Kidney News and Research

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Repeated stress signals made in cells with metabolism-associated disease encourage the growth of invading bacteria

Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tract.

28 Jul 2009

Intensive glucose control halves complications of longstanding type 1 diabetes

Near-normal control of glucose beginning as soon as possible after diagnosis would greatly improve the long-term prognosis of type 1 diabetes, concludes a study published in the July 27, 2009, issue of the Archives of Internal Medicine, which updates information about the clinical course of type 1 diabetes.

27 Jul 2009

'Urine NGAL' gives clues to kidney injury in ICU patients and HIV-related kidney disease

Acute kidney injury (AKI) is a frequent complication in patients in intensive care. A new laboratory test called urine neutrophil gelatinase associated lipocalin (NGAL) helps predict if patients will develop acute kidney injury, reports an upcoming study in the Journal of the American Society of Nephrology (JASN).

26 Jul 2009

Fresh meats often contain additives harmful to kidney disease patients

Uncooked meat products enhanced with food additives may contain high levels of phosphorous and potassium that are not discernable from inspection of food labels, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). This can make it difficult for people to limit dietary phosphorous and potassium that at high levels are harmful to kidney disease patients.

26 Jul 2009

Prehypertension, obesity and kidney disease risks

People with prehypertension are not at increased risk of kidney disease if their body mass index (BMI) is under 30.0 kg/m2, a first-ever examination of the combined effect of blood pressure and body weight on the risk of kidney disease shows.

21 Jul 2009

Potassium citrate wards off kidney stones in epilepsy patients on ketogenic diet

Children on the high-fat ketogenic diet to control epileptic seizures can prevent the excruciatingly painful kidney stones that the diet can sometimes cause if they take a daily supplement of potassium citrate the day they start the diet, according to research from Johns Hopkins Children's Center.

21 Jul 2009

Discovery of five genetic variants related to blood pressure in African-Americans

A team led by researchers from the National Institutes of Health (NIH) has reported the discovery of five genetic variants related to blood pressure in African-Americans, findings that may provide new clues to treating and preventing hypertension. The effort marks the first time that a relatively new research approach, called a genome-wide association study, has focused on blood pressure and hypertension in an African-American population.

17 Jul 2009

Sunitinib shows promise for advanced kidney cancer patients with poor prognosis

Sunitinib prolongs progression-free and overall survival, and is safe and well tolerated in advanced kidney cancer (metastatic renal cell carcinoma) patients with a poor prognosis such as the elderly and those whose cancer has spread to the brain, finds an Article published Online First (www.thelancet.com) and in the August edition of The Lancet Oncology.

16 Jul 2009

Dialysis treatments OK for patients who have had a heart attack

Dialysis treatments do not affect the heart health of kidney disease patients who have had a heart attack, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Since cardiovascular disease is the most common cause of death in kidney disease patients, the findings are good news for individuals who need the treatments.

9 Jul 2009

NDA for Exenatide once weekly accepted for FDA review

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the New Drug Application (NDA) for exenatide once weekly has been accepted for review by the U.S. Food and Drug Administration (FDA).

7 Jul 2009

Treatment blood pressure targets for hypertension

Aiming for lower than standard blood pressure targets offers no known clinical benefit, according to a Cochrane Review. In a systematic review of the evidence, researchers found that using antihypertensive drugs to reduce blood pressure below the 140/90 mm Hg standard was not associated with any reduction in death rates or serious morbidity.

7 Jul 2009

Combining two common medical tests provides new way to screen for serious kidney disease

The combination of two common medical tests can improve a doctor's ability to predict which patients will develop serious kidney disease, a research team led by the Norwegian University of Science and Technology (NTNU) reports in a recent issue of the Journal of the American Society of Nephrology.

7 Jul 2009

Johns Hopkins leads first 16-patient, multicenter "domino donor" kidney transplant

Surgical teams at The Johns Hopkins Hospital, Barnes-Jewish Hospital in St. Louis, INTEGRIS Baptist Medical Center in Oklahoma City and Henry Ford Hospital in Detroit successfully completed the first eight-way, multihospital, domino kidney transplant. The transplant involved eight donors - 3 men and 5 women along with eight organ recipients - 3 men and 5 women. "All Johns Hopkins patients are in good condition and are recovering as anticipated," according to Robert A. Montgomery, M.D., Ph.D., director of the Johns Hopkins Comprehensive Transplant Center.

7 Jul 2009

For America's aged, surgery at any price?

When doctors decide whether or not to go ahead with an expensive surgery, "age is no longer the deciding factor, even for invasive treatment such as open-heart surgery," The Philadelphia Inquirer reports.

7 Jul 2009

Future of organ transplantation - microscopic beads that create "designer " immune cells

The future of organ transplantation could include microscopic beads that create "designer" immune cells to help patients tolerate their new organ, Medical College of Georgia researchers say.

6 Jul 2009

Discovery of a genetic link to risk of kidney stones and osteoporosis

A discovery by scientists at deCODE genetics and academic colleagues from Iceland, the Netherlands and Denmark has pointed to a common biological mechanism contributing to both kidney stones and decreased bone mineral density (BMD).

30 Jun 2009

Enzyme fights mutated protein in inherited Parkinson's disease

An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson's disease, researchers at UT Southwestern Medical Center have found.

28 Jun 2009

Blood pressure cuff could help improve the success of kidney transplants

The first clinical trial funded by the new Efficacy and Mechanism Evaluation (EME) programme will investigate whether a simple procedure to activate one of the body's natural defence mechanisms improves the function of kidneys after transplantation. This research is funded by the Medical Research Council and managed by the National Institute for Health Research.

25 Jun 2009

Telehealth Solutions launches CardioPod for NHS Health Check

Telehealth Solutions has today launched the CardioPod, a system to facilitate the new NHS Health Check nationwide. The CardioPod will be installed in pharmacies and GP surgeries across England, allowing patients easy access to an NHS Health Check carried out by a trained professional, who will give expert advice on their cardiovascular risk score and what action they can take to reduce the risk of heart disease, stroke, type II diabetes and kidney disease.

24 Jun 2009

Underweight and extremely obese die earlier

Underweight people and those who are extremely obese die earlier than people of normal weight - but those who are overweight actually live longer than people of normal weight.

24 Jun 2009