Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Scientists target hunger's complex chemistry to yield promising treatments for obesity

Discoveries of hormones related to weight and appetite in the '90s helped spur a search for obesity treatments targeting those hormones-- with disappointing results.

29 Mar 2017

Researchers identify appetite-suppression mechanism in flies

Researchers have identified a molecule sent by fat cells to the fly brain that senses when they have had enough food and inhibits feeding, according to a study publishing March 28 in the open access journal PLOS Biology by Walton Jones of the Korea Advanced Institute of Science and Technology in Daejeon, and colleagues.

29 Mar 2017

Whole-body vibration can mimic muscle, bone health benefits of regular exercise in mice

A less strenuous form of exercise known as whole-body vibration can mimic the muscle and bone health benefits of regular exercise in mice, according to a new study published in the Endocrine Society's journal Endocrinology.

16 Mar 2017

Hormone secreted by bone cells can suppress appetite, mice study reveals

A hormone secreted by bone cells can suppress appetite, according to mouse studies conducted by Columbia University Medical Center researchers.

8 Mar 2017

New study sheds light on how prenatal BPA exposure increases obesity risk

An expectant mother's exposure to the endocrine-disrupting chemical bisphenol A (BPA) can raise her offspring's risk of obesity by reducing sensitivity to a hormone responsible for controlling appetite, according to a mouse study published in the Endocrine Society's journal Endocrinology.

8 Feb 2017

Researchers identify ion channel required for proper regulation of basal metabolism and body weight

UT Southwestern Medical Center researchers have identified an ion channel required for brain cells to suppress eating behavior in response to the hormone leptin or to the anti-obesity drug lorcaserin.

7 Feb 2017

Increased levels of physical activity linked to decreased insulin resistance, inflammation biomarkers

A new report, based on data from the Framingham Heart Study (FHS), suggests that insulin resistance, a predictor of cardiovascular risk and the development of diabetes, may be modulated with even modest levels of physical activity.

27 Jan 2017

Physician explains how poor or low-quality sleep hinders common resolutions

Making New Year's resolutions is easy. Keeping them — beyond a couple of weeks, at least — is tough.

20 Jan 2017

CSHL scientists create first model of genetically induced obesity in fruit flies

Why do people become obese? Poor dietary choices and overeating seem like clear causes, but what is at the root of these behaviors? Significantly overweight people may be genetically predisposed to be affected disproportionately when faced with the ready availability of calorie-laden treats.

11 Jan 2017

Study shows effects of intensive weight reduction on normal weight females

Worries about the potential negative consequences of fat loss regimens for aesthetic purposes in normal weight females have been surfacing in the media.

11 Jan 2017

Western diet during pregnancy may increase obesity risk in offspring

Diet composition around the time of pregnancy may influence whether offspring become obese, according to a new study using animal models at The Scripps Research Institute (TSRI).

15 Dec 2016

Karolinska Institute biologist receives 2016 Naomi Berrie Award for excellence in diabetes research

Columbia University has awarded the 2016 Naomi Berrie Award for Outstanding Achievement in Diabetes Research to Peter Arner, MD, PhD, a Distinguished Professor in the Department of Medicine at the Karolinska Institute, whose studies on the turnover of fat tissue in the human body has revealed processes that contribute to obesity and diabetes.

23 Nov 2016

Vitamin B12 deficiency during pregnancy may predispose children to type-2 diabetes

B12 deficiency during pregnancy may predispose children to metabolic problems such as type-2 diabetes, according to research presented today at the Society for Endocrinology's annual Conference in Brighton.

7 Nov 2016

Sleep-deprived people may consume extra calories , study finds

Sleep deprivation may result in people consuming more calories during the following day, according to a systematic review and meta-analysis led by researchers at King's College London.

2 Nov 2016

Research findings raise hope for better treatment of diabetic wounds

Diabetics often have to contend with wounds that heal poorly. Researchers at the Max Planck Institute for Biology of Ageing, the CECAD Excellence Cluster and the Institute of Genetics of the University of Cologne have now gained fresh insights into the underlying cellular mechanisms.

12 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

Leptin News and Research

Further Reading

Scientists target hunger's complex chemistry to yield promising treatments for obesity

Researchers identify appetite-suppression mechanism in flies

Whole-body vibration can mimic muscle, bone health benefits of regular exercise in mice

Hormone secreted by bone cells can suppress appetite, mice study reveals

New study sheds light on how prenatal BPA exposure increases obesity risk

Researchers identify ion channel required for proper regulation of basal metabolism and body weight

Increased levels of physical activity linked to decreased insulin resistance, inflammation biomarkers

Physician explains how poor or low-quality sleep hinders common resolutions

CSHL scientists create first model of genetically induced obesity in fruit flies

Study shows effects of intensive weight reduction on normal weight females

Western diet during pregnancy may increase obesity risk in offspring

Karolinska Institute biologist receives 2016 Naomi Berrie Award for excellence in diabetes research

Vitamin B12 deficiency during pregnancy may predispose children to type-2 diabetes

Sleep-deprived people may consume extra calories , study finds

Research findings raise hope for better treatment of diabetic wounds

Study identifies mechanistic link between maternal obesity and childhood hypertension

Researchers discover how appetite is controlled and influenced by the brain

Researchers discover potential new therapeutic target for treating obesity

New study reveals endocrine biological function of brown adipose tissue

DGIST researchers uncover mechanisms that control appetite during low glucose conditions in the brain

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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