Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

New driver of atherosclerosis may prove to be promising therapeutic target

A new driver of atherosclerosis has been identified by researchers at UT Southwestern Medical Center. This molecule, known as 27HC (27-hydroxycholesterol), has been found to exacerbate the development of the condition, and may prove to be a promising therapeutic target.

20 Jun 2014

Healthy inflammation necessary to prevent metabolic diseases, study finds

Chronic tissue inflammation is typically associated with obesity and metabolic disease, but new research from UT-Southwestern Medical Center now finds that a level of "healthy" inflammation is necessary to prevent metabolic diseases, such as fatty liver.

19 Jun 2014

Lipids efficiently kill leukemia cells

T cells use a novel mechanism to fight leukemia. They may recognize unique lipids produced by cancer cells and kill tumor cells expressing these lipid molecules.

17 Jun 2014

Growth hormone levels may manifest in signs of aging

The decreased production of growth hormone is caused by a physiological process known as somatopause, which practically affects the entire body, since it's involved in body composition, metabolism, bone mineral density and cardiovascular function.

16 Jun 2014

Low cholesterol may increase mortality risk in patients with kidney cancer

People are often told to reduce their cholesterol to improve their heart health, but new research suggests that low cholesterol may increase kidney cancer patients' risk of dying from their disease. The findings, which are published in BJU International, indicate that cholesterol testing may help doctors as they monitor and treat patients with kidney cancer.

12 Jun 2014

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first-the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched.

11 Jun 2014

Cerenis’ SAMBA and MODE Phase II Studies Meet Primary Endpoints for Treatment of FPHA, HoFH

Cerenis Therapeutics, the biopharmaceutical company, today announced that two of its Phase II studies, SAMBA and MODE (Modifying Orphan Disease Evaluation), with CER-001, an engineered human apoA-I-containing pre-β HDL mimetic, met their primary clinical endpoints in patients with Familial Primary Hypoalphalipoproteinemia (FPHA) and Homozygous Familial Hypercholesterolemia (HoFH), respectively.

2 Jun 2014

New genes involved in taste perception effective in weight loss and improve quality of life

New understanding of the genes involved in taste perception and food preferences could lead to personalised nutrition plans effective not just in weight loss but in avoiding diseases such as cancer, depression, and hypertension, Italian researchers will tell the annual conference of the European Society of Human Genetics (ESHG) today (Monday).

2 Jun 2014

ASCO honors St. Jude researcher with 2014 Pediatric Oncology Award

The American Society of Clinical Oncology (ASCO) has named Leslie L. Robison, Ph.D., of St. Jude Children's Research Hospital the recipient of the 2014 Pediatric Oncology Award for his contributions to the field of childhood cancer survivorship research.

31 May 2014

Computer simulations offer potential treatment option for dry eye syndrome

A treatment for dry eye-a burning, gritty condition that can impair vision and damage the cornea-could some day result from computer simulations that map the way tears move across the surface of the eye.

29 May 2014

Cholesterol plays vital role in cell mobility and tissue invasion

University of Barcelona's researchers led by Professor Carles Enrich, from the Department of Cell Biology, Immunology and Neurosciences of the Faculty of Medicine at the University of Barcelona and CELLEX Biomedical Research Centre of IDIBAPS, have found that cholesterol plays a key role in cell mobility and tissue invasion.

21 May 2014

Combination of metformin and rapamycin shows potential in treating aging and related diseases

A proven approach to slow the aging process is dietary restriction, but new research in the Linus Pauling Institute at Oregon State University helps explain the action of a drug that appears to mimic that process - rapamycin.

21 May 2014

Research shows sugar has direct effect on cardiovascular risk-factors independent of weight gain

Researchers from New Zealand's University of Otago have uncovered evidence that sugar has a direct effect on risk factors for heart disease, and is likely to impact on blood pressure, independent of weight gain.

16 May 2014

New tech could take light-based cancer treatment deep inside the body

Photodynamic therapy (PDT) is an effective treatment for easily accessible tumors such as oral and skin cancer.

15 May 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Isis Pharmaceuticals, Inc. announced today positive data from a Phase 2 study of ISIS-GCGRRx in patients with type 2 diabetes uncontrolled on stable metformin therapy.

14 May 2014

Mylan releases generic version of Zyprexa Zydis Tablets

Mylan Inc. today announced that it has launched Olanzapine Orally Disintegrating Tablets (ODT), 5 mg, 10 mg, 15 mg and 20 mg, the generic version of Eli Lilly and Company's Zyprexa Zydis Tablets.

14 May 2014

Intensive insulin treatment improves survival for diabetic heart attack patients

Long-term follow-up of the DIGAMI 1 trial – a landmark study of type 2 diabetes in Sweden – shows that intensive insulin treatment prolonged life by more than 2 years in patients with diabetes after a heart attack, compared with standard treatment for diabetes, reports Dr Viveca Ritsinger from the Unit of Cardiology of the Department of Medicine, Karolinska Institute, Stockholm, Sweden and colleagues in The Lancet Diabetes & Endocrinology.

14 May 2014

Anti-cancer drug delivery method smuggles drug into cancer cell before triggering release

Biomedical engineering researchers have developed an anti-cancer drug delivery method that essentially smuggles the drug into a cancer cell before triggering its release.

12 May 2014

Low-carbohydrate diet reduces inflammation in patients with type 2 diabetes

A low-carbohydrate diet, but not a low-fat diet, reduces inflammation in patients with type 2 diabetes, according to research at Linköping University in Sweden.

8 May 2014

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Lipids, primarily cholesterol and triglycerides, come from two sources: what is naturally manufactured in the liver and what comes from the intestines through the diet.

From Sanofi 7 May 2014

Lipids News and Research

Further Reading

New driver of atherosclerosis may prove to be promising therapeutic target

Healthy inflammation necessary to prevent metabolic diseases, study finds

Lipids efficiently kill leukemia cells

Growth hormone levels may manifest in signs of aging

Low cholesterol may increase mortality risk in patients with kidney cancer

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Cerenis’ SAMBA and MODE Phase II Studies Meet Primary Endpoints for Treatment of FPHA, HoFH

New genes involved in taste perception effective in weight loss and improve quality of life

ASCO honors St. Jude researcher with 2014 Pediatric Oncology Award

Computer simulations offer potential treatment option for dry eye syndrome

Cholesterol plays vital role in cell mobility and tissue invasion

Combination of metformin and rapamycin shows potential in treating aging and related diseases

Research shows sugar has direct effect on cardiovascular risk-factors independent of weight gain

New tech could take light-based cancer treatment deep inside the body

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Mylan releases generic version of Zyprexa Zydis Tablets

Intensive insulin treatment improves survival for diabetic heart attack patients

Anti-cancer drug delivery method smuggles drug into cancer cell before triggering release

Low-carbohydrate diet reduces inflammation in patients with type 2 diabetes

Controlling low-density lipoprotein-cholesterol levels: an interview with Jay Edelberg, M.D., Sanofi and Bill Sasiela, Ph.D., Regeneron

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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