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Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

The gut is a well-established route of infection and target for viral damage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19. This is supported by the clinical observation that about half of COVID-19 patients exhibit gastrointestinal (GI) symptoms.

8 Apr 2021

Probiotic supplements increase the diversity of intestinal bacteria in extremely preterm infants

Extremely preterm infants can suffer from a life-threatening inflammation of the gut. A new clinical study has shown that supplements of a lactic acid bacterium may have positive effects by increasing the diversity of intestinal bacteria in these infants.

11 Mar 2021

Research shows a causal relationship between neonatal antibody production and maternal microbiota

A healthy system of gut bacteria, or microbiota, is crucial to health: Gut bacteria not only aid with digestion, but also play an important role in the body's immune response. Infants, however, are not born with full-fledged gut microbiota, which makes it difficult for them to fight off intestinal infections.

3 Mar 2021

Probiotics may be beneficial in COVID-19 treatment

A new study explores the role of common probiotics in managing the disease, which could prove to be of great value, given the emergence of new variants and the broad spectrum of clinical disease in COVID-19.

17 Feb 2021

New gut microbiome-based approach may have translational potential for cancer immunotherapy

Scientists from Nanjing University and the University of Macau have devised a new approach to extend the survival of transplanted probiotics in vivo, enhancing the efficacy of cancer chemo-/immunotherapies in mice.

11 Feb 2021

Study shows how gut bacteria can dull the efficacy of radiotherapy

A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received by about half of all cancer patients.

26 Jan 2021

Probiotics as adjuvant therapy for COVID-19 patients

In a recent review published in the Journal of Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Luigi Santacroce and Francesco Inchingolo et al. address the many factors such as dysbiosis (imbalance in the microbiota) that could influence the SARS-CoV-2 infection course.

25 Jan 2021

Few organisms in the gut microbiome found to play a key role in type 2 diabetes

Researchers at Oregon State University have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease affecting roughly one in 10 Americans.

4 Jan 2021

Scientists provide insight on how lung bacteria protect against invading pathogens

New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal.

8 Dec 2020

The vaginal microbiome may impact the efficacy of HIV prevention therapy

A new study has revealed that vaginal microbial communities are linked with an increased risk of HIV acquisition and may also impact the efficacy of PrEP.

3 Dec 2020

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

28 Oct 2020

Intestinal microbiota offers new prospects for treating celiac disease

Celiac disease is an immune disease of the intestine that affects more than 1% of the population. It is characterised by gluten intolerance that causes inflammation of the gut, abdominal pain and diarrhoea, and can lead to weight loss and deficiencies among patients.

23 Oct 2020

Gut microbiota composition and function not related to onset of gestational diabetes

Maternal overweight and obesity increase the risk of gestational diabetes mellitus. Gut microbiota composition has recently been associated with both overweight and a range of metabolic diseases.

9 Sep 2020

Scientists investigate the role of contractility and microbiota in chronic constipation

Chronic constipation (CC) remains a serious medical and social problem because the complexity of diagnosis, the lack of a single approach to treatment, and unsatisfactory treatment results.

20 Aug 2020

Developing new fluorescent metal sensors to peer into the gastrointestinal tract

A University of Houston researcher is developing a new set of metal sensors that will be able to function in the gastrointestinal tract, a low oxygen environment, to examine how gut bacteria respond when trace metal nutrients, like iron and zinc, are thrown out of balance either through diet or disease.

19 Aug 2020

Gut microbiome may play a part in severe COVID-19

A recent study published on the preprint medRxiv* in August 2020 reports on the evidence that the gut microbiome may play a part in severe COVID-19 infection.

19 Aug 2020

Daily cranberry intake could reduce H. pylori infections

A new clinical trial found consuming cranberry juice containing 44 mg of proanthocyanidins (or "PACs") per 240-mL serving twice daily for eight weeks resulted in a 20% reduction in the H. pylori infection rate in Chinese adult participants, when compared to those consuming lower amounts of juice and a placebo.

18 Aug 2020

Essential microbe produces significant amounts of vitamin B12 in fermented grain materials

Vitamin B12 is an essential micronutrient that is needed for functions such as maintaining the nervous system and forming blood cells.

4 Aug 2020

Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

Mother's prenatal psychological distress is linked to infant gut microbes

Mother's chronic prenatal psychological distress and elevated hair cortisol concentrations are associated with gut microbiota composition of the infant, according to a new publication from the FinnBrain research project of the University of Turku, Finland.

23 Jun 2020