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Stem cells to repair heart tissue soon after a heart attack

Stem cells derived from human heart tissue develop into multicellular, spherical structures called cardiospheres that express the normal properties of primitive heart tissue, smooth muscle and blood vessel cells, according to a study by Johns Hopkins researchers.

20 Nov 2005

Two tests in a lifetime will halve cervical cancer numbers in poor countries

Most women in developed countries are regularly screened for cervical cancer, but this is often not the case in poorer countries.

20 Nov 2005

Scientists use stem cells to grow cartilage

Scientists from Imperial College London have successfully converted human embryonic stem cells into cartilage cells, offering encouragement that replacement cartilage could one day be grown for transplantation.

16 Nov 2005

World first trial grows blood vessels from patient's own skin

A team of American scientists have successfully implanted blood vessels grown entirely from a patient's own cells.

16 Nov 2005

Link between eating and pain relief - brain stem blocks pain to protect key behaviors

Certain behaviors, such as eating, drinking and urinating, are so crucial to survival that the brains of all vertebrates contain clusters of nerve cells that can suppress pain long enough to allow the animal to eat, drink - or pee - in peace.

15 Nov 2005

Better understanding of cancer cachexia

New research shows that a wasting condition responsible for nearly a third of all cancer deaths involves the loss of an essential muscle protein that is also lost in people with muscular dystrophy.

15 Nov 2005

Early changes in the oxygenation of the skin may help predict foot disease in diabetes patients

Foot ulcerations are one of the most serious complications of diabetes, resulting in more than 80,000 lower-leg amputations each year in the U.S. alone.

14 Nov 2005

Speed of PSA increase matters more than PSA level

In the largest study of its kind to date, Mayo Clinic researchers report that prostate specific antigen (PSA) kinetics, both velocity and doubling time, can be used to predict disease progression and likelihood of death after radical prostatectomy surgery, suggesting that this could be used to guide treatment decisions.

14 Nov 2005

Biomedical device allows stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far more research

Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems.

14 Nov 2005

Discovery of novel form of regulation of the GLI1 gene

The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.

14 Nov 2005

Researchers can now identify patients likely to respond to cancer drug therapy

Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.

13 Nov 2005

Link between diet and epileptic seizures studied

Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works.

13 Nov 2005

Cellular signal may determine life or death for damaged brain cells

Scientists at the Universities of Heidelberg and Ulm and a unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have discovered that a specific signal within brain cells may determine whether they live or die after a stroke.

13 Nov 2005

Promising functional readouts of immunity in a blood-stage malaria vaccine trial

A malaria vaccine remains the most desired tool to combat the worsening malaria epidemic in many developing countries. Pierre Druilhe and colleagues (from the Institut Pasteur in Paris) have completed the first human trial of a vaccine based on MSP3, a protein present on the surface of the malaria parasite, with very encouraging results.

13 Nov 2005

Zyflamend shows promise in the early treatment of prostate cancer

Data from the Columbia University Department of Urology demonstrates that Zyflamend, a unique herbal extract preparation, suppresses the growth of prostate cancer cells and induces prostate cancer cells to self-destruct via a process called "apoptosis."

13 Nov 2005

Early to bed helps learning ability at school

When children stay up late, they have more academic and attention problems at school, according to a new study from Brown Medical School to be published in the December issue of the journal SLEEP.

13 Nov 2005

Vaccine for a type of blood cancer - follicular lymphoma

A team of researchers has demonstrated the clinical efficacy and benefits of a vaccine for a type of blood cancer, follicular lymphoma, amongst first time relapse patients. Specialists from two University of Navarre centres – the University Hospital and the Research Centre for Applied Medicine (CIMA) - have worked jointly since 2001 on the research.

9 Nov 2005

Introgen's INGN 241 combined with Celebrex kills breast cancer cells

Introgen Therapeutics, Inc. today reported the publication of preclinical data demonstrating that INGN 241 works synergistically with celecoxib (Celebrex) marketed by Pfizer to inhibit the growth and increase apoptosis (cell death) of breast cancer cells.

8 Nov 2005

LGC licenses first DNA test for response to schizophrenia treatment from the Institute of Psychiatry, King’s College London

LGC, Europe's leading independent analytical laboratory providing advanced chemical, biochemical and forensic analysis, has announced an exclusive agreement with King’s College London to offer the first pharmacogenetic screening service which will predict whether a patient with schizophrenia will respond positively to the antipsychotic drug clozapine.

8 Nov 2005

Dead poultry in Saudi tested for bird flu

According to local media reports, veterinary authorities are carrying out tests in order to determine whether poultry found dead in a farm in southwestern Saudi Arabia were infected with the bird flu virus.

8 Nov 2005