover how chronic infections can outsmart the immune system

Like many chronic infections, visceral leishmaniasis thwarts the immune system's defenses so it can settle comfortably into its host.

1 Aug 2018

Genetic factors may play a role in progression of liver injury in Caucasians with hepatitis B infection

A new study has shown that genetic variation may increase the risk of severe liver damage in Caucasians with chronic hepatitis B infection.

27 Jul 2018

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Scientists at Dana-Farber/Brigham and Women's Cancer Center have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

19 Jul 2018

Researchers describe key role of enzyme in regulating immune response against Chagas disease parasite

In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.

16 Jul 2018

Researchers discover immune cells that create and sustain chronic inflammatory bowel disease

In preclinical experiments, Laurie Harrington, Ph.D., and colleagues at the University of Alabama at Birmingham have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease.

27 Jun 2018

New cancer vaccine yields promising results in clinical study

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

11 Apr 2018