Laboratory News and Research

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New tool helps identify nonadherent HIV patients

Researchers have developed a simple tool that predicts virologic response and development of drug resistance in patients receiving HIV treatment, based on how regularly they attend their scheduled health appointments.

26 Nov 2012

Cancer-killing viruses found safe but less effective than expected

Doctors now use cancer-killing viruses to treat some patients with lethal, fast-growing brain tumors. Clinical trials show that these therapeutic viruses are safe but less effective than expected.

26 Nov 2012

Weight loss and quality of sleep: an interview with Kerry Stewart

In our particular study we used a survey which consisted of 50 different questions which get at different aspects of sleep health. It was a patient self-report.

26 Nov 2012

Ivoclar Vivadent announces acquisition of Wieland Dental

Ivoclar Vivadent, headquartered in Schaan, Liechtenstein, announced the acquisition of Wieland Dental today. The acquisition is planned to be completed in the fourth quarter of 2012. The transaction is still subject to approval by the German Federal Cartel Office.

26 Nov 2012

Allergy Centre of the Charité-Universitätsmedizin Berlin to host three international scientific conferences

The Allergy Centre of the Charité-Universitätsmedizin Berlin will host three international scientific conferences in the upcoming week. According to Prof. Marcus Maurer, Associate Director of the Allergy Centre at the Clinic for Dermatology, Venereology and Allergology: "Allergological issues have been gaining in importance among clinical physicians." Prof. Mauer explains that all three conferences are focused on enabling scientific exchange about basic allergy research: "Our intent is to offer clinical physicians the opportunity to learn something about the cells, the basis for allergological illnesses.

23 Nov 2012

Researchers trace specific paths of chandelier cells during development into the cerebral cortex

The cerebral cortex of the human brain has been called "the crowning achievement of evolution." Ironically, it is so complex that even our greatest minds and most sophisticated science are only now beginning to understand how it organizes itself in early development, and how its many cell types function together as circuits.

23 Nov 2012

Major advance in understanding how flu viruses replicate within infected cells

Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to "see" one of influenza's essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus's vulnerabilities that are sure to be of interest to drug developers.

23 Nov 2012

Researchers characterize novel lysosomal PQ protein linked to cystinosis

Researchers at the Université Paris Descartes/CNRS and the Université libre de Bruxelles have made a major breakthrough in the study of cystinosis, a genetic disease that can lead to serious disorders, notably fatal kidney failure.

23 Nov 2012

Researchers create 3D map of rod sensory cilium architecture affected by mutation

Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine (www.bcm.edu) have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.

23 Nov 2012

Breakthrough in heart research

Breakthrough in heart research: The research team from Professor Katja Schenke-Layland of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs).

22 Nov 2012

Computational apolipoprotein estimates ‘reliable’ for cardiovascular risk

Computational estimates of apolipoprotein B and apolipoprotein A1 can be used as reliable markers for atherosclerosis, report researchers.

22 Nov 2012

Many microorganisms have ability to combat nitrous oxide

The environment has a more formidable opponent than carbon dioxide. Another greenhouse gas, nitrous oxide, is 300 times more potent and also destroys the ozone layer each time it is released into the atmosphere through agricultural practices, sewage treatment and fossil fuel combustion.

22 Nov 2012

New approach could help orthopaedic surgeons better deal with battlefield injuries

Bones are resilient and heal well after most fractures. But in cases of traumatic injury, in which big pieces of bone are missing, healing is much more difficult, if not impossible. These so-called "large segmental defects" are a major clinical problem, and orthopaedic surgeons struggle to treat them, especially among the military in places like Afghanistan.

22 Nov 2012

Important knowledge about how stem cells develop best into insulin-producing cells

Scientists from The Danish Stem Cell Center (DanStem) at the University of Copenhagen are contributing important knowledge about how stem cells develop best into insulin-producing cells. In the long term this new knowledge can improve diabetes treatment with cell therapy.

22 Nov 2012

IRCM researchers discover a nerve cell's internal clock

A team of IRCM researchers, led by Dr. Fr-d-ric Charron, recently uncovered a nerve cell's internal clock, used during embryonic development.

22 Nov 2012

Kidney tumors may be smarter than previously thought

New research has found there are several different ways that kidney tumours can achieve the same result - namely, grow.

22 Nov 2012

Somnogen induces sleep in patients with primary hypersomnia

Researchers at Emory University School of Medicine have discovered that dozens of adults with an elevated need for sleep have a substance in their cerebrospinal fluid that acts like a sleeping pill.

22 Nov 2012

Computational apolipoprotein estimates ‘reliable’ for CV risk

Computational estimates of apolipoprotein B and apolipoprotein A1 can be used as reliable markers for atherosclerosis, report researchers.

21 Nov 2012

Electrophysiology: an interview with Dr Kaylene Young

Bioelectricity is an essential part of our make-up. All cells in our body communicate by electrical activity. If an electrical charge is applied to one of our muscles it will interpret that electrical activity as a signal telling it to contract.

21 Nov 2012

Discovery of DKK1-WNT pathway reveals new drug targets for Alzheimer's

The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer's patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease. The study gives the most detailed understanding yet of the complex processes leading to Alzheimer's.

21 Nov 2012