Kidney News and Research

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HealthGrades evaluates nation's top-performing hospitals in organ transplantation

HealthGrades, the nation's leading independent ratings organization, today made available to organ transplant patients a list of those hospitals with the best track record for survival and chances of receiving a donor organ. HealthGrades annual evaluation of the nation's top-performing hospitals in organ transplantation includes clinical quality data, based on patient outcomes, for each of the 210 adult acute care hospitals that perform transplants.

17 Nov 2010

LRI pleased with FDA Advisory Committee's approval of Benlysta for lupus

The Lupus Research Institute (LRI) and its National Coalition of state and local lupus organizations are pleased with the U.S. Food and Drug Administration (FDA) Advisory Committee's vote to recommend approval of Benlysta® for active systemic lupus erythematosus (SLE), offering patients new found hope for the first approved treatment option in more than 50 years.

17 Nov 2010

New layer of kidney cells can purify blood

Researchers at Eindhoven University of Technology (TU/e) and the University Medical Center Groningen have succeeded in culturing a layer of kidney cells in the lab. These cells maintained their functional properties, and are able to purify blood.

17 Nov 2010

Chimerix’s lipid-conjugated drugs reduces nephrotoxicity: Study

Scientists from Chimerix, Inc. today presented in vitro data demonstrating that the company's lipid-conjugated drugs, CMX001 and CMX157, are not substrates for the human Organic Anion Transporters (hOATs) and thus have significantly reduced potential to cause nephrotoxicity via this mechanism.

17 Nov 2010

AVEO commences enrollment in Phase 1b combination trial of tivozanib with oral capecitabine in advanced tumors

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today announced that it has initiated patient enrollment in an open-label, multi-center Phase 1b clinical trial evaluating tivozanib in combination with oral capecitabine (Xeloda®) in patients with certain advanced solid tumors.

17 Nov 2010

Reducing salt intake can enhance health of young adults in future: Research

Cutting back on salt in teenagers' diets by as little as one-half teaspoon, or three grams, a day, could reduce the number of young adults with high blood pressure by 44 to 63 percent, according to new research presented Sunday, Nov. 14 at the American Heart Association's Scientific Sessions 2010 meeting in Chicago.

16 Nov 2010

RBC boosting drugs may undermine breast cancer treatment with Herceptin

Red-blood-cell-boosting drugs used to treat anemia may undermine breast cancer treatment with Herceptin, a targeted therapy that blocks the cancer-promoting HER2 protein, researchers from The University of Texas MD Anderson Cancer Center report in the Nov. 16 edition of Cancer Cell.

16 Nov 2010

National health disparities conference wraps up with creative approaches, expectations for new healthcare reform

Focusing on the disparities in the quality of health care across demographic groups, the Fourth Annual National Conference on Health Disparities brought together White House officials and national and local healthcare executives to address a series of key questions about non-medical determinants of health quality and to recommend strategies to bring more equitable healthcare access to the underserved. The determinants discussed at the four-day-long conference, which began November 10, 2010 and concluded Saturday, November 13, 2010, included education levels, health literacy, poverty, public safety, community design, access to care, environmental quality and personal, government and corporate responsibility.

15 Nov 2010

Dialysis patients at elevated risk for sudden cardiac death: Study

Approximately 500,000 Americans require dialysis to treat kidney disease; of that population nearly half of the deaths that occur are caused by cardiovascular disease. Dialysis patients are at elevated risk for sudden cardiac death, but physicians are unclear why these deaths occur because little research has been done to examine how to best manage heart disease in this high-risk population.

15 Nov 2010

Research on E.Coli bacteria could help develop new vaccine for urinary tract infection

Urinary tract infections are a painful, recurring problem for millions of women. They are also getting more dangerous as bacteria develop resistance to the most common treatments.

15 Nov 2010

Nile third quarter net loss decreases to $1.8 million

Nile Therapeutics, Inc., a company focused on the development of novel therapeutics for therapeutics for cardiovascular disease, today announced its third quarter financial results for 2010.

12 Nov 2010

Abaxis releases new Piccolo reagent disc panel

Abaxis, Inc., a medical products company manufacturing point-of-care blood analysis systems, today announced the release of a new Piccolo® reagent disc panel called BioChemistry Panel Plus. This new reagent disc will be used by healthcare professionals in conjunction with the Piccolo Xpress™ point-of-care analyzer.

12 Nov 2010

Consent registry facilitates organ and tissue donation

Québec-Transplant and Héma-Québec applaud the government's commitment to assign the management of a consent registry for organ and tissue collection to the Régie de l'assurance-maladie du Québec (RAMQ), as stipulated in Bill 125, An Act to facilitate organ and tissue donation.

12 Nov 2010

ASN Annual Meeting to highlight six late-breaking clinical trials on nephrology

Six late-breaking clinical trials have been accepted for presentation next week during the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition in Denver, CO. These trials were selected based upon their potential impact to the field of nephrology.

12 Nov 2010

Elevated levels of MCP-1 found in urine of patients with acute kidney injury

The presence of certain markers in the urine might be a red flag for acute kidney injury (AKI), according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that a simple urine test could help prevent cases of kidney failure.

12 Nov 2010

Reata to present bardoxolone methyl Phase 2b clinical trial data for CKD, type 2 diabetes at ASN Conference

Reata Pharmaceuticals today announced that the company will present data on the primary endpoint from a pivotal Phase 2b clinical trial of bardoxolone methyl in patients with chronic kidney disease (CKD) and type 2 diabetes. The data will be presented in a late-breaking oral presentation at the American Society of Nephrology (ASN) Renal Week Conference to be held November 16-21, 2010, in Denver, Colorado.

12 Nov 2010

Diabetic drug may retard growth of fluid-filled cysts in PKD: Research

Researchers report that a drug commonly used to treat diabetes may also retard the growth of fluid-filled cysts of the most common genetic disorder, polycystic kidney disease.

12 Nov 2010

Bristol-Myers Squibb announces first large-scale diabetes initiative to develop self-management program

The Bristol-Myers Squibb Foundation today announced Together on Diabetes: Communities Uniting to Meet America's Diabetes Challenge, a 5-year, $100 million initiative to help patients living with type 2 diabetes better manage their disease beyond the doors of their doctor's office in their homes and communities and for the course of their disease.

12 Nov 2010

NephRx initiates NX001 Phase I clinical trial to prevent DGF in kidney transplant patients

NephRx Corporation today announced that it has initiated a Phase I clinical trial of its lead compound NX001 and has successfully dosed the first subject in the study. NX001, a kidney growth factor peptide that has demonstrated good safety and promising efficacy in two animal models of acute renal failure, is in development for the prevention of delayed graft function (DGF) in kidney transplantation patients.

11 Nov 2010

Colorado officials discover positive test for E. coli 0157:H7 in Mauri Gorgonzola cheese

Mauri Gorgonzola cheese with sell-by dates of 01/31/11 and 01/14/11 is being recalled because of a positive test for E. coli 0157:H7. DPI Specialty Foods of Tualatin, Ore., cut, packaged and distributed the cheese to Costco Wholesale Corporation (Costco) stores in Colorado.

11 Nov 2010

Kidney News and Research

HealthGrades evaluates nation's top-performing hospitals in organ transplantation

LRI pleased with FDA Advisory Committee's approval of Benlysta for lupus

New layer of kidney cells can purify blood

Chimerix’s lipid-conjugated drugs reduces nephrotoxicity: Study

AVEO commences enrollment in Phase 1b combination trial of tivozanib with oral capecitabine in advanced tumors

Reducing salt intake can enhance health of young adults in future: Research

RBC boosting drugs may undermine breast cancer treatment with Herceptin

National health disparities conference wraps up with creative approaches, expectations for new healthcare reform

Dialysis patients at elevated risk for sudden cardiac death: Study

Research on E.Coli bacteria could help develop new vaccine for urinary tract infection

Nile third quarter net loss decreases to $1.8 million

Abaxis releases new Piccolo reagent disc panel

Consent registry facilitates organ and tissue donation

ASN Annual Meeting to highlight six late-breaking clinical trials on nephrology

Elevated levels of MCP-1 found in urine of patients with acute kidney injury

Reata to present bardoxolone methyl Phase 2b clinical trial data for CKD, type 2 diabetes at ASN Conference

Diabetic drug may retard growth of fluid-filled cysts in PKD: Research

Bristol-Myers Squibb announces first large-scale diabetes initiative to develop self-management program

NephRx initiates NX001 Phase I clinical trial to prevent DGF in kidney transplant patients

Colorado officials discover positive test for E. coli 0157:H7 in Mauri Gorgonzola cheese

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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