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Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

25 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

Study explores the effects of ovulation inducing method on embryo quality

Low birth rates have become a serious problem in many developed countries throughout the world, with Japan being a prime example. In Japan particularly, aging and stress have led to a massive rise in infertility, which now affects one in every 4.4 couples.

22 Apr 2024

Study reveals shared brain mechanism of cocaine and morphine addiction

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

18 Apr 2024

New research pinpoints key pathways in prostate cancer's vulnerability to ferroptosis

Review examines the role of ferroptosis, an iron-dependent form of cell death, in prostate cancer, exploring its underlying molecular mechanisms and potential for targeted therapeutic strategies.

17 Apr 2024

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes.

16 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Wound warriors: How microbes influence healing and infection risks

Study explores how wound microbiota affect skin repair and infection risk by altering host immune responses, underscoring the complexity of microbial interactions in wound healing.

7 Apr 2024

Protein intake during pregnancy affects offspring's facial features

The protein content of the diet during pregnancy can affect the face of the offspring. This is shown in animal studies, and the underlying mechanism was also found in human genetic studies.

5 Apr 2024

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis.

2 Apr 2024

Rare variants in the YKT6 gene cause new neurological disorder, study finds

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

1 Apr 2024

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

28 Mar 2024

Study reveals protective role of C3 protein in insulin-producing cells

Although there are many differences between type 1 diabetes and type 2 diabetes, there are also similarities, such as inflammation of the insulin-producing cells.

21 Mar 2024

Unique bacteria colonize the gut shortly after birth and make serotonin to educate gut immune cells

A recent study revealed that neonatal gut bacteria produce serotonin and down-regulate monoamine oxidase A (MOA) to limit serotonin breakdown, thereby promoting immune tolerance.

20 Mar 2024

Newly discovered adhesion GPCR mayo controls midgut development in Drosophila

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

15 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Microfluidic chips advance neurodegenerative disease research

Researchers review the role of microfluidic chip models in understanding neurodegenerative diseases, offering insights into the disease mechanisms and potential for drug development through innovative lab-on-a-chip technologies.

14 Mar 2024

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine.

8 Mar 2024

Adipose-derived stem cell exosomes play protective roles in mitigating myocardial injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the expression and therapeutic potential of circRNAs from adipose-derived stem cell (ADSC) exosomes (ADSC-Exos) for cardiomyocyte injury.

7 Mar 2024

WSU researchers find potential ‘trojan horse’ for treating difficult bacterial infections

Bacteria can be tricked into sending death signals to stop the growth of their slimy, protective homes that lead to deadly infections, a new study demonstrates.

5 Mar 2024