Kidney News and Research

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Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

Patients with uncontrolled renovascular hypertension saw a significant improvement in their blood pressure with renal artery stent deployment. The multicenter HERCULES trial, evaluating the safety and effectiveness of the RX Herculink Elite Stent, found that patients with higher blood pressure levels at baseline had the most dramatic reduction in blood pressure following intervention.

31 Aug 2012

UH pharmacologist examines age-related oxidative, inflammatory stress

Gaining new insight to managing sodium balance and blood pressure, investigators at the University of Houston (UH) College of Pharmacy believe their work may identify future therapeutic targets to control hypertension.

30 Aug 2012

Israel's Ministry of Health approves Medgenics’ INFRADURE Phase I/II clinical trials for hepatitis C

Medgenics, Inc., the developer of Biopump, a novel technology for the sustained production and delivery of therapeutic proteins in patients using their own tissue, today announced that Israel's Ministry of Health (MOH) has approved two Phase I/II clinical trials to assess the safety and efficacy of INFRADURE in patients with hepatitis C.

30 Aug 2012

Transcatheter renal denervation reduces blood pressure in real world patients

Renal denervation successfully treats patients with resistant hypertension in real world patient populations, according to a study presented at ESC Congress 2012. The findings were presented by Dr Darren Mylotte from France.

28 Aug 2012

Copeptin estimates prognosis in patients with heart failure

Copeptin predicts prognosis in patients with heart failure, according to research presented at the ESC Congress today, August 25, by Professor Stefan St-rk from Germany.

28 Aug 2012

FDA approves Gilead’s Stribild to treat HIV-1 infection

The U.S. Food and Drug Administration today approved Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate), a new once-a-day combination pill to treat HIV-1 infection in adults who have never been treated for HIV infection.

28 Aug 2012

Women with severe aortic stenosis less likely to die following TAVI

Women with severe aortic stenosis are 40% less likely to die after transcatheter aortic valve implantation (TAVI) than men, reveals the latest data from the largest study to date of gender differences in outcomes after TAVI.

27 Aug 2012

Diaverum plans to increase peritoneal dialysis use among patients with ESRD

Diaverum, one of the world's leading renal care providers, is planning to give more patients the possibility to be treated with peritoneal dialysis to increase their quality of life.

27 Aug 2012

Renal denervation safe and effective in patients with treatment resistant hypertension

Renal denervation leads to significant and sustained blood pressure reduction for up to 18 months in patients with treatment resistant hypertension, according to research presented at ESC Congress 2012.

27 Aug 2012

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Extra pounds-even within the overweight but not obese range-are linked to a higher risk of recurrence of the most common type of breast cancer despite optimal cancer treatment, according to a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

27 Aug 2012

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Seattle Genetics, Inc. today announced the initiation of a phase Ib clinical trial evaluating SGN-75 in combination with everolimus (Afinitor) for patients with advanced metastatic renal cell carcinoma (RCC).

24 Aug 2012

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Waiting to treat the commonest viral infections in transplant recipients until they reach a certain threshold is better than prophylactically treating all recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

24 Aug 2012

Researchers deciphered function of claudin-10 gene in the kidney

Sodium chloride, better known as salt, is vital for the organism, and the kidneys play a crucial role in the regulation of sodium balance. However, the underlying mechanisms of sodium balance are not yet completely understood.

24 Aug 2012

Bristol-Myers Squibb terminates BMS-986094 Phase II development for treatment of hepatitis C

Bristol-Myers Squibb Company announced today that the Company has discontinued development of BMS-986094 (formerly known as INX-189), a nucleotide polymerase (NS5B) inhibitor that was in Phase II development for the treatment of hepatitis C.

24 Aug 2012

Diabetes risk may be higher in childhood cancer survivors who received radiotherapy

Childhood cancer survivors who underwent radiotherapy treatment that exposed their pancreas to radiation may be at higher risk of developing diabetes in later life, according to an Article published Online First in The Lancet Oncology.

23 Aug 2012

Serum autoantibodies predict IgA nephropathy disease progression

Study findings reveal that increasing serum levels of immunoglobulin G and IgA autoantibodies act as markers for progression of IgA nephropathy.

22 Aug 2012

CKD may raise stroke, bleeding risk in AF patients

Danish study results show that the presence of chronic kidney disease appears to raise the risk for stroke, systemic thromboembolism, and bleeding among patients with atrial fibrillation.

22 Aug 2012

UC San Diego, iSAEC partner to study genetics of drug induced renal injury

The International Serious Adverse Events Consortium (iSAEC) announced today it will collaborate with the University of California, San Diego School of Medicine and UC San Diego Skaggs School of Pharmacy and Pharmaceutical Science to research the genetics of drug induced renal injury (DIRI).

22 Aug 2012

Chemists develop new lab test to examine how DNA damage disrupts protein synthesis

Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information by causing modifications in DNA.

22 Aug 2012

CKD may raise stroke, bleeding risk in AF patients

Danish study results show that the presence of chronic kidney disease appears to raise the risk for stroke, systemic thromboembolism, and bleeding among patients with atrial fibrillation.

21 Aug 2012

Kidney News and Research

Renal artery stent revascularization reduces blood pressure in patients with severe hypertension

UH pharmacologist examines age-related oxidative, inflammatory stress

Israel's Ministry of Health approves Medgenics’ INFRADURE Phase I/II clinical trials for hepatitis C

Transcatheter renal denervation reduces blood pressure in real world patients

Copeptin estimates prognosis in patients with heart failure

FDA approves Gilead’s Stribild to treat HIV-1 infection

Women with severe aortic stenosis less likely to die following TAVI

Diaverum plans to increase peritoneal dialysis use among patients with ESRD

Renal denervation safe and effective in patients with treatment resistant hypertension

Obesity at diagnosis of breast cancer associated with increased risk of recurrence

Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Researchers deciphered function of claudin-10 gene in the kidney

Bristol-Myers Squibb terminates BMS-986094 Phase II development for treatment of hepatitis C

Diabetes risk may be higher in childhood cancer survivors who received radiotherapy

Serum autoantibodies predict IgA nephropathy disease progression

CKD may raise stroke, bleeding risk in AF patients

UC San Diego, iSAEC partner to study genetics of drug induced renal injury

Chemists develop new lab test to examine how DNA damage disrupts protein synthesis

CKD may raise stroke, bleeding risk in AF patients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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