Kidney News and Research

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Researchers identify new mitochondrial protein complex linked with type 2 diabetes

Researchers at Metabolic Solutions Development Company, LLC (MSDC) have identified a mitochondrial protein complex through which anti-diabetic drugs exert their insulin sensitizing effects when used to treat patients diagnosed with type 2 diabetes.

11 Jun 2012

Pre-operative aspirin therapy may reduce risk of acute kidney failure after CABG surgery

Aspirin taken for five days before a heart operation can halve the numbers of patients developing post-operative acute kidney failure, according to research presented at the European Anaesthesiology Congress in Paris.

11 Jun 2012

ADAM28 inhibits VWF-mediated cancer cell apoptosis and enhances lung metastases

ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute.

11 Jun 2012

Effective ways of detecting onset of kidney disease

Research led by an Arizona State University biomedical engineer and physicist to find more effective ways of detecting the onset of kidney disease is getting support from the National Institutes of Health.

8 Jun 2012

Nonin Medical releases EQUANOX Advance Model 8004CB Series neonatal/pediatric sensor

Nonin Medical, Inc. announced today the U.S. market release of its EQUANOX Advance Model 8004CB Series neonatal/pediatric sensor.

8 Jun 2012

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

Amgen today announced top-line results of the Phase 3 EVOLVE (EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events) trial, which evaluated Sensipar/Mimpara (cinacalcet) for the reduction of the risk of mortality and cardiovascular (CV) events among 3,883 patients with secondary hyperparathyroidism (HPT) and chronic kidney disease (CKD) receiving dialysis.

8 Jun 2012

U of M, AbSorber to evaluate XM-ONE in their Living Donor program

The transplantation unit at Jackson Memorial Hospital and the University of Miami, FL, USA has entered into a research project with the Allenex group company AbSorber. The project is a pilot study evaluating the endothelial cell cross match XM-ONE in their Living Donor program.

8 Jun 2012

Successful pregnancies common for female liver transplant recipients

New research confirms that successful pregnancies are common for female liver transplant recipients. The study appearing in the June issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, found miscarriage risk was lower and the live birth rate higher among women following liver transplantation than in the general U.S. population.

7 Jun 2012

Initial HSCT results from phase III trial on systemic sclerosis

Initial results from an international, investigator-initiated, open label phase III trial were presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism. Data indicate that haematopoietic stem cell transplantation (HSCT) results in better long term survival than conventional treatment for patients with poor prognosis early diffuse cutaneous systemic sclerosis.

7 Jun 2012

Studies evaluate transplantation potential and success of islet cells derived from pancreatic tissues

Two studies appearing in the current issue of Cell Transplantation, evaluate the transplantation potential and success of islet cells derived from pancreatic tissues, in addition to a clinical study that reports the occurrence of adverse events.

7 Jun 2012

Savient announces results from KRYSTEXXA Phase III trials on gout-related kidney disease

Savient Pharmaceuticals, Inc. announced that new data presented in an oral session at the European League Against Rheumatism (EULAR) 2012 congress showed that patients with refractory chronic gout (RCG) who also suffer from chronic kidney disease (CKD) responded to treatment with KRYSTEXXA (pegloticase) regardless of baseline CKD stage.

7 Jun 2012

Iron and micronutrient-enriched foodstuffs can fight against anaemia

Iron deficiency and the anaemia it can cause are a major public health problem, affecting 2 billion people worldwide: mostly young children and pregnant women in developing countries. Despite decades of research into prevention and treatment, the situation is not improving, and is even deteriorating in some countries. Africa and India have the highest levels of anaemia, with more than 50% of women affected. In India, the illness is thought to cause up to 40% of maternal deaths.

6 Jun 2012

Patients with type 2 diabetes have 20% increased risk of blood cancers

Patients with type 2 diabetes have a 20 percent increased risk of developing blood cancers, such as non-Hodgkin lymphoma, leukemia and myeloma, according to a new meta-analysis led by researchers at The Miriam Hospital.

6 Jun 2012

Firefly surgical technology sheds new light on kidney cancers

A surgical technology called Firefly is shedding new light on kidney cancers and helping doctors at MedStar Georgetown University Hospital remove tumors more safely and more efficiently while sparing the rest of the healthy kidney.

6 Jun 2012

New PD-1 blocking antibody shows promise against advanced kidney cancer

An antibody that helps a person's own immune system battle cancer cells shows increasing promise in reducing tumors in patients with advanced kidney cancer, according to researchers at Beth Israel Deaconess Medical Center.

5 Jun 2012

High levels of antibody molecule linked to increased rates of death from all diseases

Mayo Clinic researchers have identified an immune system deficiency whose presence shows someone is up to four times likelier to die than a person without it. The glitch involves an antibody molecule called a free light chain; people whose immune systems produce too much of the molecule are far more likely to die of a life-threatening illness such as cancer, diabetes and cardiac and respiratory disease than those whose bodies make normal levels. The study is published in the June issue of Mayo Clinic Proceedings.

4 Jun 2012

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Two clinical trials led by Johns Hopkins Kimmel Cancer Center researchers in collaboration with other medical centers, testing experimental drugs aimed at restoring the immune system's ability to spot and attack cancer, have shown promising early results in patients with advanced non-small cell lung cancer, melanoma, and kidney cancer.

2 Jun 2012

Lapatinib-pazopanib combination therapy not beneficial for patients with inflammatory breast cancer

Inflammatory breast cancer is a very aggressive type of cancer associated with early metastasis and poor survival rates, and the prognosis is even worse for patients with tumors expressing the ErbB2 receptor. The ErbB2-inhibiting drug lapatinib can slow the spread of cancer cells in individuals with advanced breast cancer who have already tried other chemotherapy medications.

2 Jun 2012

Reumofan Plus may have harmful pharmaceutical ingredients, warns FDA

The U.S. Food and Drug Administration is warning consumers that Reumofan Plus, marketed as a "natural" dietary supplement for pain relief and other serious conditions, contains several active pharmaceutical ingredients not listed on the label that could be harmful.

2 Jun 2012

First intercontinental Kidney Paired Donation

Medical history was made last December when a 31-year old Oklahoma woman donated her kidney to a stranger - a man living in Athens, Greece. In return, the Greek man's wife has donated one of her kidneys to someone in Wilkes-Barre, Pa., completing the first intercontinental kidney exchange and opening a door that potentially can save thousands of lives in the U.S. and worldwide. A donor from Trinidad and Tobago will soon travel to Denver to continue the chain.

2 Jun 2012

Kidney News and Research

Researchers identify new mitochondrial protein complex linked with type 2 diabetes

Pre-operative aspirin therapy may reduce risk of acute kidney failure after CABG surgery

ADAM28 inhibits VWF-mediated cancer cell apoptosis and enhances lung metastases

Effective ways of detecting onset of kidney disease

Nonin Medical releases EQUANOX Advance Model 8004CB Series neonatal/pediatric sensor

Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD

U of M, AbSorber to evaluate XM-ONE in their Living Donor program

Successful pregnancies common for female liver transplant recipients

Initial HSCT results from phase III trial on systemic sclerosis

Studies evaluate transplantation potential and success of islet cells derived from pancreatic tissues

Savient announces results from KRYSTEXXA Phase III trials on gout-related kidney disease

Iron and micronutrient-enriched foodstuffs can fight against anaemia

Patients with type 2 diabetes have 20% increased risk of blood cancers

Firefly surgical technology sheds new light on kidney cancers

New PD-1 blocking antibody shows promise against advanced kidney cancer

High levels of antibody molecule linked to increased rates of death from all diseases

Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer

Lapatinib-pazopanib combination therapy not beneficial for patients with inflammatory breast cancer

Reumofan Plus may have harmful pharmaceutical ingredients, warns FDA

First intercontinental Kidney Paired Donation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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